Kaftandjieva, Ana
Preferred name
Kaftandjieva, Ana
Official Name
Kaftandjieva, Ana
Alternative Name
Kaftandzieva A.
Kaftandjieva A.
Кафтанџиева А.
A. Kaftandјieva
A. Kaftandzieva
А. Кафтанџиева
Kaftandzieva, Ana
Кафтанџиева, Ана
Ana Kaftandjieva
Ana Kaftandzieva
Ана Кафтанџиева
Main Affiliation
Email
ana.kaftandzieva@medf.ukim.edu.mk
43 results
Now showing 1 - 10 of 43
- Some of the metrics are blocked by yourconsent settings
Item type:Publication, COMPARISON OF THE SUSCEPTIBILITY OF ESBL-POSITIVE AND ESBL-NEGATIVE ISOLATES OF E. COLI AND KLEBSIELLA PNEUMONIAE TO ANTIMICROBIAL AGENTS(Macedonian Association of Anatomists and Morphologists (MAAM), 2014); ; ; The aim of this investigation was to compare the susceptibility between ESBL-positive and ESBL-negative isolates to different antimicrobial agents. Material and methods: A total of 1207 consecutive non-repeat isolates of E. coli and K. pneumoniae-Kp (E. coli-804, Kp-403) were obtained from different clinical specimens from patients hospitalized at the University Clinics in Skopje over a one year period. Conventional microbiological procedures for the isolation and detection of the strains were used. Susceptibility to beta-lactams and non-beta-lactams was determined by standard disk diffusion method and by automated method using Vitek (for determination of the MIC-minimal inhibitory concentration). A total of 251 isolates were selected (E. coli-126 and K. pneumoniae-125) using tests for phenotypic detection of the ESBL-production. A total of 233 randomly selected strains which were ESBL-negative by phenotypic tests (E.coli-130 and K.pneumoniae103) were used as a control strains for susceptibility testing. Results: Difference of the susceptibility to imipenem between ESBL-positive and ESBL-negative strains of E. coli and K. pneumoniae was not detected. Both groups of strains were 100% susceptible to imipenem. Considering the rest of the tested beta-lactams, as well as non-beta lactams and uroantiseptics, there was a difference in the susceptibility comparing both groups of strains of E. coli and K. pneumoniae. This was due to the fact that ESBL-negative strains were highly susceptible to all tested antimicrobial agents, unlike the ESBL-positive ones (except in cases of cotrimoxazole and nitrofurantoin, where the difference in susceptibility between ESBL-positive and ESBL-negative strains of E. coli was not statistically significant, because both groups of strains were susceptible to those antimicrobial agents).These data are important for recommending adequate treatment of infections with ESBL-producing bacteria. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The most common bacterial isolates from wound samples – a three-year study(INSTITUTE OF PUBLIC HEALTH OF REPUBLIC OF NORTH MACEDONIA, 2021); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Microbiological analysis of wound samples(Medical Faculty, Ss. Cyril and Methodius University in Skopje, 2020); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Incorporation of antimicrobial agents can be used to enhance the antibacterial effect of endodontic sealers(Elsevier, 2013-03); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, FREQUENCY OF SURGICAL SITE INFECTIONS FOLLOWING SURGICAL TREATMENT OF ISOLATED FRACTURES: A RETROSPECTIVE STUDY(Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, 2024); ; Kacarska, AleksandraSurgical site infections (SSIs) are a frequent and serious complication that occur after surgical treatment of isolated fractures, leading to increased morbidity, mortality, prolonged hospital stays, and higher healthcare costs. This study aimed to identify the frequency and risk factors associated with SSIs. Methods: This retrospective observational study included 51 patients who underwent open reduction and internal fixation (ORIF) surgery for isolated fractures and later developed bacterial infections. We analyzed factors such as the presence of comorbidity, patient age, gender, body region affected, and duration of the operation. We used multinomial logistic regression and chi-square tests as statistical analyses to examine the relationships between these factors and the types of pathogens as a cause of bacterial infection, classified as Gram-positive bacteria only, Gram-negative bacteria only, or both. Results: Our study found that in 18%, 56% and 26% of patients the cause of infection