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    CORRELATIONS BETWEEN RED BLOOD CELLS’ VARIABLES, CARDIO-PHYSIOLOGICAL AND ANTHROPOLOGICAL VARIABLES IN YOUNG ATHLETES
    (Macedonian Academy of Sciences and Arts / Sciendo, 2020-06)
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    Jadranka Plavsic
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    Aim: The aim of this study was to determine and analyse the relations between anthropometric parameters,red blood cells’ (RBC) variables and cardio-physiological parameters in healthy and physically active children and adolescents. Material and Methods: In this study 625 subjects, (410 males and 215 females; age span 8 to 18 years) underwent body composition analysis (Matiegka method), blood analysis and ergometry testing (Bruce protocol). Results: In both groups, body height and weight were positively correlated with RBC variables. In female group almost all correlations between RBC variables and body components were insignificant. In boys all absolute body mass components showed positive correlations with RBC variables with notice that body fat mass had lowest correlation coefficient. Body fat percent (BF %) did not show any correlation with RBC variables in both gender groups. In boys BF % had moderate negative correlation with aerobic performance: exercise time (ET) and VO2max (rs = -0.41 and rs = -0.39). Lean body components showed weak positive correlations with ET and VO2max. RBC count did not show significant correlation with any cardio-physiological parameter in both groups. Haematocrit and haemoglobin showed weak positive correlations with VO2 max and general endurance (exercise time). In girls all correlations between cardio-physiological and RBC variables were insignificant. The relationship between all body components and all cardio-physiological variables in girls were statistically insignificant. Conclusions: Our findings revealed that there are some expected positive correlations between lean body mass components, aerobic performance and RBC variables in boys, while in girls such relations were not noticed.
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    Bioelectrical Impedance Technology in Sports Anthropometry: Segmental Analysis in Karate Athletes
    (Springer, 2018-09)
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    Dusana Cierna
    The modern equipment for evaluation of body composition use computerized technology to determine or estimate body components. Having a moderate amount of each component is important for healthy life. Quantification of fat has been prime focus of attention, but many coaches, sport scientists and sport physicians working with elite athletes recognize that knowledge of the amount and distribution of lean tissue, such as bone and muscle, can be just as important in determining sports performance. Bioelectrical impedance analysis (BIA) estimates the amount of total body water (TBW), fat free mass (FFM) and fat mass (FM) measuring the resistance of the body as conductor to a very small alternating electrical current. The investigated group was composed of twenty (20) elite level male karate athletes with the following characteristics (mean  SD): age =22.5 3.6 years, age span (18 to 27 years); height = 179.95 2.3 cm; body mass =77.5  9.8 kg. Body composition was diagnosed with the InBody 720, multifrequency (1-1000 kHz) bioelectrical impedance analyzer (BIA). Karate athletes are obliged to maintain their body weight within certain range if they want to stay in optimal weight category. Our results showed that Macedonian karatees have symmetrical and balanced distribution between left and right side of the body. The strongest advantage of BIA methodology and InBody devices, compared to other field methods in sports anthropometry, is the segmental lean mass analysis. Monitoring the segmental analysis could help in following the quality of nutritional and training regime or rehabilitation procedure in athletes.
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    BIOELECTRICAL IMPEDANCE ANALYSIS IN KARATE ATHLETES: BIA PARAMETERS OBTAINED WITH INBODY720 REGARDING THE AGE
    (Faculty of Physical Education, Sport and Health in Skopje, 2016)
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    The basic purpose of this paper is to make recognizable analysis of body composition with bioelectrical impedance analyzer, (especially with InBody 720) to the sports scientific public. To fulfill this assignment we would like to present numerous parameters of body composition obtained with InBody 720, in subjects younger than 18 years and older than 18 years, because of fact that this BIA device gives different final result sheets regarding the age limit of 18 years. We investigated 21 karate athletes, members of karate national team of Republic Macedonia, age span from 15 to 22 years. They were divided in two age different groups, up to 18 (U18) and over 18 years old (18+). The final result sheets for person younger than 18 years consists considerably less parameters than for subjects older than 18 years. Comparison of parameters common for both groups showed that U18 karate athletes had significantly lower mean values for following parameters: height (176.8  4.26cm vs. 179.8  5.35cm), body weight (69.05  7.4 kg vs. 77.43  8.71 kg), skeletal muscle mass (35.38  4.43 kg vs. 38.34  2.97 kg) and body mass index, BMI (21.8  1.31 kg/m2 vs. 23.97  2.26 kg/m2) than 18+ karate athletes. Younger athletes also had significantly lower parameters of obesity diagnose: body fat mass (6.73  1.98 kg vs 10.31  5.02 kg) and body fat percent (9.8  2.65% vs. 12.91  5.14%). The data from this paper could allow the health professionals, sport scientists, sport expert and athletes to get useful information about plenty of parameters of body mass analysis obtained with bioelectrical impedance analyzer.
