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    STENT THROMBOSIS IN REAL WORLD REGISTRY PATIENTS
    (Macedonian Association of Anatomists, 2018)
    Trajceski, Ted
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    Brovina, L
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    Tertiary Lymphoid Structures in Colorectal Cancers and Their Prognostic Value
    (ID Design 2012/DOOEL Skopje, 2018-10-25)
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    Karadzov, Zoran
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    Hadzi-Manchev, Dragan
    Tumor-infiltrating lymphocytes (TIL) in tumour stroma are considered to be involved in the elimination of malignant cells and prevention of metastasis formation. TIL consist of T lymphocytes including cytotoxic lymphocytes that are a constituent part of the effector mechanism of anti-tumour immunity and B lymphocytes that can form tertiary lymphoid structures (TLS). TLS has been described in several solid tumours and colorectal carcinoma (CRC), and the influence on the local and systemic anti-cancer response.
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    Low-grade malignancy glomus tumor of the abdominal wall: a case report and literature review
    (Oxford University Press (OUP), 2023-12)
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    Gelevski, Radomir
    Glomus tumors are painful neoplasms arising from the glomus body (responsible for body temperature and blood pressure regulation) in the skin. Although mostly present in the interdigital areas, glomus tumors can arise elsewhere. The vast majority of them are benign. Rarely, malignant variants are reported and are associated with the potential for local infiltration and metastatic dissemination. The abdominal wall location of glomus tumors is extremely rare regardless of whether they present as benign or malignant. We present a case of a 58-year-old female patient with a low-grade malignancy infiltrative glomus tumor of the abdominal wall.
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    Role of urinary podocalyxin in early diagnosis of diabetic nephropathy
    (Sciendo, 2020-08-10)
    Irena Kostovska
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    P1000 ALLERGY IN CHILDREN WITH GASTROESOPHAGEAL REFLUX AND RESPIRATORY DISEASE
    (Ovid Technologies (Wolters Kluwer Health), 2004-06)
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    Kostovski, A
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    Giant retroperitoneal low grade liposarcoma with left kidney displacement: A case report
    (Elsevier BV, 2022-11)
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    Retroperitoneal liposarcomas are diagnostic and therapeutic challenge due to their expansive growth and tendency for recurrence. They represent the most of the sarcomas of the retroperitoneal space with the incidence of 41%. Most of them can grow in large proportions before symptom occurrence and change the anatomy of the retroperitoneum. Computerized tomography remains the main diagnostic tool in such cases that provides precise tumor location, size and relation to the adjacent organs. Surgery is the method of choice for treatment. Nevertheless, they tend to recur in 50%-80% of patients despite the appropriate surgery. We present a case of giant retroperitoneal liposarcoma in a female patient with significant left kidney displacement that recurred within 5 years of its removal.
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    High expression of CD133 - stem cell marker for prediction of clinically aggressive type of colorectal cancer
    (Fundacja Polski Przegląd Chirurgiczny, 2020-04-14)
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    Irena Kostovska
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    Background: Colorectal cancer (CRC) is one of the most common malignancies in the world. The cancer stem cell (CSC) markers are associated with aggressive cancer types and poor prognosis. The objective of study was to evaluate the CD133 expression and to correlate it with clinicopathological futures in patients with CRC. Material and Methods: Our study included ninety patients with CRC who underwent curative surgical resection from 2012 to 2017 at the University Clinic for Digestive Surgery, Skopje, North Macedonia. Tumor samples first were analyzed with standard histopathological methods and than CD133 expression was investigated immunohistochemically. The level of expression of CD133 was classified semiquantitatively. Low positivity was defined as positive immunoreactivity in < 50% of tumor glands, and high positivity was defined as positive immunoreactivity in ≥ 50% of tumor glands. Furthermore, clinicopathological futures of patients was retrospective reviewed. Results: High expression of CD133 was found in 47, 8% of patients CRC samples. In 69, 6% of patients with metastatic lesions in visceral organs we found high expression of CD133. We found statistically significant differences in expression of CD133 between patients with and without visceral metastatic lesions (p = 0, 0153), between patients with different T category ((p=0,0119), N-status (p=0,0066) and G-differentiation (p=0,0115). Our results showed that the stage of disease has the greatest impact on expression of CD133 (p <0.00001). Conclusion: High expression of CD133 is useful marker for prediction of clinically aggressive type of CRC and can be routinely implemented in standard pathohistological diagnostics.
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    ПРЕДИЗВИЦИ НА ЛАПАРОСКОПСКАТА ПОПРАВКА НА ИНГВИНАЛНА ХЕРНИЈА
    (SHMSHM, 2013-05)
    Александар Митевски
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    Кемал Рушити
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