Naunova Timovska, Silvana
Preferred name
Naunova Timovska, Silvana
Official Name
Naunova Timovska, Silvana
Alternative Name
Naunova Timovska Silvana
Timovska Naunova Silvana
Naunova Timovska S
Timovska N Silvana
Silvana Naunova Timovska
Silvana Naunova-Timovska
Naunova-Timovska S
Силвана Наунова -Тимовска
Силвана Тимовска-Наунова
Main Affiliation
Email
silvana.timovska@medf.ukim.edu.mk
32 results
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Item type:Publication, TROPONIN – OUR EXPERIENCE IN DETERMINATION OF MYOCARDIAL ISCHEMIC DAMAGE IN POSTOPERATIVE PERIOD OF CARDIAC SURGERY IN PEDIATRIC POPULATION(2017); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, NEONATAL ACUTE KIDNEY INJURY ASSOCIATED WITH COMORBID CONDITIONS(Medical Faculty, Ss. Cyril and Methodius University in Skopje, 2015)Acute kidney injury (AKI) is a common clinical problem in neonatal intensive care units. Predisposing factors are perinatal asphyxia, prematurity, sepsis, and congestive heart failure. The aim of this study was to determine the contributung conditions associated with neonatal acute kidney injury.Materials and methods. In a clinical prospective sudy we evaluated neonates with acute kidney injury who had been hospitalized in the NICU at University Childrens Hospitals in Skopje, Republic of Macedonia. We studied medical records of neonates with a diagnosis of acute kidney injury in the period 2013-2014. Results. Out of 450 hospitalized neonates, 29(6.4%) with a documented acute kudney injury were analyzed in the study. The male to female ratio was 2.6:1. Most of the neonates involved in the study were term neonates (66%). Prerenal AKI was evaluated in 80% of cases. Perinatal asphyxia was the most common predisposing factor for kidney injury in our study and was evaluated in 56% cases with predomination of term infants and male. Sepsis was present in 44% of cases, prematurity in 34%, and congenital malformations in 27% of cases. Mortality rate was 26% and it was significantly higher in patients with assisted ventilation and sepsis (p<0.05). Conslusion. Early recognition of risk factors and rapid effective tratment of contributing conditions will reduce acute kudney injury in neonatal period. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Depression Intensity in Patients with Schizophrenia(ID Design 2012, 2011); ; Background: Depressive symptoms are common in schizophrenia and they can occur during any phase of the disorder. Previous studies indicate that depression in schizophrenic patients is generally with mild or moderate intensity. Aim: We undertook this study with the aim of evaluation of the presence and intensity of the depressive symptoms in patients with schizophrenia. Material and Methods: The examined group consisted of 50 patients with schizophrenic disorder, both inpatients and outpatients treated at the University Clinic of Psychiatry, who had prominent depressive symptoms (total score >7 on 17-item Hamilton Depression Rating Scale). The control group consisted of 50 patients with depressive disorder. Differential diagnosis was established on the basis of ICD-10 diagnostic criteria. Patients were evaluated with PANSS, 17-item Hamilton Depression Rating Scale (HAMD) and a questionnaire for demographic and clinical data. Results: The percentage of patients with depressive symptoms among the patients with schizophrenic disorder was 54 %. Schizophrenic patients more frequently presented mild and moderate depression in comparison to the control group in which moderate and severe depression were more frequent. Conclusion: Patients with schizophrenia more frequently present mild and moderate depression. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Using Score for Neonatal Acute Physiology Perinatal Extension II (SNAPPE II) In Neonates with Acute Kidney Injury(ID Design 2012/Scientific Foundation SPIROSKI, 2019); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Neonatal acute kidney injury in intensive care unit in Republic of Macedonia(2017); V. TimovskiObjective: Acute kidney injury (AKI) is serious clinical problem in newborns in the neonatal intensive care unit (NICU). Predisposing factors for AKI in neonatal age are: certain clinical conditions (asphyxia, prematurity, sepsis, and meconium plug syndrome), therapeutic interventions and other nephrotoxic drugs. The aim of the study was to present the epidemiological and clinical characteristics of neonatal acute kidney injury in intensive care unit. Subjects & Methods: The study was designed as a prospective, clinical, epidemiological investigation conducted in the period of 3 years, which included 100 newborns hospitalized in NICU of University Children’s Hospital (50 with AKI and 50 without AKI). Мedical data records of admitted neonates with AKI were analyzed. The material was statistically processed using methods of descriptive statistics. Results: The estimated prevalence of AKI in neonates was 6.4%, according to the standard definition, while the prevalence of neonatal AKI according to RIFLE classification was 8.7%. According to pathogenetic mechanisms that lead to kidney injury, prerenal AKI prevailed and it was registered in 78% of male newborns with neoliguric type of AKI. Perinatal asphyxia was a common predisposing factor associated to neonatal kidney injury and it was found in 30% of the examined newborns, being predominant in male infants and born with a low Apgar score in the fifth minute of their life. There was a significant association between the occurrence of AKI and mechanical ventilation and aminoglycoside therapy. The mortality rate was 32% and was significantly higher in the group of newborns with congenital heart diseases. Conclusion: Acute kidney injury is a life threatening condition. It is an independent contributor to mortality. Early diagnosis and appropriate treatment of acute kidney injury in critically ill newborns, improves the outcome and prognosis. