Now showing 1 - 10 of 24
  • Some of the metrics are blocked by your 
    Item type:Publication,
    The Effect of Rectus Sheath Block as a Supplement of General Anesthesia on Postoperative Analgesia in Adult Patient Undergoing Umbilical Hernia Repair
    (Walter de Gruyter GmbH, 2017-12-01)
    ;
    ;
    ;
    Zdravkovska, Milka
    ;
    Ultrasound guided rectus sheath block can block the ventral rami of the 7th to 12th thoracolumbar nerves by injection of local anesthetic into the space between the rectus muscle and posterior rectus sheath. The aim of this randomized double-blind study was to evaluate the analgesic effect of the bilateral ultrasound guided rectus sheath block as supplement of general anesthesia on patents undergoing elective umbilical hernia repair.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Accidental injection of succinylcholine into epidural space as a test dose
    (Wolters Kluwer – Medknow, 2020)
    Toleska, Marija
    ;
    ;
    Dimitrovski, Aleksandar
    Inadvertent injection of nonepidural drugs into the epidural space is a rare situation, which is under-reported, and can lead to serious complications, such as cardiovascular and respiratory complications, paraplegia, or quadriplegia, and can worsen the patients' outcome from surgery. Succinylcholine administered epidurally leads to the appearance of fasciculation and shortness of breath and can prolong neuromuscular blockade. We report a case of accidental administration of 100 mg of succinylcholine via an epidural catheter as a test dose instead of 2 ml 0.5% bupivacaine in a patient planned for major abdominal surgery. After 2 min, the patient complained of shortness of breath; dysarthria; and fasciculation in the trunk, upper limbs, and face. This was managed with induction to general anesthesia (GA). In the postoperative period, no neurological or cardiovascular complications were observed. There is no adequate drug as an antidote of accidentally given nonepidural drugs via an epidural catheter. Succinylcholine given via epidural catheter has been shown to prolong neuromuscular blockade. Proper labeling and storage of syringes are of utmost importance for avoiding these unpleasant situations.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Acute hyponatriemia in a patient with schizophrenia: Case report water intoxication induced acute hyponatriemia
    (Udruženje anesteziologa i intenzivista Srbije, Beograd, 2019)
    ;
    ;
    ;
    Trposka, Angela
    ;
    Stojkovska, Ana
  • Some of the metrics are blocked by your 
    Item type:Publication,
    LUNG ULTRASOUND DERIVED INSIGHTS IN VENTILATOR ASSOCIATED PNEUMONIA
    (Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R.N. Macedonia, 2024)
    ;
    ;
    ;
    ;
    Toleska, Marija
    Lung Ultrasound (LUS) is widely used in diagnosis and monitoring of Ventilator Associated Pneumonia (VAP). The aim of our study is to evaluate and detect local lung events in mechanically ventilated patients, as well as to evaluate the usage of LUS in distinguishing VAP from Ventilator associated tracheobronchitis. We examined LUS finings in all patients who fulfilled the criteria for VAP, and stratified them according to the CLUE Protocol. We have examined the findings for VPLUS Score of each patient and tried to find a correlation between LUS Score and VPLUS Score. The average value of total LUSS of all patients examined was 11.05. LUS Score of the upper segments versus lower segments was 0.07 versus 2.1 respectively with 95% CI from 1.44 to 2.61, and significance level p<0.0001 suggesting the existence of statistically significant difference into distribution of pathological findings in between upper versus lower lung segments. Also, we found a LUS Scores difference of 3.46 with 95%CI of 0.95 to 5.96 and significance level of p=0.0099 which implies existence of statistically significant higher LUS Score values in patients with VPLUS >2 versus patients with VPLUS of 2. In conclusion, the pathological findings in patients with VAP were distributed in the dependent regions, while upper segments were spared. Also, only patients with VPLUS>2 instead of VPLUS≥2 should be considered as having VAP.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    USE OF DESFLURANE: CONSIDERATIONS AND CONTROVERSIES
    (Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R.N. Macedonia, 2024)
    ;
    ;
    Desflurane stands as a pivotal volatile anesthetic in contemporary anesthesia practice and has been a cornerstone of modern anesthesia practice due to its rapid onset and offset of action. Despite its clinical advantages, the environmental footprint of desflurane, characterized by significant greenhouse gas emissions, has sparked a debate on its continued use and potential regulatory measures. This article evaluates desflurane’s clinical benefits, alongside its environmental implications, offering insights into possible regulation perspectives. Highlighting its favorable pharmacokinetic properties, rapid induction, hemodynamic stability and bronchodilator effects, against its contribution to climate change, the study aims to foster a balanced discourse on desflurane’s role in healthcare, advocating for a harmonization of clinical needs with ecological stewardship.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
    (Springer Science and Business Media LLC, 2020-10-09)
    Labeau, Sonia O.
