Ignjatova, Liljana
Preferred name
Ignjatova, Liljana
Official Name
Ignjatova, Liljana
Translated Name
Игњатова,Лилјана
Alternative Name
Kiteva Ignjatova L.
Лилјана Игњатова
Liljana A. Ignjatova
Ignjatova A.L.
Ignjatova L.
Liljana Ignjatova
Ignjatova Liljana
Kiteva L.
L. Kiteva
Liljana Kiteva Ignjatova
L. Ignjatova
Main Affiliation
Email
liljana.kiteva.ignjatova@medf.ukim.edu.mk
31 results
Now showing 1 - 10 of 31
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Item type:Publication, RELATION BETWEEN FAMILY HISTORY, AGE OF ONSET, RELAPSES OF THE DISORDER AND SERUM CORTISOL, DEHYDROEPIANDROSTERONE SULFAT AND THEIR RATIO IN SCHIZOPHRENIA(University Ss. Cyril and Methodius in Skopje, 2022); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Surviving in the Workplace: Conditions in Centres for the Prevention and Treatment of Drug Addiction(AU-CNS, 2019-04)Background. The European Commission has adopted a new Strategic Framework on Health and Safety at Work, 2014- 2020 and the prevention of physical accidents has recently been expanded to include the prevention of mental accidents. Aim of this study is to show the workplace situation in centres for the prevention and treatment of drug addiction (CPTDAs). Methods. The survey was conducted in 2014/2015 in 12 CPTDAs in the Republic of Macedonia. The unstandardised, work-related questionnaires were prepared by staff at the CPTDAs, in each case with a related workshop, where 31 participants were asked to analyse data through group work. Results. The number of patients participating in the study was 1,314, their average methadone dose varied from 53 to 99 mg, with 0%-60% injecting drugs in the last 30 days; 0%- 26% were employed and 0%-70% needed social help from the various centres involved. The staff complained that there were: aggressive patients, threats, offensive remarks, attempts by patients to blackmail staff members and their family, thefts carried out by patients, obstruction of the professional work being done by staff, incomplete teams, too few psychiatrists and doctors, an insufficient availability of medications for the treatment of comorbidity, an insufficient supply of buprenorphine, difficulties in referring patients to psychiatric and other hospitals, poor quality of security staff, large numbers of patients, poor quality of packaging bottles for take-home therapy, too few screening tests, inflexible working hours, organisational problems, having to face a strong social stigma, insufficient support, work to be done over the weekend for prison staff only and insufficient rest. Conclusions. Adequate care of staff is needed if our aim is to adequately cure patients. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Opioid Agonist Maintenance Treatment Outcomes—The OPTIMUS International Consensus Towards Evidence-Based and Patient-Centred Care, an Interim Report(Springer, 2023-12-26) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Screening for hepatitis C among injecting drug users in Psychiatric Hospital Skopje(Medical Faculty, Ss Cyril and Methodius University Skopje, R. Macedonia, 2017); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Association between adverse childhood experiences and health risk behaviours such as smoking, use of alcohol and substance abuse in adolescence(AU-CNS, 2016-08); Background. Adverse childhood experiences (ACEs) constitute a great proportion of the risk factors that predict poor health in later life. Aim. This study examined the association between ACEs and use of alcohol and illicit drugs, and recourse to smoking, as well as the role of gender in the association between ACEs and those health-harming behaviours. Methods. The study was retrospective and included 1,277 young adults that completed the survey on ACEs. Results. ACEs raised the likelihood of illicit drug use 2.2- to 4-fold, early initiation of smoking 2- to 3-fold, and smoking and alcohol use 1.5- to 2-fold. Compared with students without any ACEs, students with >3 ACEs showed a 2.2-fold probability of reporting illicit drug use, a 2-fold probability of starting to smoke early, and students with >4 ACEs were 60% more likely to be smokers. Almost the same percentage of female and male students smoked and used alcohol, male students smoked twice as much as female students and a significantly higher number of male students (11.3%) had drunk 6 drinks or more on a single occasion 3 or more times during the last month compared with 3.3% of female students. Significantly more male (7.6%) than female (3.6%) students had used illicit drugs in their lifetime and 3.5% of male versus 1.6% of female students had used illicit drugs more than 3 times in their life. Conclusions. ACEs increase the risks of smoking and substance use in students. Significantly more male students than female ones had used illicit drugs, and had smoked and drunk significantly greater quantities of cigarettes and alcohol. