Trajkov, Dejan
Preferred name
Trajkov, Dejan
Official Name
Trajkov, Dejan
Main Affiliation
Email
dejan.trajkov@medf.ukim.edu.mk
59 results
Now showing 1 - 10 of 59
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Item type:Publication, The influence of the iodinate contrast medium during CT: Single center experience - Development of two competitive in-house methods for automated quantification of DDSB(Macedonian Pharmaceutical Association, 2019); ; ; Kroneis, ThomasDNA damage induced by ionizing radiation may ultimately lead to cell death or initiate cancer cells development. Today it is difficult to estimate what the actual damage to the human body will be, given the fact that today in the world the number of diagnostic procedures using radiation and iodine contrast media is increasing, and the existence of a number of factors that can affect the radiation dose in vivo. At the same time, development of new methods is required, which can determine in a much shorter time what will be the effect of diagnostic radiation on the DNA molecule. For these purposes we develop two competitive inhouse methods for automated quantification of DNA double strand brakes (DDSB) in peripheral blood lymphocytes: immunofluorescence determining of γH2AX with stained microscopic slides and determining the occurrence of DDSB with the flow cytometry. Our initial results shown that computed tomography (CT) can cause damage in the DNA molecule in the form of DDSB, the existence of linear dependence with the increase in low and high range of CTDI and the number of γH2AX, and that iodine contrast media can increase the occurrence of DNA double strand brakes. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Total IgE Distribution in Food Allergy Suspected Patients in Republic of Macedonia (2001-2011)(ID Design 2012/DOOEL Skopje, 2015-06-15); ; ; ; IgE may be considered the hallmark of allergic disorders. It is easily detected in serum and can be measured as total IgE and as allergen-specific IgE. In fact, the serum IgE assay is used to diagnose an allergy. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Association between 22 cytokine gene polymorphisms and dilated cardiomyopathy in Macedonian patients(2009-11); ; Inflammation is an important component in the pathogenesis of many cardiovascular diseases and one of the commonest mechanisms in cardiomyopathy. There have been several studies on the cytokine polymorphism and dilated cardiomyopathy (DCM), but the results obtained were contradictory. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Gene polymorphisms of 22 cytokines in Macedonian children with atopic dermatitis(2012-03); ; Atopic dermatitis (AD) is a common chronically relapsing skin disease associated with abnormal cytokine production, and activation of T-helper 2 cells. The aim if this study was to determine whether cytokine gene polymorphisms might influence the development of AD. Single nucleotide polymorphisms in the genes for I-L1alpha, IL-1beta, IL-1R, IL-2, IL-4, IL-6, IL-10, IL-12, TGF beta, TNF and IFNgamma were investigated by PCR and sequence specific primers in Macedonian patients with AD (67 children, age of 6 months to 5 years) and 301 normal unrelated individuals. Susceptible cytokine polymorphisms for AD for eleven genotypes (IL-4 -33/T:T IL-4 -1098/G:G, TGFbeta cdn25C:G, IL-4 -1098/T:T, IL-1alpha -889/C:T, IL-2 +166/T:T, IL-1beta -511/C:T, IL-12 -1188/C:T, IL-10 -1082/A:G, IL-1beta +3962/C:T, IFNgamma +874/A:T), five diplotypes, six haplotypes, and for alleles were found. Protective cytokine polymorphisms for AD for seven cytokine genotypes (IL-4 -1098/G:T, TGFbeta cdn25/G:G, IL-4 -33/C:C, IL-1alpha -889/C:C, IFNgamma +874/A:A, IL-10 -1082/A:A, IL-1beta -511/C:C), one cytokine diplotypes, two cytokine haplotypes, and four cytokine alleles were also found. We concluded that several cytokine polymorphisms are protective, or susceptible associated with AD in population of Macedonians. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, PREVALENCE OF ANTI-SARS-COV-2 IGG ANTIBODIES IN SKOPJE, NORTH MACEDONIA: TWO-TIME POINTS POPULATION-BASED CROSS-SECTIONAL STUDY(University Ss. Cyril and Methodius in Skopje, 2023); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, LEUKOTRIENE RECEPTOR ANTAGONISTS IN MANAGING SEVERE UNCONTROLLED ASTHMA(European Medical Group, 2017-08-03); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Association of 22 cytokine gene polymorphisms with tuberculosis in Macedonians(2009-07); ; Strezova, AnaTo examine the possible role of 22 cytokine gene polymorphisms in host susceptibility to or protection against tuberculosis (TB) in Macedonians. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Serum homocysteine levels and methylenetetrahydrofolatereductase genotypes in couples with idiopathic recurrent miscarriage(Balkan Clinical Laboratory Federation (BCLF), 2015-10); ; ; Aleksandar Senev - Some of the metrics are blocked by yourconsent settings
Item type:Publication, IL-33 in patients with severe uncontrolled allergic asthma(European Respiratory Society, 2017-09); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Distribution of Killer Cell Immunoglobulin-Like Receptor Genes in Albanians from Republic of Macedonia(ID Design 2012/Scienfitic Foundation SPIROSKI, 2015-02-19); ; ;