Jota, GJorgji
Preferred name
Jota, GJorgji
Official Name
Jota, GJorgji
Main Affiliation
Email
gjorgji.jota@medf.ukim.edu.mk
23 results
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Item type:Publication, Tumour Lymphocytic Infiltration, Its Structure and Influence in Colorectal Cancer Progression(Scientific Foundation Spiroski, 2018); ; ; ;Dragan Hadzi-ManchevThe role of the immune system in the control of tumour progression has been stressed, recently. Many studies indicate the fact that the immune system can prevent tumour progression in several types of human malignant neoplasms including colorectal cancer. According to some authors, a higher density of “tumour-associated lymphocytes” (TAL), in malignant neoplasms, correlate with prolonged survival of patients. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Tertiary Lymphoid Structures in Colorectal Cancers and Their Prognostic Value(ID Design 2012/DOOEL Skopje, 2018-10-25); ; ;Karadzov, Zoran; Hadzi-Manchev, DraganTumor-infiltrating lymphocytes (TIL) in tumour stroma are considered to be involved in the elimination of malignant cells and prevention of metastasis formation. TIL consist of T lymphocytes including cytotoxic lymphocytes that are a constituent part of the effector mechanism of anti-tumour immunity and B lymphocytes that can form tertiary lymphoid structures (TLS). TLS has been described in several solid tumours and colorectal carcinoma (CRC), and the influence on the local and systemic anti-cancer response. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Pancreas and duodenum herniation in a giant inguinal hernia sac in a patient with severe scoliosis: a rare case report(Oxford University Press (OUP), 2025-07) ;Gelevski, Radomir; ; ; Giant inguinal hernias (GIHs) are rare clinical entities, typically containing omentum or small bowel. Involvement of retroperitoneal organs, such as the pancreas and duodenum, is exceedingly uncommon due to their fixed anatomical positions. We report a unique case of a 52-year-old male with a longstanding right GIH and severe scoliosis, in whom preoperative imaging and surgical exploration revealed herniation of the pancreatic head and duodenum into the hernia sac. Contributing factors included altered retroperitoneal geometry from spinal curvature, reduced abdominal wall tone, and congenital right hip displacement with associated functional limitation. Incidental findings of multiple left hepatic duct calculi raised concerns for biliary stasis due to chronic duodenal displacement. This case highlights the importance of considering atypical hernia content in patients with longstanding hernias and complex musculoskeletal deformities, and underscores the role of comprehensive imaging and multidisciplinary assessment in surgical planning. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The effect of a small dose of ketamine on postoperative analgesia and cytokine changes after laparoscopic cholecystectomy(Macedonian Academy of Sciences and Arts, 2012); ; ; ;Nikolova Todorova, Z.In this study we assesed the effect of a small dose of ketamine on the production of TNFα, IL-1β and IL-6 and the postoperative pain in patients undergoing laparoscopic cholecystectomy. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Effect of Adding Dexamethasone as a Ropivacaine Adjuvant in Ultrasound-Guided Transversus Abdominis Plane Block for Inguinal Hernia Repair(Macedonian Academy of Sciences and Arts / Walter de Gruyter GmbH, 2015); ; ; ;Zdravkovska, MilkaBackground: The transverses abdominals plane block (TAP) is a regional anesthesia technique that provided analgesia to the parietal peritoneum, skin and muscles of the anterior abdominal wall. The aim of this randomized double-blind study was to evaluate postoperative analgesia on patients undergoing open inguinal hernia repair under general anesthesia (GA), (GA + TAP) block preformed with ropivacaine and (GA + TAP-D) block preformed with ropivacaine and 4 mg dexamethasone. Methods: 90 (ASA I-II) adult patients for unilateral open inguinal hernia repair were included in this study. In group I (n = 30) patents received only general anesthesia (GA). Patients in group II (n = 30) received GA and unilateral TAP block with 25 ml of 0.5% ropivacaine and the patients in group III (n = 30) received GA and unilateral TAP-D block with 25 ml of 0.5% ropivacaine + 4 mg Dexamethadsone. In this study we assessed the pain score - VAS at rest at 2, 4, 6, 12 and 24 hours after the operation and the total analgesic consumption of morphine over 24 hours. Results: There were statistically significant differences in the VAS scores between group I, group II and group III at all postoperative time points - 2(hr), 4(hr), 6(hr), 12(hr) and 24(hr). (p < 0.00001). The cumulative 24 hours morphine consumption after the operation was significantly lower in group III (5.53 1.21 mg) than in group II (6.16 2.41 mg) and group I (9.26 2.41 mg). This difference is statistically significant (p < 0.00001). Conclusion: Concerning the inguinal hernia repair we found better postoperative pain scores and 24 hours reduction of the morphine consumption in group III (GA and TAP-D block) compared with group I (GA) and group II (GA + TAP block). - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Ефект на кетамин во мултимодален режим на постоперативна континуирана епидурална аналгезија кај пациенти со колоректален карцином(Medical Faculty, Ss. Cyril and Methodius University