Comparative Analysis of Bioinformatics Tools Used in HIV-1 Studies
Date Issued
2013
Author(s)
Kareski, Daniel
Abstract
The HIV-1 virus is one of most studied viruses because of the
incredible ability to morph its genetic structure. Sequencing
the virus and generating phylogenetic trees gives us the
ability to recognise the evolutionary changes of the virus and
possibly help in finding a cure. Bioinformatics offers great
choice of tools that are used in the process of generating
phylogenetic trees. Different factors contribute in the usage of
one tool over another and in order to compare phylogenetic
quality of a tree we use the bootstrapping method. In this
paper HIV-1 bioinformatics tools used in studies conducted in
the Balkan Peninsula are presented, and comparative analysis
of those tools is elaborated. The tools utilised in these studies
are used in processing random data. The results of their usage
is also presented.
incredible ability to morph its genetic structure. Sequencing
the virus and generating phylogenetic trees gives us the
ability to recognise the evolutionary changes of the virus and
possibly help in finding a cure. Bioinformatics offers great
choice of tools that are used in the process of generating
phylogenetic trees. Different factors contribute in the usage of
one tool over another and in order to compare phylogenetic
quality of a tree we use the bootstrapping method. In this
paper HIV-1 bioinformatics tools used in studies conducted in
the Balkan Peninsula are presented, and comparative analysis
of those tools is elaborated. The tools utilised in these studies
are used in processing random data. The results of their usage
is also presented.
Subjects
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