Kostovski, Marko
Preferred name
Kostovski, Marko
Official Name
Kostovski, Marko
Main Affiliation
Email
marko.kostovski@medf.ukim.edu.mk
34 results
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Item type:Publication, The most common bacterial isolates from wound samples – a three-year study(INSTITUTE OF PUBLIC HEALTH OF REPUBLIC OF NORTH MACEDONIA, 2021); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Duplication of the SOX3 Gene in an Sry-negative 46, XX Male with Associated Congenital Anomalies of Kidneys and the Urinary Tract: Case Report and Review of the Literature(Macedonian Academy of Sciences and Arts, 2019); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Severe digital malformations in a rare variant of fibrodysplasia ossificans progressiva(Wiley, 2019-04-22); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Cranberry, a potential alternative treatment for urinary tract infections(Macedonian Association of Anatomists, 2023); ; ; ; Radomir JovchevskiVaccinium macrocarpon is perennial plant traditionally used as an herbal medicine in treatment and prevention of UTIs. Although the mechanisms of action are not jet fully understood it is presumed that they involve interferation with bacterial adhesion and changes in bacterial morphology mainly attributed to the plants proanthocyanidins. C ranberry extracts (CE) standardized for different concentrations of proanthocyanidinnes (PACs), CE in combination with antibiotics (norfloxacin and vancomy cin) and antibiotics alone (only antibiotics) were investigated for their effect on different strains of uropathogenic E.coli, S. saprophyticus and E. faecalis . As a source of CE we used commercial herbal supplements containing only Vaccinium macrocarpon extract (37.5 mg PACs) or CE in combination with D - manoza (25, 3 mg PACs). We used bacterial strains isolated from out patients with UTI s reffered for routine urine examination at the Institute of microbiology and parasitology. Sensitivity of the pathogen s to CE (as monoagent or combined in herbal mix) was evaluated with disc diffusion method. Our results showed stronger effect of CE on the growth of E.coli compared to G ram - positive strain s . S. saprophyticus strains were more susceptible to the extract/herbal mixes compared to the enterococci which predominantly presented as recalcitrant to the inhibitory activity of cranberry/herbal mixes. The sample size of this study was small to draw definite conclusions but our results illuminate avenues for future re search of the potential of cranberry as an alternative treatment in patients with UTIs. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Severe digital malformations in a rare variant of fibrodysplasia ossificans progressiva(Wiley-Blackwell, 2019); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Antimicrobial resistance in Gram-positive bacteria isolated from blood culture(Macedonian Association of Anatomists and Morphologists, 2024-10); ; ; ; Blood cultures are essential in diagnosing the existence of bacteria in the blood and they continue to be the gold standard for the diagnosis of septicemia. From Gram-positive bacteria, Staphylococcus aureus and Enterococcus spp. are the most common bacteria causing sepsis and septic shock. They are the leading causes of hospital-acquired infections globally. Aim of the paper was to identify Staphylococcus aureus and Enterococcus spp. from hemoculture and to determine their susceptibility to antibiotics. Blood samples from hospitalized patients admitted for routine laboratory testing at the Institute of Microbiology from January 2023 to December 2023 were included in the study. Blood cultures bottles were incubated in automated Bact/Alert system. Isolated colonies were identified using automated VITEK 2 Compact system. MSSA and MRSA were isolated in 48.2% and 51.8% respectively. All isolates 100% were resistant to penicillin. Intermediate sensitivity to levofloxacin 92%, 60% and ciprofloxacin 96%, 64% was observed in MSSA and MRSA strains. Resistance to gentamicin of 63% was seen in MSSA isolates. Non-VRE and VRE were isolated in 67% and 33% respectively. Non-VRE strains had higher resistance towards gentamicin 77%, streptomycin 66%. VRE strains were resistant to gentamicin 93%, ampicillin 85%. Our findings give analysis of Gram-positive bacteria isolated from hemoculture and their resistance pattern. The findings give clinicians an insight for the right treatment option. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, List of Recommended Names for bacteria of medical importance: report of the Ad Hoc Committee on Mitigating Changes in Prokaryotic Nomenclature(Microbiology Society, 2025-10); Margos, GabrieleThe Ad Hoc Committee on Mitigating Changes in Prokaryotic Nomenclature was recently established under the auspices of the International Committee on Systematics of Prokaryotes to address the impact of name changes of prokaryotic taxa in databases, scientific publications and other sources, particularly agencies responsible for establishing protocols and standards for infectious disease control. Here, we report on the activities of the committee and the actions taken to date. A first key task of the Committee was to emphasize to stakeholders that the vast majority of name changes are not mandatory under the International Code of Nomenclature of Prokaryotes (ICNP), and to provide guidance. The second key task was to compile a List of Recommended Names (LoRN) for bacteria of human or veterinary medical importance. This list has been incorporated into the List of Prokaryotic names with Standing in Nomenclature (LPSN) and is easily and freely available from LPSN. The principles for compiling and updating the list are described. Use of this list, rather than automatically treating the most recently proposed name of a taxon that has obtained standing under the ICNP as the name to be applied to the taxon, will greatly reduce the burden on practitioners who need to use prokaryotic names, e.g. in human and veterinary medical routines, and the risk associated with new, unfamiliar names. Other databases are encouraged to use LoRN. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, ANTIMICROBIAL RESISTANCE IN GRAM NEGATIVE BACILLI ISOLATED FROM BLOOD CULTURE(University Ss. Cyril and Methodius in Skopje, 2023); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Candidatus List No. 6(Microbiology Society, 2025-06); Göker, MarkusBased on the guidelines of Appendix 11 of the International Code of Nomenclature of Prokaryotes (ICNP) [1, 2], a list in the form of a codified record of Candidatus organisms should be published at appropriate intervals in the International Journal of Systematic and Evolutionary Microbiology (IJSEM). In order to comply at least partially with the guidelines of Appendix 11, the List Editors have previously presented Candidatus List No. 1, which contained an inventory of the names of Candidatus taxa compiled from the literature published up to the end of 2018 [3]. Candidatus List No. 2, with names proposed in 2019 [4], was published in 2021, and Candidatus Lists No. 3 and 4, with names proposed in 2020 and 2021, respectively, were published in 2022 [5, 6]. The rank of phylum has recently been included [7] in the rules of the ICNP [1]. The first Candidatus Phylum List was published in 2023 [8]. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Naming the genus Marivivens and its species: etymological considerations(Microbiology Society, 2025-04);