Naumovska, Zorica
Preferred name
Naumovska, Zorica
Official Name
Naumovska, Zorica
Main Affiliation
Email
zose@ff.ukim.edu.mk
21 results
Now showing 1 - 10 of 21
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Item type:Publication, Antibiotic dispensing and over the counter drug sale: case study in “Villa” community pharmacy in Montenegro 2019-2021(Macedonian pharmaceutical association, 2022) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Knowledge, opinions and attitudes of the general population in the Republic of N. Macedonia about vaccines and vaccination(Macedonian pharmaceutical association, 2022); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Pharmacists` vaccine basic knowledge and attitudes in the RN Macedonia(Macedonian pharmaceutical association, 2022); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Community pharmacy practice in Montenegro in the period January-April 2020(Macedonian pharmaceutical association, 2022); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Antibiotic Consumption in Hospitalized Children at the University Clinic for Pediatric Diseases – Skopje(Scientific Foundation SPIROSKI, 2020-06-10); ; ; <jats:p>BACKGROUND: The misuse and overuse of antibiotics contribute to the development of antimicrobial residence. Official data in EU/ EEA in 2017 in the hospital sector suggested that the consumption is lowest in the Netherlands, with 1 DDD per 1,000 inhabitants/day in comparison with Finland, with 2.8 DDD/TID. AIM: The aim of this study was to analyze data on the scope and structure of the antibiotic prescription in pediatric patients at University Children’s Hospital for period of 3 months in 2018 and 2019. MATERIALS AND METHODS: The data for antibiotic consumption were obtained from a hospital pharmacy, which are ordinated to hospitalized patients. RESULTS: The total amount of utilized antibacterial drugs with ATC code J01 for first quarter in 2018 is 33.65 DDD/100BD in comparison to the first quarter of 2019 when it declined to 32.09 DDD/100BD. The most consummated antibiotics in the first trimester of both years were the group of cephalosporins, especially the 3rd- and 4th-generation parenteral cephalosporins with from 16.96 to 19.25 DDD/100BD in the evaluated period. Decrease of penicillin’s, carbapenems, macrolides and quinolones were confirmed in the analyzed period. The most commonly used drugs remain ceftriaxone – 13.49 DDD/100BD in 2018 and increased to 14.41 DDD/100BD in 2019, followed by amikacin 3.21 DDD/100BD in 2018 and increased to 3.50 DDD/100BD in 2019 but azithromycin consumption significantly declined from 1.97 DDD/100BD to 0.81 DDD/100BD administered orally. The third most commonly utilized antibiotic in first quarter of 2019 become meropenem, antimicrobial drug from the group of carbapenems with 2.71 DDD/100BD. CONCLUSION: The benefits of monitoring the antibiotic prescribed pattern are critical due to the fact that they provide adequate data on consumption of antibiotics and adherence to guidelines.</jats:p> - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The ethical dilemmas in community pharmacy practice: quantitative study in Macedonia(Macedonian pharmaceutical association, 2022); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, AKR1D1*36 C>T (rs1872930) allelic variant is associated with variability of the CYP2C9 genotype predicted pharmacokinetics of ibuprofen enantiomers - a pilot study in healthy volunteers(Walter de Gruyter GmbH, 2019-09-01); ; ; ; Geskovska, Nadica MatevskaThe relative contribution of CYP2C9 allelic variants to the pharmacokinetics (PK) of ibuprofen (IBP) enantiomers has been studied extensively, but the potential clinical benefit of pharmacogenetically guided IBP treatment is not evident yet. The role of AKR1D1*36C>T (rs 1872930) allelic variant in interindividual variability of CYP450 mediated drug metabolism was recently elucidated. A total of 27 healthy male subjects, volunteers in IBP single-dose two-way cross-over bioequivalence studies were genotyped for CYP2C9*2, CYP2C9*3 and AKR1D1*36 polymorphisms. The correlation between CYP2C9 and AKR1D1 genetic profile and the PK parameters for S-(+) and R-(-)-IBP was evaluated. Remarkable changes in the PK values pointing to reduced CYP2C9 enzyme activity were detected only in the CYP2C9*2 allelic variant carriers. Statistically significant association between the AKR1D1*36 allele and the increased IBP metabolism (low AUC0-t and 0-∞, high Cltot and short tmax values for both enantiomers) was observed in subjects carrying the CYP2C9 *1/*3 or CYP2C9*1/*1 genotype. The clinical value of concomitant CYP2C9 and AKR1D1 genotyping has to be further verified. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Role and activities of pharmacists in RN Macedonia at the beginning of COVID-19 pandemic: March-April 2020(Macedonian pharmaceutical association, 2022); ; ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Hospital pharmacists as key factor for improvement of adverse drug reactions reporting practice, the Macedonian case(2019-05); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Community pharmacists in RN Macedonia at the frontline of COVID-19 pandemic beginning: March-April 2020(Macedonian pharmaceutical association, 2022); ; ; ;
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