was Gram-positive, Gram-negative and both groups of bacteria, respectively. The factors that did not significantly predict the type of bacterial infection were: comorbidity presence, although the observed trends suggested further investigation was needed; duration of operation; and patient age. Gender analysis concluded a marginally significant association, with males less likely to have infections caused by Gram-positive bacteria. Additionally, the body region affected showed a marginally significant correlation with infection type, with the thigh region being more sensitive to infections caused by Gram-negatives. Our study highlights trends and marginal associations in SSIs post-ORIF surgery, suggesting the need of personalized infection control strategies. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Pneumococcal serotypes and their resistance to penicillin(Faculty of Medicine, Ss. Cyril and Methodius University, Skopje, R Macedonia, 2014); ; ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Phenotypic and genetic relationship of Acinetobacter Baumannii isolates(Македонска академија на науките и уметностите, Одделение за биолошки и медицински науки = Macedonian Academy of Sciences and Arts, Section of Biological and Medical Sciences, 2011); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Evaluation of Multiplex PCR in diagnosis of invasive infections with Candida species(Medical Facilty, Ss Cyril and Methodius University, Skopje, R Macedonia, 2016); ; ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Adenoid Vegetations - Reservoir of Bacteria for Chronic Otitis Media with Effusion and Chronic Rhinosinusitis(Македонска академија на науките и уметностите, Одделение за медицински науки = Macedonian Academy of Sciences and Arts, Section of Medical Sciences, 2015); ; Beti ZafirovskaIntroduction: Otitis media and rhinosinusitis are commonly encountered illnesses in pediatric population. Literature reports have documented the association between the occurrence of these two conditions and even their almost identical microbiological findings. Until recently, the key factor in the association of these two conditions was considered to be the hypertrophic adenoid tissue, but within the past few years there have been evidences in the literature about the presence of bacterial biofilms on the adenoids suggesting biofilms to be also responsible for both conditions, chronic otitis media with effusion and chronic rhinosinusitis. Aim: The aim of this study was to make a microbiological analysis of the adenoid tissue specimens taken from patients with chronic otitis media with effusion and chronic or recurrent rhinosinusitis and to determine their potential for biofilms formation. Methods: After the surgical intervention, adenoidectomy, microbiological evaluation and analysis of the adenoid tissue specimens taken from 20 patients were made. Having in mind the disease history, chronic otitis media with effusion was diagnosed in all 20 patients and chronic rhinosinusitis in 9 patients. Results: The results obtained from the microbiological analyses showed many potentially pathogenic bacteria in the adenoids that were almost identical with the most common organisms incorporated in the etiopathogenesis of both conditions, in chronic otitis media with effusion and in chronic rhinosinusitis. In 7 (35%) patients Haemophylus influenzae was isolated, in 6 (30%) Streptococcus pneumoniae, in 4 (20%) Moraxella catаrrhalis, in 2 (10%) patients Staphylococcus aureus and in 1 (5%) patient Streptococcus pyogenes - group A was isolated. One bacterium was isolated from all adenoid vegetations, except in one case when two bacteria (Haemophylus influenzae and Staphylococcus aureus) were concurrently isolated. Conclusion: Our results have shown that the key role in adenoid vegetations in chronic otitis media with effusion and chronic rhinosinusitis is not only the mechanism of rhinopharyngeal obstruction, but also the presence of bacterial strains with a large potential for formation of biofilms adhered to their surface, especially in cases with symptoms of chronic otitis media with effusion and chronic rhinosinusitis that were resistant to antibiotic therapy. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Phenotipic and genetic relationship of Acinetobacter baumannii isolates(Macedonian Academy of Sciences and Arts, 2011); ; ;