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    Body Composition and respiratory parameters in different age groups of football players
    (Faculty of Physical Education, Sport and Health, Skopje, Republic of Macedonia, 2022)
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    Ejupi A
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    Abstract Pulmonary function tests (PFTs) are commonly used for evaluating respiratory status in healthy subjects and for patients with pulmonary disease. They have also become a part of routine health examinations in respiratory, occupational, and sports medicine, and in public-health screening. The results of PFTs are interpreted in relation to normal range reference values, as recommended by the guidelines of the American Thoracic Society (ATS) and the European Community for Coal and Steel (ECCS). Spirometry is a gold standard of pulmonary function tests that measures the capacity of inhales and exhales volumes, more often as a function of time. It is often used in pulmonary function procedures, having become indispensable for the prevention, diagnosis, and evaluation of various respiratory impairments. A number of 61 football players were divided into 2 groups according to age: I group - below 18 years old (13.85 ± 3.26) and II group - above 18 years old (23.82 ± 3.32). This study was performed at the Institute of Medical, Experimental and Applied Physiology and Anthropology, Medical Faculty in Skopje. The spirometry method was performed with the Spirobank II spirometer (Rome, Italy), for the following parameters: forced vital capacity (FVC) in L, forced expiratory volume in the first second (FEV1) in L, and the ratio FEV1/FVC ratio (%). Body composition analyzer InBody 720, Great Britain, was used to determine body weight (kg), body height (cm), body mass index - BMI (kg/m2 ), skeletal muscle mass - SMM (kg) and the amount of proteins (kg) and minerals (kg). There was a significant difference in 2 examined groups of football players regarding all body composition parameters (p<0.001). No statistically significant difference was found for FVC, FEV1, and for the FEV1/FVC ratio. There was a difference in body composition parameters between the two age groups, without any influence on respiratory parameters. All these results may contribute to proper selection of training procedures, appropriate diet, and personalized performance. Key words: spirometry; pulmonary function; body composition.
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    BODY COMPOSITION RELATED TO BODY MASS INDEX AMONG YOUNG ELITE FOOTBALL PLAYERS
    (Medical faculty, Ss Cyril and Methodius University in Skopje, 2017)
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    Abstract Introduction. Body composition is extremely important for athletes’ performance, thus assessment tools may be used to clarify their sports condition. The aim of the study was to investigate body composition measurements and maximal oxygen consumption related to body mass index (BMI) in young elite football players. Material and methods. A total of 29 young football players were divided into 3 groups related to the value of BMI: I group (n=8); II group (n=13); and III group (n=8). The subjects were submitted to the sub-maximal pulse approach on treadmill method (SchillerAg, MTM-1500 Bear, Switzerland) to measure VO 2max (ml/kg/min). A body composition analyzer (InBody720, Biospace Co, Seoul, Korea) was used to determine the body fat - BF (%), skeletal muscle - SM (%) and total body water – TW(L) including intracellular body water – ICW(L) and extracellular body water – ECW(L). For the statistical analysis, a t-test was performed upon which the significance for p<0.05 was considered. Results. The football players showed the highest VO 2 max value in the II group (p<0.05). BF showed increased value in the III group (p<0.02). SM did not show any significant difference between the groups. Body water composition showed no statistical significance. Conclusion. Due to our results, we may conclude that certain parameters may determine the condition of young athletes in order to select appropriate training procedures, proper diet, and personalized performance. Key words: football; body mass index; body composition.
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    ESTRADIOL: MECHANISM OF CARDIORENAL PROTECTION
    (Faculty of Physical Education, Sport and Health in Skopje, 2017)
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    Premenopausal women have a decreased incidence of cardiovascular disease and a decreased rate of progression of renal disease. With the onset of menopause, however, decreased synthesis of 17β-estradiol (estradiol) is accompanied by an increased incidence of cardiovascular disorders and accelerated progression of renal diseases. The glomerulus and the vascular wall are not static, and components of these structures dynamically increase, decrease, or reorganize in response to physiological and pathological stimuli. Although multiple cellular and biochemical processes are involved in glomerular and vascular remodelling, glomerular mesangial cells (GMCs) in the kidney and smooth muscle cells (VSMC) and endothelial cells in the vasculature are the final common pathway for dynamic changes in glomerular and vascular wall structure. Estradiol may induce protective effects on the renal and cardiovascular system by altering VSMC, GMC, or endothelial cell biology so as to prevent glomerular and vascular remodelling. The purpose of this review is to provide an overview of the participating mechanisms in this regard, as well as the mechanism of estradiol signalling in cardiomyocytes, with an emphasis on mechanisms that might be important in cardioprotection.
