Hristomanova mitkovska, Slavica
Preferred name
Hristomanova mitkovska, Slavica
Official Name
Hristomanova mitkovska, Slavica
Main Affiliation
Email
slavica.hristomanova@medf.ukim.edu.mk
5 results
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Item type:Publication, Total IgE Distribution in Food Allergy Suspected Patients in Republic of Macedonia (2001-2011)(ID Design 2012/DOOEL Skopje, 2015-06-15); ; ; ; IgE may be considered the hallmark of allergic disorders. It is easily detected in serum and can be measured as total IgE and as allergen-specific IgE. In fact, the serum IgE assay is used to diagnose an allergy. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Distribution of Killer Cell Immunoglobulin-Like Receptor Genes in Albanians from Republic of Macedonia(ID Design 2012/Scienfitic Foundation SPIROSKI, 2015-02-19); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, HLA profile of the donors in the Macedonian Bone Marrow Donor Registry(Wiley Online Library, 2018-12); ; ; ; Aleksandar SenevThe importance of HLA alleles in the process of haematopoietic stem cell transplantation, especially the process of unrelated donor search, is enormous. Macedonian Bone Marrow Donor Registry was established in 2010 and has registered volunteer donors from different nationalities that live in the Republic of Macedonia. The aim of this study was to determine the HLA allele and haplotype frequencies of the volunteer donors from the Macedonian Bone Marrow Donor Registry and to compare this results with the Macedonians from a family study. We analyzed 1,541 donors, with different nationalities, Macedonian, Albanian and Macedonian Muslims that were most numerous in MBMDR, and typed them for HLA-A, -B, -C, -DRB1, whereas Macedonian also for HLA-DQA1 and HLA-DQB1 by SSO method (One Lambda, CA, USA). The most frequent alleles in Macedonians were HLA-A*02, 01, 24; HLA-B*35, 18, 51; HLA-C*07, 04, 12; HLA-DRB1*11, 16, 13; HLA-DQA1*01, 05 and HLA-DQB1*05, 03, 06; in Albanians they were HLA-A*02, 24,01; HLA-B*51, 18, 35; HLA-C*07, 04, 12, HLA-DRB1*11, 13,16; and in Macedonian Muslims they were HLA-A*02, 01, 24; HLA-B*18, 51, 35, HLA-C*07, 04, 02 and HLA-DRB1*11, 16, 14. The most common haplotype in Macedonian was HLA-A*01-B*08-C*07-DRB1*03, whilst in Albanian and Macedonian Muslims HLA-A*02-B*18-C*07-DRB1*11. The comparison of the HLA allele groups between Macedonian from MBMDR and family study showed similar distribution. This study confirmed the close relationship between the populations that live in the Balkan Peninsula. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Distribution of killer cell immunoglobulinlike receptors in the Macedonian population(Elsevier BV, 2010-03); ; ; Derek MiddletonThe aim of this study was to analyze killer immunoglobulinlike receptor (KIR) gene polymorphism in the Macedonian population. The study sample consists of 214 healthy unrelated individuals, aged 20-35 years. All individuals are of Macedonian origin and nationality, and residents of different geographic regions. The population genetics analysis package, Arlequin, was used for analysis of the data. We found that all 16 KIR genes were observed in the Macedonian population and framework genes KIR3DL3, KIR2DL4, and KIR3DL2 were present in all individuals. A total of 56 different KIR genotypes were found in the Macedonian population, based on the presence of 16 KIR genes. Neighbor-joining phylogenetic tree, constructed on the basis of standard genetic distances of KIR genes, shows that Macedonian population is in the same cluster with England West Midlands Indian Asian, Brazil SouthEast Caucasian, Romania Caucasians, Spain Basque, England West Midlands Caucasian, France Reunion, and Spain Granada populations. The frequency of KIR loci in Macedonian population shares several general features with other Caucasoid populations studied before. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Перфорација на очното јаболко по минимална траума кај пациент со Ехлер-Данлос-ов синдром-приказ на случај(SHMSHM - AAMD, 2012-12); ; ;