Milenkovikj, Tatjana
Preferred name
Milenkovikj, Tatjana
Official Name
Milenkovikj, Tatjana
Alternative Name
Татјана Миленковиќ
Milenkovikj Tatjana
Milenkovik Tatjana
Milenkovic Tatjana
Миленковиќ Татјана
Миленковиќ Т
T. Milenkovic
T Milenkovic
Milenkovic T
Milenkovic. T
Т Миленковиќ
Т. Миленковиќ
Milenkovic Tatjana
Tatjana Milenkovic
Main Affiliation
Email
tatjana.milenkovikj@medf.ukim.edu.mk
62 results
Now showing 1 - 10 of 62
- Some of the metrics are blocked by yourconsent settings
Item type:Publication, Case report on a switch from hypothyroidism to hyperthyroidism(The Endocrine Society, 2023-01-18); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Successful desensitization in patient with type 2 diabetes with an insulin allergy using insulin pump and glargine(Springer, 2014-12); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Direct Molecular Diagnosis of CYP21A2 Point Mutations in Macedonian and Serbian Patients with 21-Hydroxylase Deficiency(Society of Medical Biochemists of Serbia, 2015-01); ; Steroid 21-hydroxylase deficiency is present in 90-95% of all cases with congenital adrenal hyperplasia (CAH), an autosomal recessive disorder. It can present as the severe classical salt wasting (SW) or simple virilising (SV) form, or the milder, nonclassical form. Nine pseudogene-derived point mutations account for about 80% of all defects in the CYP21A2 gene coding the 21-hydroxylase enzyme. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Obstructive Sleep Apnea and Lipid Abnormalities(ID-Design/Scientific foundation SPIROSKI, 2017-03-15); ; ; There has been a great interest in the interaction between obstructive sleep apnea (OSA) and metabolic dysfunction, but there is no consistent data suggesting that OSA is a risk factor for dyslipidemia. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Prediabetes awareness among Southeastern European physicians(Wiley Online Library, 2017-08-29) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Severe hyponatremia as presenting symptom of small cell lung carcinoma(The Endocrine Society, 2023-01); ; A 62-year-old female patient was admitted to ICU in our clinic with symptomatic severe hyponatremia with complaints of fatigue, vertigo, paresthesia of upper extremities and three episodes of loss of consciousness in the past month. She had been hospitalized two weeks before in neurology clinic because of the same symptoms. CT of the brain, EEG, ophthalmology examinations were negative. She did not complain of hemoptysis, cough, weight loss, fever, chest pain or dyspnea. Nephrologist was consulted and renal origin of the hyponatremia was excluded, before admission. Initial laboratory tests were glucose:5,47 umol/L,sodium:109 mEq/L,potassium;4.5 mEq/L,urea 3,9 umol/l;creatinine:52,7 mol/l,calcium:1,22umol/L,TSH 5;Cortisol 819nmol/L;ACTH:16,34 pg/ml. Her medical history included hypertension, primary hypothyroidism and history of smoking. Upon laboratory findings of low serum osmolality, high urine osmolality, high urine sodium levels and clinical euvolemia, and in the absence of renal, pituitary disfunction, adrenal insufficiency, inappropriate ADH syndrome was diagnosed and initially was treated with 3% NaCl. Since this treatment had no effect, it was started with fluid restriction, per os sodium intake was increased and therapy with loop diuretic was initiated, which resulted in correction of the hyponatremia. For the etiology consideration of inappropriate ADH syndrome CT of the thorax was performed, which revealed a neo infiltrative process with atelectasis in the poster basal segment of the left lobe. Histopathological sampling from the biopsy of the mass revealed small cell carcinoma of the lung. Metastasis were not detected. Since basal morning cortisol level was above upper range, with inappropriate measurements of ACTH constantly above 15 pg/ml, additional tests for ectopic Cushing syndrome were done. Overnight 1mg dexamethasone suppression test showed absent suppression of the morning cortisol values of 656nmol/L and ACTH of 22,14 pg/ml and absent circadian rhythm of cortisol secretion, with high measurements of midnight serum cortisol of 652 nmol/L. Diagnosis of ectopic Cushing syndrome and SIADH as part of paraneoplastic syndrome in small cell lung carcinoma was made. It is to be noted that patient had no significant symptoms or signs of hypercortisolemia.</jats:p> <jats:p>We report here a case of small cell carcinoma of the lung whose first presentation was with symptomatic hyponatremia as a result of inappropriate ADH syndrome. The most common neoplasms associated with hyponatremia are various forms of lung cancer. Because of the aggressive nature of the disease, the most common manifestation of small cell carcinoma of the lung is a metastatic one. Therefore, identifying the disease in earlier stages is very important. Unfortunately, these patients have low rates of survival and face a very poor prognosis even with treatment. The presence and early identification of paraneoplastic syndromes can be beneficial in this context. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The beneficial effect of L-thyroxine on lipid parameters in mild form of subclinical hypothyroidism(Bioscientifica, 2016-05-13); ; ; Introduction: Overt hypothyroidism and severe subclinical hypothyroidism (ScH) are associated with dyslipidaemia, and its condition is reversible after thyroid replacement therapy. We investigated the effect of levothyroxine therapy on lipid parameters in patients with mild form of subclinical hypothyroidism (ScH). Material and methods: Fifty-seven patients with newly diagnosed ScH with TSH levels below 10 mU/l and 30 age and sex-matched healthy subjects were included in the study. Lipid parameters were evaluated at the first visit in both groups, and after 6 months euthyroid stage in patients with ScH. Results: Average value of TSH in patients with ScH was 8.1 mU/l. At the baseline, ScH patients has a significantly higher total cholesterol and LDL-C levels, and lower HDL-C, than the control group (5.6±0.9 vs. 4.8±1.1, 3.4±1.0 vs. 2.9±0.8, and 1.5±0.5 vs. 1.7±0.9, mmol/L, P<0.05, respectively). Thyroid substitution therapy in ScH group, significantly decreased total cholesterol and LDL-C, and increased HDL-C (5.6±0.9 vs. 5.3±1.1, 3.4±1.0 vs. 3.2±1.1, 1.5±0.5 vs. 1.6±0.5, mmol/L, P<0.05 respectively). Also, TSH positively correlated with total cholesterol (r=0.147, P<0.05). Conclusion: Mild form of ScH is associated with hipercholesterolemia, which is reversible after levothyroxine treatment. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Diabetes Care in Republic of Macedonia: Challenges and Opportunities(Ubiquity Press, 2015); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Association Between Hormone Replacement Therapy and Glycemic Control in Postmenopausal Women with Type 2 Diabetes(Македонско лекарско друштво = Macedonian medical association, 2015-01); ; ;