Popovski, Vladimir

Preferred name
Popovski, Vladimir
Official Name
Popovski, Vladimir
Main Affiliation
Email
vladimir.popovski@gmail.com

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    Item type:Publication,
    Evaluation of salivary flow rate and salivary lactoferrin after radiotherapy of head and neck malignant neoplasms
    (Centre for Evaluation in Education and Science (CEON/CEES), 2023)
    Rogoleva Gjurovski, Sonja
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    Kostadinova, Lenche
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    The most common postradiation complication in patients with head and neck neoplasms resulting from decreased salivary flow rate is xerostomia which affects the quality of life of patients in a negative way. On account of that, the application of volumetric modulated radiation therapy (VMAT) is found to be more precise in dose application, thus the surrounding healthy tissues can be spared from the negative influence of radiation. The aim of this study was to evaluate the salivary flow rate and salivary lactoferrin levels in patients with head and neck malign neoplasms following radiation therapy. Material and Methods: The research sample consisted of 24 patients treated with different radiation techniques, in which the salivary flow rate was measured for one minute. Additionally, the concentration of lactoferrin was quantitatively evaluated using biochemical analyses. Results: Higher average values were obtained in patients treated with a lower dose of radiation with up to 60 Gy, especially in those treated with a volumetric modulated radiotherapy technique. Therefore, from the results of linear correlation between the evaluated variables of lactoferrin and salivary flow volume in ml/min, it can be concluded that the correlation between these two variables is statistically significant whereby the correlation is negative with the coefficient of correlation r (24) = -0.903; (p < 0.01). Conclusion: The salivary flow rate is higher in patients treated with volumetric modulated radiotherapy, whereby the lower the dose of radiation, the higher the values of excreted saliva per minute. Therefore it can also be concluded that the higher values of lactoferrin are considered to have anti-inflammatory characteristics and are indicators of inflammation, which can be used for prevention of the salivary glands from negative effects of the radiation therapy.
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    A robotic system powered by solar energy
    (Faculty of Computer Science and Engineering, Ss. Cyril and Methodius University in Skopje, Macedonia, 2013)
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    This paper describes the process of constructing a robotic system from scratch, using Lego bricks as constructing blocks and solar panels as energy source. The product is a robotic system (car) on 4 wheels powered by 32 small 0,08W solar panels. The paper describes the possibilities of using renewable energy sources, such as the solar energy, as driving energy for robots. Furthermore, this paper gives some ideas on how can this model be upgraded with more functionalities.
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    Anatomy and clinical importance of the triangle of Koch.
    (Macedonian Association of Anatomists and Morphologists, 2012)
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    The triangle of Koch occupies the atrial component of the muscular AV septum. The tissue of AV node and the “slow” and “fast” pathway of the AVNRT are incorporated in the triangle, which makes this area clinicaly important. The aim of this study was to present the morphology and clinical importance of the triangle of Koch. The study consists of two parts: basic and clinical. In the basic part, 100 human hearts fixed in formaldehyde were examined using common anatomical and histological methods. The numerical features of the triangle of Koch were measured in two different ways. In the clinical part of the study, the analysis was made on 100 patients who were tested and treated in the Electrophysiological laboratory of the Institute for Heart Diseases in Skopje. Using the data of patients weight and height, the numerical features of the triangle were calculated. The results obtained were statistically analysed. The first type of measuring, in the basic part of the study, gave the following mean values of the length of the sides of the triangle of Koch: side a (a1) 26.1 ± 3.1 mm, side b (b1) 20.8 ± 3.6 mm and side c (c1) 24.5 ± 2.5 mm. The mean value of the area of the triangle (P1) was 256.2 ± 67.6 mm2. According to the second type of measuring the following numerical features of the triangle were obtained: side a (a2) 20.8 ± 2.5 mm, side b (b2) 13.9 ± 2.8 mm and side c (c2) 19.8 ± 2.4 mm. The mean value of the area of the triangle (P2) was 139.47 ± 37.28 mm2. In the clinical part of the study, mean value of the length of the side a (a3) was 28.5 ± 2.7 mm, side b (b3) 12.9 ± 1.2 mm and side c (c3) 21.1 ± 2.7 mm. The mean value of the area of the triangle (P3) was 116.6 ± 12.3 mm2. Knowledge of the variations of numerical features of the triangle of Koch is fundamental for successful catheter placement in electrophysiological studies and radiofrequent catheter ablations.