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Attachment style, self-esteem and manifest anxiety in patients undergoing treatment for opiate addiction(AU-CNS, 2016-02); Background: Insecure attachment is usually connected with lower self-esteem or with higher manifest anxiety, and can be a risk factor in those facing a variety of emotional problems, including problems associated with substance abuse. Aim of the present study is to examine the most frequent attachment style, and the level of manifest anxiety and self-esteem in patients undergoing treatment for opiate addiction compared with individuals who have no form of addiction. Methods: The sample included 47 (61%) male and 30 (39%) female, opiate addicts; they were at least 18 years old, with a mean age of 22.82 years (min. 18; max. 27; SD = 2.25 yr) and 77 mentally healthy controls, who were examined with the Coopersmith Self-Esteem Inventory (CSEI), Attachment Style Questionnaire (ASQ) and Taylor Manifest Anxiety Scale (TMAS). Comparison between the two groups focused on the percentages recorded for the various attachment styles found in each group, and the Chi-Square test was used to assess the significance of the divergences between those attachment styles in the two groups. The mean values recorded for self-esteem and manifest anxiety in the two groups were compared too, by applying the t-test. Results: The results indicate a more secure attachment style in the healthy individuals and a more fearful form of attachment in opiate-addicted individuals. The result of the present study indicated that opiate addicts are less confident and more anxious. Conclusion: Fearful attachment, low self-esteem and high manifest anxiety proved to be more frequent in opiate addicts. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Correlation between methadone dosage, cortisol plasma level and depression in methadone maintained patients(AU-CNS, 2015-12); ; Background. Opioids can affect neuroendocrine functions, with the consequence that various endocrine abnormalities, including the increased level of cortisol that can result from depression, may be acceptable in patients who use opioids. Aim of this study is to examine the correlation between methadone dosage, cortisol plasma level and depression in methadone-maintained patients. Methods. This is an analytical, cross-sectional study that included 45 patients, who were divided into two groups. The first group consisted of 10 patients (4 females and 6 males), whose doses ranged between 10 and 55 mg. The second group consisted of 35 patients (5 females and 30 males), whose doses ranged between 65 and 120 mg. To discover demographic characteristics we used medical records, to determine cortisol plasma level we relied on the Chemiluminescence Immunoassay (CLIA) method, and to determine depression we made use of the Beck depression inventory (BDI). The results were statistically analysed using a combination of descriptive methods – the t-test for independent samples, the χ² test, the Mann-Whitney U test and the Pearson coefficient of linear correlation. Results. Theresults obtained show statistically significant differences between the two groups in terms of their BDI scores, with higher scores indicating patients who were taking higher doses. There is a statistically significant correlation between cortisol plasma level and depression, but not between methadone maintenance dose and cortisol plasma level, even if a high proportion of patients in the group taking higher doses showed a higher cortisol plasma level. Conclusions. In methadonemaintained patients the methadone dose is not statistically correlated with cortisol plasma level, but some other factors in the group taking higher methadone doses tend to determine higher BDI scores. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Психолошки карактеристики на личноста кај пациенти со различен одговор на третманот на метадонско одржување(Македонско лекарско друштво = Macedonian Medical Association, 2006); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The neurophysiological correlates of cognitive functions during methadone and buprenorphine maintenance treatment: The ERP study(AU-CNS, 2021-12); ; Nada Pop-JordanovaBackground. The treatment of opioid dependence with methadone and buprenorphine is equally effective with either of the two drugs, in terms of discontinuation and retention in treatment. Buprenorphine, unlike methadone, is, however, renowned for being a drug that gives a "clear head", which is encouraging for those who are students, or who are, in any case, engaged in intellectual work. Aim. The aim of this study has been to determine if there is a difference in the neurophysiological correlates of cognitive functions in individuals treated with methadone (MMT) versus those treated with buprenorphine (BMT). Methods. The study includes 10 participants belonging to the MMT group and 10 others involved in the BMT group; both these study groups were compared with the control group after matching had been carried out for age and gender. Brain activity was recorded with the QEEG Mitsar system while study participants were performing two neuropsychological tasks. The VCPT and ECPT as modifications of the Go/NoGo paradigm were applied in order to obtain cognitive event-related potentials (ERPs) as indexes of executive functions. Besides the behavioural parameters of test performance, amplitude and latency of CNV, Cue P3, P3 Go, P3NoGo, N2Go and N2 NoGo were explored at Fz, Cz and Pz, reflecting different stages of information processing. Results. The MMT group showed longer latencies of the ERP components, and the BMT participants showed slightly better results than those of the MMT group. Still, most of the parameters did not differ significantly from those of the control group. Behavioural parameters showed significantly higher values for variables in the results for reaction time and the number of errors of omission and commission found in the competing MMT vs BMT groups, as well as the control group. Conclusions. Neurophysiological evidence suggests that methadone and buprenorphine both have positive effects on neurophysiological functions, as fewer abnormalities were found in MMT or BMT patients than in healthy controls. It has been shown that the sensitivity and specificity of detecting drug effects increase significantly when adding neurophysiological measures to task performance. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Stigma and Secrecy Coping in Individuals in Treatment for Substance Dependence in Macedonia and Slovenia(EUROPAD, 2018-05);