    ;
    Afonso, Elsa
    ;
    Benbenishty, Julie
    ;
    Blackwood, Bronagh
    ;
    Boulanger, Carole
    Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score < 19, ICU stay > 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    TACHYCARDIA - BRADYCARDIA SYNDROME IN A PATIENT UNDERGOING PERTROCHANTERIC FRACTURE REPAIR UNDER SPINAL ANESTHESIA
    (Department of Anesthesia and reanimation, Faculty of Medicine, "Ss.Cyril and Methodius", University Skopje Macedonia, 2018-12)
    ;
    ;
    ;
    ;
    Trposka A
    Background: Sick sinus syndrome (SSS) is an abnormality of a cardiac impulse formation as a result of sinus node dysfunction that could be presented as a diverse heart rate and rhythm abnormalities. SSS is the most common in the elderly people. In most of the cases the etiology of the SSS remains unknown, but the majority of the patients are experiencing some stage of coronary artery disease (1). Case Report: We present an 89 years old female patient undergoing pertrochanteric fracture repair under spinal anesthesia. Her preoperative evaluation did not reveal any pathologic findings. All vital signs were stable prior to the surgery. The patient has received 2.4 ml of Bupivacaine 0.5% and 10 mcg of Fentanyl. Dural puncture was done in an aseptic technique at the L3-L4 level and clear liquor was seen prior to the anesthetic application. The first hour of the surgery went uneventful, after what abrupt onset of tachycardia of 109bpm was seen followed by bradycardia of 48bpm. The episodes of tachycardia followed with bradycardia were repeating till the patient entered a bigeminy rhythm with the lowest hearth rate of 45, after what 0.5 mg of atropine was given and restoration of normal sinus rhythm was seen. The patient was monitored postoperatively in PACU and followed up at the Traumatology ward while there were not seen any vital signs deterioration. Discussion: We’ve researched PubMed from 1994-2017 and we’ve found 8 case reports in patients undergoing general anesthesia, one undergoing general and epidural anesthesia and one under spinal anesthesia. Eight of 10 patients were previously healthy without known cardiac disease and one with peripheral artery disease. Different types of conduction and heart rate abnormalities, including asystole, were seen in all of the cases after induction of the patients under anesthesia. In our case during the surgery the patient developed multiple episodes of tachycardia followed with bradycardia without subjective discomfort. The resolution of the tachycardia-bradycardia syndrome after giving the 0.5 mg of atropine shows a possible relationship between the local anesthetic application and the onset of the SSS manifestation. References: 1. Brignole M1.; Sick sinus syndrome; Clin Geriatr Med. 2002 May;18(2):211-27. Learning points: SSS can be precipitated perioperatively because of increased vagal tone caused by anesthesia or surgical intervention. As general anesthetics, local anesthetics could also trigger intraoperative manifestation of SSS.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    THE ROLE OF INTRAOPERATIVE ECHOCARDIOGRAPHY IN ANESTHETIC MANAGEMENT OF A COMPLEX ABDOMINAL AORTIC ANEURYSM REPAIR: A CASE REPORT
    (Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R.N. Macedonia, 2024)
    ;
    Dimovska, Magdalena
    This case presents highlights of the role of intraoperative echocardiography in the successful management of a 65-years-old male scheduled for abdominal aortic aneurysm (AAA) repair. The patient was presented with an abdominal aortic aneurysm with multiple comorbidities and recent myocardial infarction with post stenting hemopericardium, making the anesthetic management for the surgical intervention challenging. Intraoperative echocardiography played a crucial role in establishing decisions about the treatment and guiding therapy for ensuring a favorable outcome. This report emphasizes the significance of intraoperative echocardiography as a real time monitor of hemodynamics in enhancing patient’s safety and favorable clinical outcomes during high-risk surgical procedures.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    "DEVELOPMENTAL HEMOSTASIS" AND PEDIATRIC SURGERY
    (Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R.N. Macedonia, 2023-12)
    ;
    ;
    Nancheva Bogoevska, Andrea
    ;
    Hemostasis can be defined as a physiological process that stops bleeding after injury of blood vessels. It is a complex and highly regulated process to localize the blood clot only to the site of injury. The hemostatic system in the human body is based on the components of Virchow’s triad: 1. vascular injury, 2. change in blood coagulability, 3. disturbance of blood flow (stasis). If the third component (blood flow) is excluded, hemostasis can be defined as an inter-reaction between the blood vessel wall, blood cell components and plasma proteins that maintain the hemostatic balance. The final outcome of hemostasis is coagulation of blood at the site of vascular injury(1,3). Hemostasis can be divided into primary, secondary and tertiary hemostasis. These three independent mechanisms combine to maintain hemostatic balance.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    ANESTHETIC MANAGEMENT OF PATIENT WITH SYSTEMIC SCLERODERMA SCHEDULED FOR RIGHT LOWER LOBE RESECTION OF THE LUNG
    (Department of Anesthesia and reanimation, Faculty of Medicine, Ss. Cyril and Methodius University, Skopje Macedonia, 2020-04)
    Trposka Poposka A.
    ;
    ;
    ;
    ;
    Progressive systemic sclerosis (PSS) or scleroderma is rare progressive fibrotic disorder of the connective tissue. Together with the connective tissue changes, atrophy of the skin, the involvement of various internal visceral organs may be present in these patients, as well. Not rarely, involvement of the alimentary tract, lungs, heart, kidney, CNS, the presence of the autoantibodies, collagen deposition on different body parts, together with the possible profound vascular hypersensitivity, are reported separately and in combination as possible anesthesiology challenges, sometimes even reported with detrimental outcome. We present a case of a successful anesthesiology management of a patient with PSS undergoing thoracic surgery and we discuss facts from the literature about this disease’s issues and anesthesi