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    The resting metabolic values related to different sport disciplines
    (Faculty of Physical Education, Sport and Health, Skopje, Republic of Macedonia, 2022)
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    Abstract Athletes compared to physically inactive people have a higher percentage of muscle mass which is a result of their active lifestyle. Higher percentage of muscle mass contributes to higher value of resting metabolic rate (RMR) in athletes. The aim of this study is to compare the values of resting metabolic rate in different sports disciplines which will give us a general knowledge of the energy expenditure in different sports. A number of 79 male athletes from 4 different sports (handball, football, cycling and functional fitness) were included in this study. Bioelectrical analisator In Body 720, Great Britain was used for body composition analysis and indirect calorimeter Fit Mate, COSMED, (Italy) for resting metabolic rate. All participants completed questionnaires for their medical history and physical activity. The results showed that handball players have significantly higher values of height, weight and skeletal muscle mass compared to the other sports (p<0,05), while percentage of body fat was lowest among football players. Handball players have higher values for RMR compared to the other sports, but have statistically different values only compared to cyclists. Cyclists have significantly lower values for RMR compared to the other sports (p<0,05). Because RMR has a major impact on total daily energy expenditure (TDEE) we come to the conclusion that handball players have higher TDEE and they need a balanced nutritional regimen that will provide all required nutrients, preferably with a higher caloric rate. Key words: athletes; resting metabolic rate; energy expenditure
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    APPLICATION OF BIOELECTRICAL IMPEDANCE ANALYSIS OF BODY MASS IN ATHLETES
    (College of Sport and Health, Belgrade, 2017-05)
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    The primarily role of body mass analysis in sport anthropometry is to determine body mass components, especially muscle component and body fat. The bioelectric impedance analyzes (BIA) employs the principle that the tissues consist of abundance of water and electrolytes, such as muscles, offer less resistance and conduct the current easier than tissue poor with water, such as adipose tissue. The InBody 720 apparatus utilizes the latest technology of measuring body composition using the method of Direct Segmental Multifrequency Bioelectrical Impedance Analysis. InBody’s use four compartments body mass model: the total body water consists of intracellular (ICW) and extracellular water (ECW); the protein compartment, fat free mass (FFM); the mineral compartment and the body fat mass. The aim of this paper is to show which parameters could be obtained by BIA methodology employing the InBody 720 and to make this methodology familiar and recognizable to health and sport practitioners.
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    LEVELS OF ANXIETY AND DEPRESSION IN ELITE KARATE ATHLETES
    (Faculty of Physical Education, Sport and Health in Skopje, Republic of Macedonia, 2018)
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    The aim of the study was to assess the levels of anxiety and depression, in elite karate athletes on the beginning of the summer preparatory period. The investigation was carried out as part of regular periodical systematic physical check-up of athletes. Twenty nine elite male karate athletes (most of them members of the Macedonian national karate team) aged 15 to 29 years, were asked to fulfil the Beck Anxiety Inventory (BAI) and the Beck Depression Inventory (BDI). The BAI questionnaire consists of 21 questions related to various aspects of anxiety. The intensity of perceived anxiety for every question in BAI is scored from 0 to 3, with 0 representing the least serious and 3 the most serious symptoms. The sum of all items is calculated at the end. BAI scores from 0-7 were ranked as a normal anxiety level; 8-25 as moderate; and 26-63 as high anxiety. The degree of depressive symptoms was measured by the 21-item-revised form of Beck Depression Inventory. The BDI statements for each question are ranked from 0 to 3, with 0 representing the least serious and 3 the most serious symptoms. Scores of BDI ≤ 10 indicate absence of depressive symptoms, BDI scores from 11-20 indicate mild depressive symptoms, while BDI scores from 21-30 indicate moderate depressive symptoms. BDI scores higher than 30 indicate clinically manifest depressive episode. Mean value of the acquired BAI scores in elite karate athletes was 4,1 ± 3,8. One seventh of all athletes showed moderate levels of anxiety. Mean value of acquired BDI scores was 6,1 ± 5,5. Four athletes showed mild depressive symptom, while one athlete showed moderate depressive symptoms. There was a positive correlation between the degree of depressive symptoms and the age of the athletes (r=0,575).
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    ENERGY REGULATION BY DIFFERENT MOLECULES
    (Faculty of Physical Education, Sport and Health, Skopje, Republic of Macedonia, 2022)
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    Abstract Energy homeostasis is regulated by several physiological systems such as endocrine, gastrointestinal, and nervous system, that contribute to maintaining the balance between energy expenditure and energy intake. Food intake as well as food utilization are essential components in the maintenance of energy balance. Exercise is a state that interferes with energy regulation, thus it has a good impact on healthy lifestyle and long lifespan. The aim of the study was to discover the possible role of some energy regulation molecules and their influence during exercise. A number of 37 scientific studies from PubMed, ScienceDirect, MEDLINE, and Scopus databases were examined from the period of the last 20 years, combining the physiological mechanisms relatedto energy regulation molecules. The Cochrane database was used by dividing molecules into different groups: anorexigenic / orexigenic molecules, incretins, adipokines, and myokines, all related to energy regulation and exercise induced metabolic changes. Thus, variety of molecules derived from the adipose tissue (Leptin, Adiponectin, IL-6 – Interleukin-6, TNF-α – tumor necrosis factor α), from the muscle tissue (Irisin, Myostatin), from intestine and gastric cells (YY - pancreatic peptide YY, GLP-1- Glucagon like peptide-1, GIP- Gastric inhibitory peptide, Ghrelin), from liver tissue (FGF-21- Fibroblast growth factor-21), from pancreatic cells (Amylin), and other molecules are being explored. To understand the exercise induced molecule action mechanisms and their interference, may be useful toward new pharmaceutical approaches, related to energy metabolism regulation. Key words: energy homeostasis; physiological mechanisms; exercise.