Darko Angjushev

Preferred name

Darko Angjushev

Translated Name

Анѓушев , Дарко

Alternative Name

Angjusev, Darko

Angusev, Darko

Angushev, Darko

Angjushev, D

Main Affiliation

darko.angjushev@medf.ukim.edu.mk

Now showing 1 - 10 of 24

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Comparative study of the effects of dexmedetomidin and midazolam on respiration and hemodynamics used during facial surgery
(MedCrave Group Kft., 2023-11-17)
Kishman, Aleksandar
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A RARE CASE OF BORDERLINE MUCINOUS TUMOR OF RIGHT OVARY IN YOUNG FEMALE CHILD. A CASE REPORT
(2024-04)
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Marija Kotevska-Angjushev
Abstract Introduction: Borderline ovarian tumors (BOTs) are extremely rare premalignant tumors in children, with an incidence of 1% of all childhood malignancies. (1) Clinical presentation is diverse, from asymptomatic to clinically significant compression of abdominal organs, great blood vessels and urinary tract. There are few reported cases in literature. (2,3) We present a rare case of BOT in young female child, successfully treated with uneventful course. Case-Report: A 12-year-old premenarchal female was admitted on Pediatric surgery department with a history of progressive abdominal distension in the last 7 months, followed by mild dysphagia and abdominal pain. Laboratory exams and serum tumor markers were unremarkable. Magnetic resonance imaging of the abdomen revealed an encapsulated, cystic right ovarian mass with huge dimensions, (37x28x18cm) suggestive for a possible ovarian tumor. Right urethra was compressed with consecutive right kidney hydronephrosis and compression of inferior vena cava. The cyst was surgically removed in total, along with 12L of clear fluid and right ovariectomy under general a nesthesia. Invasive hemodynamic monitoring was provided as perioperative course was uneventful. Postoperative analgesia was provided with Paracetamol, Metamizole and Morphine. Enteral feeding was resumed on the 2nd postoperative day. Patient was safely discharged on the 6th postoperative day. Abdominal ultrasound showed complete resolution of the kidney hydronephrosis. Pathohistological examination showed it to be a borderline mucinous tumor of the right ovary. The patient didn’t require any chemotherapy. On the 6 mouths follow up patient was free from any recurrence. Discussion: Borderline ovarian tumor is extremely rare in children. High index of suspicion is important, since clinical presentation can be unspecific. (2,4) Every female child with long lasting abdominal distension should be early examined with imaging methods such as abdominal ultrasound or MRI. Early recognition and timely surgical excision are important to avoid significant morbidity and malignant alteration. (3) Keywords: Borderline ovarian tumor, young girl, early diagnosis, premalignancy References: 1. Xu M., Wang B, Shi Y. Borderline ovarian tumor in the pediatric and adolescent population: a clinic-pathologic analysis of fourteen cases Int J Clin Exp Pathol 2020;13(5):1053-1059. 2. Ojha P, Singh Nigam J, Deshpande A, Bal Gargade C. Epithelial ovarian tumors in a premenarchal girl: a rare case report Obstet Gynecol Sci 2017;60(5):469-472. 3. Canfarotta M, Gillan E, Balarezo F, Campbell B, Tsai A, Finck C. Diagnosis, surgical treatment and management of borderline ovarian surface epithelial neoplasms: Report of 2 cases and review of literature, Journal of Pediatric Surgery Case Reports (2014), doi: 10.1016/ epsc.2014.09.009. 4. Persano G, Severi E, Cantone N, Incerti F, Ciardini E, Noccioli B. Surgical approach to giant ovarian masses in adolescents: technical considerations Pediatric Reports 2018; 10:7752 doi: 10.4081/pr.2018.7752
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NOVEL INDICATION FOR ATORVASTATIN: CHRONIC SUBDURAL HEMATOMA
(“Ss. Cyril and Methodius” University, Skopje, R.N.Macedonia, Department of Anaes thesia and Reanimation Faculty of Medicine, 2019-05)
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Kotevska-Angjushev M
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Leshi A
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The Value of Different Electrocardiographic Patterns at Hospital Admission in Predicting Clinical Outcome in Pulmonary Embolism
(iMedPub, 2021-07-02)
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Marija Kotevska Angjusheva
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Background: Literature reports the presence of several Electrocardiographic (ECG) patterns of Right Ventricular (RV) strain in acute Pulmonary Embolism (PE). These reports are inconsistent considering the prognostic value of these patterns. Aim: to evaluate the significance of ECG RV strain patterns, as well as the total number of these ECG patterns in predicting short-term (in-hospital) clinical outcome. Methods: This retrospective study was consisted of 183 patients (107 male, age: 61±14 years) with acute PE. The 12-lead ECG done at hospital admission was analysed. ECG RV strain was diagnosed in presence of one or more of following 12 patterns: tachycardia, atrial fibrillation, low QRS voltage, S1Q3T3, Q in III, aVF, right axis deviation, right bundle branch block, Qr in V1, negative T wave in inferior, precordial leads, ST elevation in inferior leads, aVR, V1 and ST depression. The outcome was defined as experience of an adverse event (in-hospital complications and death all-cause). The association of ECG patterns with outcome was evaluated by multivariable Cox hazards regression analysis. Results: During a median hospitalization time of 15 days, 41 (22.4%) adverse events occurred. Event rate was higher in patients with ≥5 ECG patterns than in <5 (63.4% vs. 0.7%; p<0.0001). Number of ECG RV strain patterns (Hazard Ratio (HR):1.7 per pattern; 95% Confidence Interval (CI): 1.1-2.6; p=0.009), ST elevation in inferior leads (HR: 8.4; 95% CI: 6.0-68.3; p=0.001) and ST depression (HR: 0.1; 95% CI: 0.03-0.6; p=0.01) were independently associated with adverse outcome. Conclusion: Number of ECG RV strain patterns, ST elevation in inferior leads, ST depression has independent value in predicting in-hospital adverse outcome in acute PE. Keywords: Acute pulmonary embolism; Electrocardiographic right ventricular strain pattern; Number of electrocardiographic right ventricular strain pattern; Ischemic patterns
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MANAGEMENT OF A GIANT LIPOMA IN THE AXILLA: A CASE REPORT
(Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, 2023)
