Petkovska, Rumenka
Preferred name
Petkovska, Rumenka
Official Name
Petkovska, Rumenka
Main Affiliation
Email
rupe@ff.ukim.edu.mk
27 results
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Item type:Publication, Bootstrap analysis for dissolution similarity factor f2 - bringing confidence for borderline results – a case study(Macedonian Pharmaceutical Association in cooperation with Ss. Cyril and Methodius University in Skopje, Faculty of Pharmacy., 2022) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The influence of the iodinate contrast medium during CT: Single center experience - Development of two competitive in-house methods for automated quantification of DDSB(Macedonian Pharmaceutical Association, 2019); ; ; Kroneis, ThomasDNA damage induced by ionizing radiation may ultimately lead to cell death or initiate cancer cells development. Today it is difficult to estimate what the actual damage to the human body will be, given the fact that today in the world the number of diagnostic procedures using radiation and iodine contrast media is increasing, and the existence of a number of factors that can affect the radiation dose in vivo. At the same time, development of new methods is required, which can determine in a much shorter time what will be the effect of diagnostic radiation on the DNA molecule. For these purposes we develop two competitive inhouse methods for automated quantification of DNA double strand brakes (DDSB) in peripheral blood lymphocytes: immunofluorescence determining of γH2AX with stained microscopic slides and determining the occurrence of DDSB with the flow cytometry. Our initial results shown that computed tomography (CT) can cause damage in the DNA molecule in the form of DDSB, the existence of linear dependence with the increase in low and high range of CTDI and the number of γH2AX, and that iodine contrast media can increase the occurrence of DNA double strand brakes. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Development and optimization of a generic HPLC method for the simultaneous determination of common ingredients in multi component cough and cold oral drug products using chemometrics(Macedonian Pharmaceutical Association, 2018); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Mineral enrichment of milk – nutritional benefits and future perspectives(Macedonian Pharmaceutical Association, 2020-10-29); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, A stability-indicating HPLC method for determination of folic acid and its related substances in tablets(Macedonian Pharmaceutical Association in cooperation with Ss. Cyril and Methodius University in Skopje, Faculty of Pharmacy., 2022) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Possibilities and challenges of "green" chromatographic solutions(Macedonian Pharmaceutical Association, 2022-12-31); ; ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Fc-fusion proteins: therapeutic relevance and quality assessment(Macedonian Pharmaceutical Association, 2022-12-31); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, From optimization of synbiotic microparticles prepared by spray-drying to development of new functional carrot juice(National Library of Serbia, 2014); ; Hadjieva, Jasmina<jats:p>Lactobacillus casei loaded chitosan-Ca-alginate microparticles enriched with the prebiotic fructooligosaccharide were prepared using spray-drying method associated with the polymers complexation and cross-linking with calcium. The concentrations of the formulation factors of alginate, chitosan and CaCl2 were optimized using 23 full factorial design. Experiments showed that microparticles with favorable physicochemical properties and high probiotic viability during preparation and storage could be obtained when 40 mg/g sodium alginate, 5 mg/g chitosan and 50 mg/g CaCl2 is used. Stability of L. casei during microencapsulation was identified by FTIR spectroscopy. The viability of the probiotic in the optimal formulation of synbiotic microparticles remained above the therapeutic minimum during incubation of 24 hours in simulated gastrointestinal conditions (7.67?0.4 log cfu/g) as well as after 3 months of cold storage (8.1?0.6 log cfu/g). High viability of L. casei was maintained during 6 weeks of cold storage when carrot juice was enriched with encapsulated cells. The effective preservation of L. casei into synbiotic microparticles provided production of new non-dairy functional food as an alternative of the population who is at risk of lactose intolerance.</jats:p> - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Static and dynamic quantum mechanical methods for exact interpretation of Infrared Multiple Photon Dissociation Spectra: current state and development perspectives(Macedonian Pharmaceutical Association, 2022-12-31); ; ; Pejov, Ljupco - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Chemometrics approach for optimization of capillary electrophoretic conditions for the separation of insulin analogues(Avoxa - Mediengruppe Deutscher Apotheker Gmb, 2021-11-01)
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