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http://hdl.handle.net/20.500.12188/14966| Наслов: | Quantitative mass spectrometry evaluation of human retinol binding protein 4 and related variants | Authors: | Kiernan, Urban A Phillips, David A Trenchevska, Olgica Nedelkov, Dobrin |
Issue Date: | 30-мар-2011 | Publisher: | Public Library of Science (PLoS) | Journal: | PloS one | Abstract: | Retinol Binding Protein 4 (RBP4) is an exciting new biomarker for the determination of insulin resistance and type 2 diabetes. It is known that circulating RBP4 resides in multiple variants which may provide enhanced clinical utility, but conventional immunoassay methods are blind to such differences. A Mass Spectrometric immunoassay (MSIA) technology that can quantitate total RBP4 as well as individual isoforms may provide an enhanced analysis for this biomarker. | URI: | http://hdl.handle.net/20.500.12188/14966 | DOI: | 10.1371/journal.pone.0017282 |
| Appears in Collections: | Faculty of Natural Sciences and Mathematics: Journal Articles |
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