Antova, Emilija
Preferred name
Antova, Emilija
Official Name
Antova, Emilija
Translated Name
Антова Емилија
Alternative Name
Antova,E
Hristova Antova E
Hristova E
Hristova Emilija
Main Affiliation
Email
emilija.antova@medf.ukim.edu.mk
22 results
Now showing 1 - 10 of 22
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Item type:Publication, Role of Echocardiography in Diagnosis and Treatment of Patients with Infective Endocarditis(Македонско лекарско друштво = Macedonian Medical Association, 2014-08-01); ; <jats:title>Abstract</jats:title> <jats:p>Infective endocarditis is an endovascular microbial infection of cardiovascular structures, localized on valves, large intrathoracic vessels, ventricular and atrial endocardium and prosthetic materials. IE may present as an acute, subacute and chronic disease. The incidence of IE ranges from one country to another within 3-10 episodes/100.000 persons per years. The classification of IE according to the localization of the infection is: left-sided native valve IE, left-sided prosthetic valve IE (PVE), right-sided IE and device-related IE.</jats:p> <jats:p>Echocardiography plays a key role in each of the steps of assessment of IE: the diagnosis, risk stratification and follow-up of patients with infective endocarditis. The major echocardiographic criteria for IE are discovering vegetations, abscess, new valvular regurgitation and prosthesis dehiscence. According to the recent ESC recommendation for diagnosis and assessment of patients with IE, in all patients with clinical suspicion of IE, transthoracic echocardiography (TTE) is the first step of assessment. If we speak about patients with prosthetic endocarditis, then transoesophageal echocardiography (TEE) is recommended in case of poor quality of TTE and in majority of patients with positive TTE. If TTE examination is negative with low suspicion of IE, further follow-up has to be stopped. If TTE is negative but there is a high suspicion of IE, TEE has to be repeated in 7-10 days. Anatomical features on IE echocardiography have specific characteristics: vegetation, destructive valve lesion (perforation, prolapse of the valve) and abscess formation (more frequent in <jats:italic>Ao valve and in prosthetic valve</jats:italic>), which can be complicated with pseudoaneurysm and fistulization). Other cardiac imaging modalities (multislice computed tomogramphy (CT), magnetic resonance, 18F-fluorodesoxyglucose PET-CT, and single photon emission computed tomography (SPECT) /CT sometimes can be used in discovering complications in IE.</jats:p> <jats:p><jats:bold>Conclusion:</jats:bold> Echocardiography is useful in diagnosis of endocarditis, assessment of the severity of the disease, prediction of short-term and long-term prognosis, prediction of embolic risk, management of its complications, as well as deciding whether to operate or not and in choosing optimal time for surgery and follow-up.</jats:p> - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Single-Photon Emission Computed Tomography Myocardial Ischemia Detection in High-Risk Asymptomatic Patients: Correlation with Coronary Calcium Score and High-Sensitivity C-Reactive Protein(2019); ; ; Apostolopoulos, VassoThe association between myocardial ischemia in high-risk patients with coronary calcium score (CCS) and high-sensitivity C-reactive protein (hs-CRP) is not well established. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Effect of nephrology referral on the initiation of haemodyalisis and mortality in ESRD patients(Macedonian Academy of Sciences and Arts, 2007-12); ; ; Gelev, SLate nephrology referral of patients with chronic kidney disease (CKD) has been suggested as increasing mortality after the initiation of dialysis. The aim of this study was to assess the impact of nephrology referral on the initiation of haemodyalisis (HD) and mortality during HD treatment in end-stage renal disease (ESRD) patients who have died in our institution over a five-year period. We studied data from all 117 patients on HD treatment in our institution who died (after 90 days of HD treatment) in the period between 01.01. 2002 and 31.12. 2006. Early (ER) and late referral (LR) were defined by the time of follow-up by a nephrologist greater than or less than 6 months, respectively, before the initiation of haemodialysis. Out of a total of 117 patients, 37.6% (44 patients) started HD in the ER group and 62.4% (73 patients) in the LR group. At the start of HD, LR patients were older, had a higher proportion of temporary catheters and had a significantly lower levels of haemoglobin and diuresis. Creatinine clearance was less in the LR (7.67 +/- 3.86 ml/min/1.73 m2) vs. the ER group (8.70 +/- 3.62 ml/min/1.73 m2), but not significantly different. Cardiovascular disease (CVD), defined by a history of myocardial infarction, cerebral vascular disease, peripheral arteriopathy, and/or heart failure, was also significantly more common among LR patients compared to ER (56%; 27%, p = 0.002). During the haemodyalisis treatment, the LR group had significantly lower levels of haemoglobin and haematocrit. CVD accounted for about 64% of deaths observed in the LR group. According to echocardiography data, there were no significant differences in the left ventricular mass index (LVMI) between the LR and ER groups at the time of dialysis initiation, but during haemodialysis treatment the LR group had significantly greater LVMI than the ER group (232,96 +/- 92,48 g/m2 vs.184,09 +/- 51,74 g/m2; p = 0,031). The time until death in months during dialysis treatment was significantly different between the LR and ER group, (69.51 +/- 64.03 vs.113.27 +/- 89.03, p = 0.0025). LR patients experienced a greater degree of anaemia and a high prevalence of CVD at the time of dialysis initiation. Our data suggest that the anaemia, CV damage and progression of left ventricular hypertrophy (LVH) in the LR patients during haemodialysis treatment are associated with poor survival on haemodialysis. