Sazdova, Irena
Preferred name
Sazdova, Irena
Official Name
Sazdova, Irena
Translated Name
Саздова Данова, Ирена
Alternative Name
Sazdova Danova, Irena
Sazdova Danova, I
Sazdova, I
Ирена Саздова Данова
Irena Sazdova Danova
Main Affiliation
Email
irenasazdova@medf.ukim.edu.mk
5 results
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Item type:Publication, 99mTc-MIBI SPECT/CT imaging contribution in the diagnosis of patients with hyperparathyroidism(Research Center for Nuclear Medicine (Tehran University of Medical Sciences), 2019-01); ; ; Introduction: Hyperparathyroidism is presented with increased parathyroid hormone (PTH) secretion due to hyperfunctioning of one or more of the four parathyroid glands. Primary hyperparathyroidism (p-HPT) can be due to parathyroid adenoma, hyperplasia or carcinoma of the parathyroid gland. Secondary hyperparathyroidism (s-HPT) is usually a response to hypocalcaemia and consecutive hyperplasia of the glands. Our aim was to compare the efficacy of 99mTc-methoxyisobutylisonitrile (MIBI) SPECT/CT in identification of the location of the lesion(s) in cases of HPT by comparing these results with the findings of ultrasound (US) and planar scintigraphy. Methods: Forty one consecutive patients (54±17 age, 12 males and 29 females) with primary or secondary hyperparathyroidism were included. All patients were examined by US and afterwards patients underwent conventional double-phase 99mTc-MIBI scintigraphy combined with neck SPECT/CT procedure. Planar images (early and delayed), US and SPECT/CT image sets were evaluated for adenoma localization at the neck and thorax. Regions of interest (ROIs), equal sized, were selected and compared, over the hyperfunctioning parathyroid tissue (accumulated impulses-counts value) and over the contralateral lobe of the thyroid gland (control counts value). Results:The ultrasonography detected 24 positive findings. The late phase of planar scan detected 26 positive findings. SPECT/CT presented with bigger detection rate than late planar phase or US (75.6%, 63.4%, 61.5%) and with higher sensitivity (100%, 83.8%, 77.4%), respectively. Conclusion: The SPECT/CT study seems reliable, sensitive and with added value in diagnosing hyperparathyroidism as a complementary method to planar scintigraphy. US as compatible method, should be performed prior the scintigraphy protocols. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, DETECTION AND DETERMINATION OF RADIOACTIVE SURFACE CONTAMINATION WITH THE USE OF GAMMA CAMERA(University Ss. Cyril and Methodius in Skopje, 2025); ; ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Radiation exposure dose of medical workers during radioguided sentinel lymph node biopsy(Tehran University of Medical Sciences, 2022-04); ; ; ; Introduction: Radiation monitoring of professionally exposed workers is obligatory in nuclear medicine departments. The purpose of our study was to evaluate the radiation exposure dose received by medical workers during radioguided sentinel lymph node biopsy in breast cancer and endometrial cancer patients. Methods: Radiation exposure dose of medical staff was prospectively recorded during 35 radioguided sentinel lymph node biopsy procedures in a 6-month period. All patients received 4 mCi [99mTc]Tc-SENTI-SCINT on the day of surgery. Thermoluminescent dosimeters in the shape of a bracelet, ring and badge were used for recordings and data was compared to dose limits imposed by the regulations. Results: Mean time interval between activity administration and surgery was 223.63 min and mean duration of surgery was 142.5 min. The recorded 6-month cumulative dose was 0.33 mSv for the senior surgeon, 0.25 mSv for the surgeon's first assistant, 0.24 mSv for the anesthesiologist and 0.54 for both nuclear medicine physician and resident. The approximately equivalent dose for the surgical staff in each procedure was 9.7 µSv, 7.3 µSv and 7.05 µSv respectively, which means that the senior surgeon could perform 106 and 2127 sentinel lymph node biopsy procedures per year in order to reach the annual dose limit for a public member and a radiation worker. Conclusion: Occupational radiation exposure dose of medical staff during radioguided sentinel lymph node biopsy is low and under annual dose limits, requiring no routinely personal dosimetry for surgical staff performing the procedure. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Radiation exposure dose of medical workers during radioguided sentinel lymph node biopsy(Tehran University of Medical Sciences, 2022-07); ; ; ; Introduction: Radiation monitoring of professionally exposed workers is obligatory in nuclear medicine departments. The purpose of our study was to evaluate the radiation exposure dose received by medical workers during radioguided sentinel lymph node biopsy in breast cancer and endometrial cancer patients. Methods: Radiation exposure dose of medical staff was prospectively recorded during 35 radioguided sentinel lymph node biopsy procedures in a 6-month period. All patients received 4 mCi [99mTc]Tc-SENTI-SCINT on the day of surgery. Thermoluminescent dosimeters in the shape of a bracelet, ring and badge were used for recordings and data was compared to dose limits imposed by the regulations. Results: Mean time interval between activity administration and surgery was 223.63 min and mean duration of surgery was 142.5 min. The recorded 6-month cumulative dose was 0.33 mSv for the senior surgeon, 0.25 mSv for the surgeon's first assistant, 0.24 mSv for the anesthesiologist and 0.54 for both nuclear medicine physician and resident. The approximately equivalent dose for the surgical staff in each procedure was 9.7 µSv, 7.3 µSv and 7.05 µSv respectively, which means that the senior surgeon could perform 106 and 2127 sentinel lymph node biopsy procedures per year in order to reach the annual dose limit for a public member and a radiation worker. Conclusion: Occupational radiation exposure dose of medical staff during radioguided sentinel lymph node biopsy is low and under annual dose limits, requiring no routinely personal dosimetry for surgical staff performing the procedure. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Radiation exposure dose of medical workers during radioguided sentinel lymph node biopsy(Teheran University of Medical Sciences, 2022-04); ; ; ; Introduction: Radiation monitoring of professionally exposed workers is obligatory in nuclear medicine departments. The purpose of our study was to evaluate the radiation exposure dose received by medical workers during radioguided sentinel lymph node biopsy in breast cancer and endometrial cancer patients. Methods: Radiation exposure dose of medical staff was prospectively recorded during 35 radioguided sentinel lymph node biopsy procedures in a 6-month period. All patients received 4 mCi [99mTc]Tc-SENTI-SCINT on the day of surgery. Thermoluminescent dosimeters in the shape of a bracelet, ring and badge were used for recordings and data was compared to dose limits imposed by the regulations. Results: Mean time interval between activity administration and surgery was 223.63 min and mean duration of surgery was 142.5 min. The recorded 6-month cumulative dose was 0.33 mSv for the senior surgeon, 0.25 mSv for the surgeon's first assistant, 0.24 mSv for the anesthesiologist and 0.54 for both nuclear medicine physician and resident. The approximately equivalent dose for the surgical staff in each procedure was 9.7 µSv, 7.3 µSv and 7.05 µSv respectively, which means that the senior surgeon could perform 106 and 2127 sentinel lymph node biopsy procedures per year in order to reach the annual dose limit for a public member and a radiation worker. Conclusion: Occupational radiation exposure dose of medical staff during radioguided sentinel lymph node biopsy is low and under annual dose limits, requiring no routinely personal dosimetry for surgical staff performing the procedure.