Pushevski, Vladimir
Preferred name
Pushevski, Vladimir
Official Name
Pushevski, Vladimir
Main Affiliation
25 results
Now showing 1 - 10 of 25
- Some of the metrics are blocked by yourconsent settings
Item type:Publication, USE OF EVODIAL DIALIZERS FOR HEMODIALYSIS IN PATIENTS WITH HIGH RISK FOR BLEEDING - SINGLE CENTRE EXPERIENCE(Macedonian Association of Anatomists, 2023); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, LOWER SERUM POTASSIUM LEVEL IS ASSOCIATED WITH MORTALITY AS CONFOUNDING EFFECT OF MALNUTRITION IN DIALYSIS PATIENTS(Macedonian Association of Anatomists and Physiologists, 2019); ; ; Introduction: Obtaining normal serum potassium level is an important goal in maintenance hemodialysis patients. Hyperkalemia is known to be associated with mortality. In this study we aimed to assess the relationship between pre-dialysis potassium level, nutritional status and survival in dialysis patients. Materials and methods: This study used annual cohorts of hemodialysis patients with 36 months of follow-up. To determine the impact of potassium level on mortality, patients were followed from the first potassium measurement until death or a censoring event; hypokalemia was defined by potassium levels below median level - 5.5 mmol/l and albumin level below 35g/l was considered as an index for undernourished. Time-dependent Cox proportional hazards modeling was used to estimate the association between potassium level and mortality. Results: A total of 199 patients were included in the study. Mean age was approximately 56 years, about 59% were men and 23% had end-stage renal disease caused by diabetes. Albumin below 35 g/l was observed in 26 (13%) patients. In the follow-up period 53 (26%) patients died, consisting of 31 (31%) of the 101 hypokalemic and 22 (22%) of 98 hyperkalemic patients. The Kaplan-Meier survival rate was significantly better in the hyperkalemic population (34.300.71 vs. 31.061.16, p=0.051). Hypokalemia, when defined as serum potassium 5.5 mmol/l, was associated with all-cause mortality (hazards ratio (HR) 1.857, 95% CI 0.986-3.496, p = 0.051). The significance was lost in the model after adjustment for albumin level. Only albumin level determined mortality (p=0.03). Conclusion: Lower potassium level was associated with all-cause mortality, but only as a confounding effect of malnutrition in dialysis patients - Some of the metrics are blocked by yourconsent settings
Item type:Publication, P1102EVALUATION THE EFFICACY OF MEDIUM CUT- OFF MEMBRANE DIALYZERS AND COMPARISON WITH HIGH FLUX DIALYZERS IN CONVENTIONAL HEMODIALYSIS(Oxford University Press (OUP), 2020-06-01); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Hypomagnesemia and cause-specific mortality in hemodialysis patients: 5-year follow-up analysis(SAGE Publications, 2017-10-13); ; ; The aim of this prospective study was to evaluate the association between serum magnesium (Mg) and mortality, in particular the cause-specific mortality of Mg and other risk factors in hemodialysis (HD) patients. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Challenging Case of Multisystem Inflammatory Syndrome in a 19- Year Old Female: A Case Report(Macedonian Society of Nephrology, Dialysis, Transplantation and Artifical Organs, Department of Nephrology, 2022); ; Introduction. In comparison to older adults, SARSCoV-2, leads to a mild illness in children and young adults typically manifested with fever, cough and gastrointestinal symptoms. However, the multisystem inflammatory syndrome in children and young adults (MISC) emerged during the coronavirus disease in 2019 pandemic. Case report. We report a challenging case of a 19- year old female patient with signs and symptoms of multisystem inflammatory syndrome and SARS-CoV2 infection, most probably as a post infectious disease with onset between 2 to 4 weeks after the infection. Its clinical symptoms may have overlaped with classical Kawasaki disease (systemic vasculitis) or Kawasakilike syndrome (atypical) with fever, gastrointestinal symptoms, rash, conjunctival injection, hypotension, sore throat, mucosal changes with a relative lack of severe respiratory disease, myocarditis, hypoalbuminemia and elevated inflammatory markers. And indeed, the clinical presentation of COVID-19 in young adults resembles Kawasaki disease with gastrointestinal manifestations to severe inflammation with myocarditis. Conclusion. Timely diagnosis and proper treatment of the multisystem inflammatory syndrome and SARSCoV-2 infection are real challenge requiring multidisciplinary approach and tertiary resources. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Permanent Vascular Access for Hemodialysis in Elderly Patients - Single Center Experience(2019); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, FAMILY SUPPORT IS CRUCIAL FOR DIALYSIS PATIENTS COMPLIANCE TO TREATMENT AND QUALITY OF LIFE(Macedonian Association of Anatomists, 2020); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Association Between the Polymorphism of Angiotensin-Converting Enzyme Gene and Interleukin-1 Beta Gene and the Response to Erythropoietin Therapy in Dialysis Patients with Anemia(Walter de Gruyter GmbH, 2023-12); ; ; The polymorphism of the angiotensin-converting enzyme (ACE) gene and interleukin-1 beta (IL-1b) gene could be associated with resistance in the treatment of anemia in dialysis patients with recombinant human erythropoietin (rHuEPO). The aim of the study was to evaluate the association between the polymorphism of the ACE and IL-1b genes and the response to rHuEPO therapy in dialysis patients with anemia. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, P1505COMORBIDITY AND AGE OF DIALYSIS PATIENTS OUTPERFORMS FRAILTY BURDEN AS A PREDICTOR FOR MORTALITY(Oxford University Press (OUP), 2020-06-01); ; <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background and Aims</jats:title> <jats:p>The life expectancy in dialysis patients depends on patients’ age and comorbidities. Frailty in elderly patients is a state of impaired homeostasis with loss of physiologic reserve and a consequent impaired responses to dialysis burden. In this study we assessed the impact of age, comorbidities and frailty on dialysis patients’ survival.</jats:p> </jats:sec> <jats:sec> <jats:title>Method</jats:title> <jats:p>The study enrolled 162 prevalent patients on chronic hemodialysis with mean dialysis vintage of 100 months, 55% were women and 21 % had diabetes. Patients were divided into three groups by the Khan Comorbidity index score, highest score was considered worse. Frailty was assessed by presence of 3 or more symptoms (unintentional weight loss, feeling exhausted, weak grip strength, slow walking speed and low physical activity) and expressed as absolute number. Estimates of five years life expectancy were assessed by Kaplan Meier survival log-rank test and Cox regression hazard model.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>There were 26 (16%) with lowest score, 85 (52%) with medium score and worst highest score in 51 (31%). During the 5 years of follow up 69(43%) patients died of all-cause mortality. There were no deaths in the group with lowest score and mortality rates in the intermediate and worse score group increased by double (0; 30%; 69%, respectively). Significantly higher mean life expectancy was found in lower Khan Score groups: 60mo; 48.40 ± 18.51; 32.44 ± 22.06, log-rank: p < 0.012. Patients that scored worse had four folds higher risk for death HR 4.2 (95% CI: 2.72 – 6.36), p=0.0001. In the multivariate model Khan Score was a more powerful predictor of mortality than frailty in elderly, with HR 3.2 (95% CI: 2.88 – 5.41), p=0.0001.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusion</jats:title> <jats:p>Comorbidities and age outperforms frailty burden as a predictor of mortality in dialysis patients.</jats:p> </jats:sec> - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Excess Mortality in a Nephrology Clinic during First Months of Coronavirus Disease-19 Pandemic: A Pragmatic Approach(Scientific foundation Spiroski, 2020-12-20); ; ;
- «
- 1 (current)
- 2
- 3
- »