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Multi-System Complications after Intravenous Cocaine Abuse(Scientific Foundation SPIROSKI, 2017-04-15); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Nt-proBNP DISCRIMINATORY ROLE BETWEEN SYMPTOMATIC AND ASYMPTOMATIC PATIENTS WITH SEVERE VALVULAR AORTIC STENOSIS(Macedonian Academy of Sciences and Arts, 2018-08-13); ; ; Nikola Hadzy-PetrushevBackground: The aim was to evaluate the Nt-proBNP discriminatory role between symptomatic and asymptomatic patients with severe aortic stenosis. Methods: 187 patients with severe valvular aortic stenosis, with normal EF > 50%, were included, 61 asymptomatic and 126 symptomatic. We used clinical, laboratory (Nt-proBNP) and echocardiographic parameters. Endpoints of monitoring (occurrence of event) were: the onset of symptoms in asymptomatic patients and death in both groups. Results: The symptomatic group with severe AS had a significantly higher means of Nt-proBNP, in comparison with the asymptomatic group. Nt-proBNP was a significant predictor for the risk of event occurrence (HR 1.4). In the group of severe AS without CAD (n = 101), the subgroup with Nt-proBNP above the cut-off value, took significantly higher percentage of patients with chest pain, fatigue and syncope. In the group with Nt-proBNP above the cut-off value, we had a significantly higher percentage of patients with severe AS without CAD, compared to those with CAD (n = 142). Nt-proBNP was negatively correlated with AVA and LVEF, whether the positive correlation was expressed for: LVEDd, LVEDs, IVSd, AV_Vmax, AV_MaxGrad, LVM and LA. Patients with Nt-proBNP above the cut-off, had a significantly lower event free survival, compared to patients with Nt-proBNP below the cut-off (n = 187; n = 101). Conclusion: The Nt-proBNP cut-off> 460 pg/ml was confirmed as a useful tool in the determination of event free survival in patients with severe AS. Nt-proBNP not only had relevance in the assessment of the severity of the disease, but also was a significant predictor for the risk of event occurrence. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Hyperfibrinogenemia in Peripheral Arterial Disease: Coexistent and Independent Risk Factor (A Report of Two Cases and Review of Literature)(Macedonian Academy of Sciences and Arts / Walter de Gruyter GmbH, 2018-12-01); ; ; Bosevska, GolubinkaThese case reports aim to show that hyperfibrinogenemia is a risk factor for the progression and prognosis of peripheral arterial disease (PAD), in patients with and without diabetes mellitus type 2. We present a patient with PAD who has type 2 diabetes mellitus, who has previously been repeatedly treated for lower limb ischemia with multiple vascular surgeries performed. A few weeks before admission the patient developed critical lower limb ischemia, which was treated with an iliaco-popliteal and femorofemoral bypass. The patient had elevated serum fibrinogen values. In the current admission, renewed left limb ischemia was diagnosed, and surgically evaluated with a recommendation for amputation of the left limb as a surgical recommendation. Our second patient had a stable intermittent claudication, dyslipidemia and hyperfibrinogenemia. He was successfully treated for those risk factors. Regular monitoring of the patient showed improved claudication distance and quality of life Our case reports, supported by a literature review, demonstrate that hyperfibrinogenemia is a possible risk factor for progression and the prognosis of PAD. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Color Duplex Sonography Findings of the Carotid Arteries and Associated Risk Factors in Patients with Transient Ischemic Attack(Macedonian Medical Association = Македонско лекарско друштво, 2016-01-01); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Myocardial gated SPECT imaging in asymptomatic diabetic patients: clinical decision and optimal therapeutic approach(Medical Publishing, d.o.o., 2013-05-14); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Impact of Post-Transplant Dysglycemia on Renal Allogrfat Function in Kidney Transplant Recipients on Cyclosporine-Based Immunosuppression(Македонско лекарско друштво / Walter de Gruyter GmbH, 2017-06-01); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The Impact of Glyco-Metabolic Status in Patients Treated for Acute Coronary Syndrome(Macedonian Academy of Sciences and Arts/ Walter de Gruyter GmbH, 2018-07-01); ; ;
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