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, EVALUATION OF PROCALCITONIN AND SERUM ALBUIN LEVELS AS EARLY INFLAMMATORY BIOMARKERS IN NEONATAL SEPSIS(Medical Faculty, Ss. Cyril and Methodius University in Skopje, 2020); ; ; ; Kimovska MPrematurity is the leading cause of death globally, and the second largest contributor to all deaths under the age of 5. The aim of this study was to evaluate serum albumin levels and procalcitonin levels for the diagnosis and prognosis of preterm newborns with neonatal sepsis. In this study, we included 100 hospital admitted preterm newborns with the first 24 hours of life, hospitalized at the Intensive Care Unit at the University Children's Hospital-Skopje, for the time period between November 2018 until 30 April 2020. The preterm newborns have been divided into three groups according to albumin levels (>30, 25-30, or <25 g/l). There was a highly significant difference between the discharge diagnosis groups, regarding their serum albumin levels and Procalcitonin (PCT) levels, and there was a significant correlation between serum albumin level and PCT levels in preterm newborns, as well. Lower serum albumin levels might be associated with a poorer prognosis in neonatal sepsis. Serum albumin and procalcitoni levels have been proposed to be an early marker for the diagnosis of neonatal sepsis and a valuable follow-up tool. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, OSTEOMYELITIS OF FEMUR IN A DRUG ADDICTED CHILD(Macedonian Association of Anatomists, 2021); ; ; ; One of the serious complicationsrelated to intravenous drug use is osteomyelitis. We report a13-year-old male child with a history of intravenous heroin abuse, who was admitted to the hospital complaining of abdominal pain and pain in the left leg. Anteroposterior roentgenogram and CT scan of the left thigh and femur,confirmed the diagnosis of osteomyelitis. Pus culture was positive for Staphylococcus aureus. Despite extensive antibiotic and anticoagulant therapy,the patient’sclinical status improved very slowly. Surgical procedure was not undertaken. Femoral osteomyelitis due to injection drug use in childhood is an extremely rare and uncommoncondition. Intravenous drug abuse, late-onset treatment, and secondary bacterial infection can lead to complications which occurred in the case presented.Itis an extremely difficult condition to treat and is a real challenge for physicians. The rapid response and participation of a multidisciplinary team of physiciansis of particularimportance - Some of the metrics are blocked by yourconsent settings
Item type:Publication, HYDROCEPHALUS WITH VENTRICULOPERITONEAL SHUNT IN INFANTS: OUR EXPERIENCES AND CLINICAL OUTCOMES(Macedonian Association of Anatomists, 2022-12); ; ; Mica Kimovska-HristovAbstractHydrocephalus is a condition resulting from disorder in absorption and circulation of the cerebrospinal fluid (CSF). It leads toaprogressive ventricular dilatation and need of ventriculoperitoneal shunt (VP)placement. The aim of our study wasto present our experience withinfantswith hydrocephalus,ventriculoperitoneal shunt placement, and earlypostoperative follow-up.A retrospective study was conducted comprising infantswith hydrocephalus born between January 2019-January 2022with ventriculoperitoneal shunt placement performedatthe University Clinic for Neurosurgery in Skopje,Macedonia. Demographic and clinical characteristics, complications and the need for ventriculoperitoneal shunt were documented.Of twenty-three infantswith hydrocephalus,14 (60.8%) were preterm infants (median birth weight 2120g; mean gestational age 33.1weeks), 9(39.1%) were term infants(mean birth weight 3600g; mean gestational age 38.4 weeks). The etiology of hydrocephalus was:congenital hydrocephalusin 5infants(21.7%),prematurityin 6 infants(26.08%), spina bifida in 2 infants(8.7%),systemic infection in 4 infants(17.3%), and intraventricular hemorrhage in 6 infants(26.08%).Ventriculoperitoneal shunt was placed inall 23infants, at the mean age of 33.5(30-43) days.Postoperative complicationsas a result of ventriculoperitoneal shuntplacement were:ventriculitismanifested in3 preterm (13%) infants,of which 2(8.6%) died;fiveterm infants(21.7%) had postoperativeseizures, of which2 infants(8.6%) died. Nineteeninfants(82.6%) were discharged and transferredto the neonatology department. Ventriculoperitoneal shunt placementis atreatment of choice for infantswith hydrocephalus, although postoperative complications in preterm infantsincrease the percentageof morbidity and mortality. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, NEONATAL ACUTE KIDNEY INJURY IN INTENSIVE CARE UNIT(2017); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, DIAGNOSTIC VALUES OF BIOCHEMICAL MARKERSIN ASPHYXED NEWBORNS WITH PROVEN SEPSIS(Macedonian Association of Anatomists, 2020); ; ;