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Toleska, Natasha
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Daskalov, Darko
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Lipomas are the most common benign mesenchymal tumors in adults.Generally,they are less than 5 cm in size but sometimes they can present as giant lipomas.Axillary region is an unusual localization for lipomas in general, especially for giant lipomas.A case of a 62-year-old male with a giant lipoma in the axillary region is presented.The tumor was located in the left axillary region beneath the pectoralis major muscle and extended all along to the scapula. It was adjacent to the axillary vessels and the brachial plexus, but did not invade the neurovascular bundle.A team of a plastic and thoracic surgeon performed the operation.The pathology report confirmed a benign lipoma weighting 454 grams and measuring 13.5x8x7 cm. Follow-up examinations (clinical examination and ultrasound) revealed no recurrence three years after the operation.The mechanism of lipoma formation is not completely clear. It includes twopotential and overlapping mechanisms in which trauma seem to have the major role.The treatment includes surgical excision or liposuction. However,excision of large lipomas can sometimes be a surgical challenge.Giant lipomas in axillary region should beremoved in order to establish the pathohistological diagnosis and to prevent possible compression of the neurovascular structures. In our opinion, surgical excision is a preferred method of treatmentbecause there is less possibility of damaging vital structures and it offers better control against local tumor recurrence.
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Mastering the technique of inferior vena cava ultrasound from transhepatic view in intensive care unit: A practical approach to the ultrasound technique, tips, and pitfalls
(SAGE Publications, 2025-09-11)
Kotevska Angjushev Marija
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Djordjevic Dikic, Ana
Background: Bedside ultrasound of inferior vena cava is used by clinician sonographers in intensive care units. Its data can impact clinical decision-making. Subcostal view is a standard view for this issue. A significant proportion of the intensive care unit patients have very difficult approach to this view. In these patients, an alternative view is a transhepatic view, feasible in nearly every intensive care unit patient. Limited data on the ultrasound technique exist in literature. Aim: In this review, we discuss in detail the technical aspects of the inferior vena cava ultrasound technique assessed from the transhepatic view, ultrasound tips, and pitfalls. Methods: A search was performed using PubMed, Google Scholar, EMBASE, and Scopus databases with the terms “inferior vena cava ultrasound,” “transhepatic view,” “right mid-axillary view,” “right lateral intercostal view,” “ultrasound technique,” “inferior vena cava pitfalls,” and inferior vena cava ultrasound tips,” “intensive care unit.” The latest articles were reviewed and this review was written using the most current information. Discussion: A standardised ultrasound approach from mid-axillary line provides optimal image acquisition. When there are difficulties finding inferior vena cava or in obesity alternative approaches should be used. Potential pitfalls during acquisition are: misidentifying the inferior vena cava; technical issues in inferior vena cava measurements; utility of the inferior vena cava data in isolation. Conclusion: Mastering the ultrasound technique from the transhepatic view offers clinicians the opportunity to perform inferior vena cava ultrasound, even in the most challenging patients. Awareness of potential pitfalls and knowledge how to avoid them is important to intensive care unit clinicians to avoid wrong decisions at the bedside.
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Evaluation of the effects of the local anesthetics on immunity during mastectomy
(Aga Khan University Hospital, 2024-02-05)
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Kishman, Aleksandar
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A Giant Eustachian Valve Protruding Into the Right Ventricle: A Case Report
(Medknow, 2014-05-21)
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Kotevska Angjushev Marija
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Lazarevski, Miroslav
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Свесност за време на општа анестезија на пациент на терапија со Beta-блокер - приказ на случај
(Macedonian Medical Association = Македонско лекарско друштво, 2013)
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Љупчо Тасевски
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Гордана Талеска
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Маја Мојсова - Мијовска
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Introduction Awareness during anesthesia is a rare but significant complication with potentially devastating psychological consequences The causes of intra operative awareness are still unclear but it is supposed that is multi factorial As a contributing factor commonly is induced the use of adrenergic blockers and ACE inhibitors Case report An years old women was hospitalized at the Clinic for Maxillofacial surgery in Skopje for operation of the cyst of the maxillary sinus In the preoperative clinical assessment was established that patient had medical history of hypertension on therapy with blockers and ACE inhibitors Preoperative and intraoperative course was without significant hemodinamically changes but after extubation patient recallwhole procedure She develops posttraumatic stress disorder Conclusion Despite precautions and good technique some cases of awareness will still occur It may not be possible to prevent every case of awareness from happening but it is possible to identify high risk cases and modify anaesthetic technique accordingly The patient should receive adequate psychological support afterwards not only in the form of a regular visit by the anaesthetist but with the referral for counselling or psychotherapy if necessary
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THE PREDICTIVE VALUE OF SERUM LACTATE ON THE OUTCOME AFTER MAJOR ABDOMINAL SURGERY
(Department of Anaesthesia and Reanimation, Faculty of Medicine, “Ss. Cyril and Methodius” University in Skopje, R.N.Macedonia, 2019-05)
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Kotevska Angjushev M
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Darko Angjushev

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