Vrajnko, Elif

Preferred name

Vrajnko, Elif

Official Name

Vrajnko, Elif

Now showing 1 - 10 of 16

Some of the metrics are blocked by your
consent settings
Mycotic aortic aneurysm and endocarditis
(National Society of Cardiology of N. Macedonia, 2022-11)
Bede I
;
Chaparoska E
;
Otljanska M
;
;
Taravari H
Some of the metrics are blocked by your
consent settings
Paget Schroetter Syndrome - Case report
(National Society of Cardiology of N. Macedonia, 2022-11)
Kostova N
;
Otljanska M
;
Zafirovska-Taleska B
;
Kostov I
;
Andova V
Some of the metrics are blocked by your
consent settings
Case report: Patient with ventricular septal defect following acute myocardial infarction
(National Society of Cardiology of N. Macedonia, 2022-11)
Trajkova M
;
Eftimova A
;
;
Andova V
Some of the metrics are blocked by your
consent settings
Учество во GHATI(Globalhear Atack Threatment iniatiative), Регистерот како евалуација на третманот на миокарден инфаркт
(Македонско здружение по Кардиологија, 2021-10)
Igor Zdravkovski
;
;
Elma Kandikj
;
Oliver Bushletikj
;
Some of the metrics are blocked by your
consent settings
Left ventricular systolic function in patients with acute coronary syndrome-risk profile
(Oxford University Press (OUP), 2024-04)
Dobjani, A
;
Bogevska Naumovska, I
;
;
Shehu, E
;
Taravari, H
Introductions and objectives Left ventricular (LV) systolic dysfunction is one of the most important determinants of long-term outcome in acute coronary syndrome (ACS). Aim To determine the impact of the patient’s risk profile on the LV systolic function. Methods A single-center cross-sectional cohort study that included 3093 patients with ACS without pre-existing LV dysfunction. The comparison was performed between patients who did or did not develop a reduction in LV systolic function during the index event (<50%/≥50%), analyzing patients’ demographic, clinical, biochemical data, LV functional data, and anatomical distribution of the coronary artery disease (CAD). Result 1369 patients out of 3093 developed LV systolic dysfunction (44.3%). They were predominantly males 75.1% (1028), p=0.002; older (63.39±11.04 vs 61.21±11.12, p<0.00000); had higher level of cardiac troponin (p=0.00002), higher stress glycemia (9.2±5.3; p=0.0000001), HbA1c (6.9±1.8, p=0.000003), WBC (11.7±4.1, p=0.00001), blood urea nitrogen (BUN) (6.8±3.7, p=0.000003), and creatinine (93.2±45.1 p=0.000167), and had anemia (OR 0.35 (CI 0.29–41, p=0.000012). They had more severe CAD (SINTAX score 16.8±8.4 p=0.000012). Patients with preserved LV systolic function were predominantly females (29.7%, OR 1.1 95% CI 1.0-1.2), p = 0.002), younger (p<0.00000), and severely metabolically burdened (hypothyreosis (2.7%, OR 1.28 95% CI 0.93-1.76, p=0.052), higher levels of triglycerides (2.2±1.7 vs 1.9±1.5, p = 0.001), cholesterol (5.3±1.4 vs 5.2±1.4, p = 0.002), non-HDL-C (4.1±1.5 vs 3.9±1.3, p=0.006), however less likely to have pre-existing DM (OR 0.8 (CI 0.78–0.92), p=0.000094). They were more often NSTEMI [851 (49.4%), p = 0.000012]. Independent variables associated with a reduction in LV function were: advanced age, male gender, previous DM and anemia, stress glycemia, WBC, creatinine, and BUN. Conclusion Patients who developed reduced LV function had a very specific risk profile with bigger neuro-hormonal activation and inflammation, higher degree of myocardial damage, and worse renal function, whereas those with preserved LV systolic function after ACS were younger, predominantly females, more severely metabolically burdened, more often with NSTEMI and without LAD involvement.
Some of the metrics are blocked by your
consent settings
One-year post-Covid-19 follow up
(Macedonian Association of Internal Medicine, 2022-05)
;
Eftimova A
;
Trajkova M
;
;
Bushljetikj O
Some of the metrics are blocked by your
consent settings
A case of myocardial infarction in a young patient with combination of factor V Leiden and MTHFR gene mutation
(National Society of Cardiology of N. Macedonia, 2022-11)
;
Zafirovska B
;
Dimitrovska B
;
Bede I
;
Tomeski S