in Skopje, 2011); ;Николова-Тодорова Зорка; ;Џамбазовска-Трајковска Вања - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Heterotopic pancreas in the hepatobiliary triangle(Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University, Skopje, Macedonia, 2020) ;Gelevski R; ; ; Bajdevska Dukovska D - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Laparoscopic cholecystectomy in situs inversus totalis: A case report(Centre for Evaluation in Education and Science (CEON/CEES), 2021) ;Gelevski, Radomir; ;Todorovich, Lazar; Situs inversus totalis represents a rare autosomal recessive morphological anomaly of the internal viscera, equally affecting both genders. The genetic defect occurs in the 2nd week of embryonic life, when a 270-degree clockwise rotation of the primitive digestive tube occurs. The incidence of calculosis of gallbladder in patients with situs inversus is the same as in the general population. A 61-year-old female patient with a history of four episodes of colicky, left hypochondrium and epigastric pain, without fever and jaundice, was admitted for elective laparoscopic cholecystectomy. CT of abdomen confirmed situs inversus totalis that was previously known to the patient. The patient was positioned in supine position and a mirror image configuration of the operating room was obtained, with surgeon and scrub nurse on the right side and assistant on the left side of the patient. Four trocars were introduced mirroring the standard position of the 5 mm trocars. During the dissection, second assistant was introduced for the laparoscope, due to the surgeon's limited motor skills in his left hand for delicate dissection, rendering him inapt to perform precise and safe dissection. The total operating time amounted to 110 minutes, which is three times longer than the standard operating time at our institution. The most critical point of the operation in constellation of situs inversus totalis is applying the clips, which requires precision and strength in the same moment. In the available literature, 40 open cholecystectomies before introduction of laparoscopy and 92 laparoscopic cholecystectomies were reported. To our knowledge, this is the first and the only reported laparoscopic cholecystectomy for situs inversus in North Macedonia. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, True left-sided gallbladder (T-LSG) as incidental finding on laparoscopic cholecystomy - case report(Macedonian Association of Anatomists, 2021) ;Radomir Gelevski; ; ; Left - sided gallbladder, located medial ly t o the falciform ligament, between segment III and IV of the liver, has complex embryological development explained by two different concepts: one founded upon f o etal migration of the gallbladder ; and the other founded upon complex f o etal evolution of intrahepatic anatomy. 57 - year - old male was admitted for elective cholecystectomy, and , after pneumoperitoneum was established , a true left - sided gallbladder was identified. The patient wa s positioned in normal position and ports were placed on typical sites. After diligent dissection, cystic artery and duct were clipped as close as possible to gallbladder and dissected. During standard dissection in laparoscopic cholecystectomy, special at tention was dedicated to obtaining posterior critical view of safety, providing adequate exposition of structures of Calot’s triangle. Posterior critical view of safety in left - sided gallbladder exposes cardinal structures of hepatic hilus. Although, duri ng laparoscopy , difficult anatomy is met and there is high probability of bile duct injury, laparoscopic cholecystectomy is the recommended procedure of choice for left - sided gallbladder. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Risk Factors for Early Postoperative Complications after Surgery for Crohn's Disease(Centre for Evaluation in Education and Science (CEON/CEES), 2014-09-01); ; ; ;Milev, IlijaGelevski, Radomir<jats:title>Summary</jats:title> <jats:p> The aim of this study was to show the influence of various risk factors on early postoperative complications following surgery for Crohn’s disease (CD). In this review, an online internet database was searched, and also systematic review of the literature was performed. Three different studies from different countries were analyzed and compared with the results obtained in our University Clinic of Digestive Surgery - Skopje. The first review shows the influence of positive resection margins in CD on septical complications occurrence in patients undergoing ileocolic resection for CD at the Tel Aviv Medical Centre - Israel. The second review shows the risk factors for complications after bowel surgery in Korean patients with CD using data from the Asan Medical Centre - Seul, Korea. The third review shows that the delay of surgery is associated with inferior postoperative outcome in patients treated for perforating Crohn’s ileitis, and the study was conducted using data from the medical records of patients treated at the Department of Surgery at the University of Regensburg, Germany. Finally, we analyzed the influence of the most common risk factors on early postoperative complications in patients that underwent surgery for Crohn’s disease in a five-year period at the University Clinic of Digestive Surgery in Skopje, Macedonia and compared them with the results in the aforementioned articles.</jats:p>
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