Cvetanovska ilievski, Biljana
Preferred name
Cvetanovska ilievski, Biljana
Official Name
Cvetanovska ilievski, Biljana
Translated Name
Цветановска Илиевски, Биљана
Alternative Name
Cvetanovska Ilievski B
Biljana Cvetanovska Ilievski
Biljana Cvetanovska
Биљана Цветановска Илиевски
Main Affiliation
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Item type:Publication, THE ROLE OF THE FAECAL SAMPLES CULTIVATION IN THE DIAGNOSTICS OF CLOSTRIDIOIDES DIFFICILE INFECTION(University Ss. Cyril and Methodius in Skopje, 2025-11-25); ; ; ; <jats:p>Introduction: Clostridioides difficile is one of the most important intra-hospital pathogens. A few years ago, a new diagnostic algorithm for Clostridioides difficile infection (CDI) was introduced by ESCMID, stating that cultivation of the bacteria is not necessary for the diagnosis of CDI. Aim: We aimed to explore the role of the cultivation of faecal samples in the diagnosis of CDI. Materials and Methods: In 4 years, we have cultivated 80 different strains of C. difficile from as many patients. Initially, 1380 faecal samples from CDI-suspected patients were planted on selective and non-selective blood agar media and were accordingly incubated in order to isolate the strains. Quick immuno-chromatographic tests were performed on each faecal sample for detection of GDH (glutamate dehydrogenase) and C. difficile toxins A and B as well as on each confirmed C. difficile isolate (from one colony-toxins detection only). Results: In 14 of the 80 faecal samples from which the isolates originated, toxins A and B have not been detected. In 8 of these 14 strains, toxins A and B were detected only from the culture. Only 6 strains were confirmed as non-toxigenic. Conclusions: Although there was no statistical significance, the detection rate of C. difficile toxins A and B was higher from the culture than from the faecal samples by up to 10%. Cultivation of the samples for C. difficile could reduce the rate of false negative findings for CDI.</jats:p> - Some of the metrics are blocked by yourconsent settings
Item type:Publication, RISING TREND OF USING LAPAROSCOPY IN THE TREATMENT OF COMPLICATED APPENDICITIS IN OUR INSTITUTION DURING JANUARY 2017-MAY 2019(Македонско лекарско друштво = Macedonian Medical Association, 2019); ; Abstract Introduction. Laparoscopic appendectomy was performed for the first time in the University Clinic for Surgery “St. Naum Ohridski” back in 2003 by the pediatric surgeons. At the moment it is still unrecognized by many senior surgeons as a reliable and safe alternative procedure for acute appendicitis. The end-point of this study is to present the rising trend of using laparoscopy in the treatment of complicated appendicitis. Methods. In the period between January 2017 and May 2019 a total number of 403 patients were operated on due to a preoperative diagnosis of acute appendicitis (270 with open and 133 with laparoscopic appendectomy) and were retrospectively analyzed. Results. Simple appendicitis was diagnosed intraoperatively in 248 patients and complicated appendicitis was diagnosed in 141 patients. The rising trend for overall use of laparoscopy for acute appendicitis was seen during the study period (20.9%, 32.2% and 63.3% in 2017, 2018 and 2019, respectively). In terms of complicated appendicitis, a drastic positive trend followed in favor of laparoscopy (8.9%, 24.6% and 36.7% in 2017, 2018 and 2019, respectively). The negative appendectomy rate with other intraoperative finding was 3.46% (14 cases). The conversion rate was 2.25%. Conclusion. We can finally conclude that the laparoscopic appendectomy is recognized as an effective and safe alternative in the treatment of complicated appendicitis in our institution.