Introduction: Inherited thrombophilia due to a combination of factor V Leiden and MTHFR gene mutation leads to a hypercoagulable state resulting in thromboembolic events and arterial thrombosis. Case report: We present a case of a 35-year-old male patient who presented to the emergency room with intensive chest pain that started 2 hours ago while he was cycling for a distance of 11km. The ECG showed ST segment elevation of 3mm in the inferior leads. An emergent coronary angiography was indicated which showed thrombotic formations in the proximal right coronary artery (RCA), rPDA and RPL without atherosclerotic plaques. Percutaneous coronary intervention with plain old balloon angioplasty (PCI/ POBA) and thromboaspiration was performed, which was followed by tirofiban infusion and continuous infusion of unfractionated heparin for 24 hours. The molecular genetic analysis revealed the patient to be heterozygous for factor V Leiden and homozygous for methylenetetrahydrofolate reductase (MTHFR) C677T gene mutation. After completing the required clinical examinations, the patient was discharged in a good clinical condition with a recommendation for medical treatment including a prophylactic dose of direct oral anticoagulant. After a one-year follow-up, the patient had no symptoms or recurrent cardiovascular events. Conclusion: Inherited thrombophilia is а significant risk factor for coronary artery disease and performing genetic testing in younger patients with a cardiovascular event, plays an important role for adequate treatment and prophylaxis from recurrent complications. Although individual patient consideration is recommended, the use of oral anticoagulation for prophylaxis is shown to be effective in these patients. However, further studies are needed for the indications and duration of prophylactic anticoagulation in patients with inherited thrombophilia after an arterial thrombotic event.
Some of the metrics are blocked by your
consent settings
А rare case of left ventricular hypertrophy and non-compaction cardiomyopathy in an adult: diagnostic approach
(Macedonian Society of Cardiology, 2021-03)
;
Zafirovska, P
;
Risteski, D
;
;
Left ventricular non-compaction cardiomyopathy (LVNC) is a rare form of primary genetic cardiomyopathy which is characterized by prominent trabeculations and intertrabecular recesses that communicate with the cavity of the left ventricle. The prevalence is between 0.014%-1.3% in the general population. LVNC is associated with different genetic mutations and may have a genetic overlap with the phenotype of other cardiomyopathies, including hypertrophic cardiomyopathy (HCM). In this case report we present a 26-year-old female patient presenting to emergency room with bradycardia and syncope. The transthoracic echocardiography revealed hypertrophy and trabeculations with prominent recesses of the left ventricle. Cardiovascular magnetic resonance imaging (MRI) was performed to confirm the diagnosis of LVNC. The genetic analysis showed mutation of PRKAG2 gene indicating hypertrophic cardiomyopathy with conduction disturbance. In the last years, LVCN and HCM are diagnosed more frequently due to improvements in imaging methods. Although there are many diagnostic tools including contrast ventriculography, CT and MRI, echocardiography is the main imaging method used for diagnostic evaluation of LVNC and HCM. Key words: left ventricular non-compaction cardiomyopathy, hypertrophic cardiomyopathy, echocardiography, cardiovascular magnetic resonance imaging
Some of the metrics are blocked by your
consent settings
Early coronary artery disease (CAD) in a female patient with discoid lupus erythematosus (DLE) and Hashimoto's thyroiditis
(National Society of Cardiology of N. Macedonia, 2022-11)
Dimitrovska B
;
Jovchevska S
;
Bede I
;
;
Kostova N
Some of the metrics are blocked by your
consent settings
Acute Myocarditis after Pfizer-BioNTech COVID-19 m-RNA Vaccination
(Scientific Foundation SPIROSKI, 2022-11-30)
Elena Grueva-Nastevska
;
;
Planinka Zafirovska
;
Elma Kandic
;
BACKGROUND: Prosthetic mechanical valve endocarditis (PVE) can be manifested as early PVE (acquired perioperatively) and late PVE (resulting from infections unrelated to the valve operation). Causes of both are similar but are late PVE are more prone to less virulent microbes. PVE resulting with paravalvular abscess is confirmed through echocardiography (transthoracic or transesophageal), it results with a high mortality rate especially if it is not early recognized. CASE PRESENTATION: We are presenting a patient with heart failure symptoms caused by PVE after Pfizer-BioNTech coronavirus disease-2019 (COVID-19) m-RNA vaccination. CONCLUSION: The exact mechanism of myocarditis in young men who received the second dose of mRNA COVID-19 vaccine is not yet known. However, this is a rare complication and most people generally recover quickly requiring only supportive treatment. In contrast, the risk of developing myocarditis from the viral infection is much higher.

Vrajnko, Elif

Filters

Settings

Sort By

Results per page