Sandevska, Emilija
Preferred name
Sandevska, Emilija
Official Name
Sandevska, Emilija
Main Affiliation
Email
emilija.sandevska@medf.ukim.edu.mk
38 results
Now showing 1 - 10 of 38
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Item type:Publication, THE RELEVANCE OF PREDICTING RHEUMATOID ARTHRITISSEVERITY: FACILITATING EARLY TREATMENT IN POOR PROGNOSISAND PROGNOSTIC LABORATORY MARKERS OF JOINT DAMAGE(Macedonian Association of Anatomists, 2021-07-26); ; ; ; Simultaneous testing especially of erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and rheumatoid factor (RF), which are reversible measures of inflammation, together with clinical variables of inflammatory synovitis are recommended for evaluation of disease activity. In this study 35 patients (pts) with early RA were included, while 35 pts were in the healthy control group. Pts were treated with Methotrexate at an average dose of 10 mg once weekly. RA was evaluated following the dynamics of changes of the mean values of ESR, CRP and RF. Statistical analysis showed statistically significant differences among mean values of ESR in the four time intervals (p= 0.00002). Regarding CRP, there were statistically significant differences among mean values in all four time intervals (p= 0.0428)(standard deviations were with great variations). There were no statistically significant differences of RF in the four time intervals (p= 0.573). We found high values of CRP and RF in most of the patients. In spite of the therapy with Methotrexate, disease progression continues especially in patients with elevated values of ESR, CRP and RF, which are shown as predictors for aggressive course of disease. This enables selection of high risk groups of patients for aggressive course of disease and points to the need of early and aggressive treatment. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Myocardial Infarction in Systemic Lupus Erythematosus - the Sex Specific Risk Profile(Bentham Science Publishers Ltd., 2020-12-09); ; ; Accelerated atherosclerosis is widely present in patients with systemic lupus erythematosus. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, 99mTc-MIBI GATED-SPECT Myocardial Perfusion Scintigraphy in Asimptomatic patients with Systemic Lupus Erythematosus.(Medical Facilty, Ss Cyril and Methodius University, Skopje, R. Macedonia, 2018); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Myocardial Perfusion Abnormalities in Young and Premenopausal Women with Systemic Lupus Erythematosus, Detected with 99MTC MIBI Myocardial Perfusion Scintigraphy - Prevalence and Correlation with Proatherogenic Factors(Walter de Gruyter GmbH/Macedonian Academy of Sciences and Arts, 2018-12-01); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Severe Complicated secondary antiphospholipid syndrome conjointly with lupus erythematosus -case report(Macedonian Academy of Sciences and Arts/Walter de Gruyter GmbH, 2025-01); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Satisfaction Level of Rheumatoid Arthritis Patients Enrolled in the Treatment with Subcutaneous Tocilizumab. Journal of Autoimmune Diseases and Rheumatology(Karachi: Synergy Publishers, 2020); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, ASSESSMENT OF ENZYMURIA FROM PROXIMAL RENAL TUBULE IN INFLAMMATORY SERONEGATIVE RHEUMATOID ARTHRITIS(Macedonian Medical Association/De Gruyter, 2022); ; ; ; Ana VasilevskaIntroduction. To determine the effects of non-treated seronegative rheumatoid arthritis (RA) on proximal renal tubule, sensitivity of alanine aminopeptidase (AAP), -glutamyltransferase (--GT), β2 microglobulin in urine β2M), as well as to determine the relation with rheu-matoid factor (RF) and C-reactive protein (CRP), DAS 28 - disease activity score. Methods. RF was determined by agglutination test (latex RF test, while kinetic methods were used for determination of alanine aminopeptidase (AAP) and -glutamyltransferase (-GT), as well as MEIA (micro-particle enzyme immunoassay) to determine β2 micro-globulin in urine. Samples (serum and urine) of 70 participants were examined (35 RA not treated, 35 healthy control group of patients). Results. In 35 RF negative RA, AAP enzymuria was present in 12 (34.28%) patients, -GT was present in 7 patients (20%), while β2 microglobulin was present in 3 patients (8.57%). In the healthy control group, 4 patients showed AAP positivity (11.42%), 2 patients -GT positivity (5.71%) and 1 patient showed presence of 2 microglobulin in urine (2.85). RF was not detected in any patient (0%). Conclusion. AAP has a higher sensitivity of -GT and β2 microglobulin in the detection of asymptomatic renal lesions in non-treated seronegative RA. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The utility of dual-energy X-ray absorptiometry (DXA) in the assessment of fracture risk in women with early undifferentiated psoriatic arthropathy sine psoriasis vulgaris with or without joint inflammation(Sievert Association, 2021-09); ; Psoriatic arthritis (PsA) is associated with decreased bone mineral density (BMD) and increased fracture risk. The association between BMD and fracture risk in PsA is not well elucidated. We aimed to assess BMD in an PsA cohort of patients with active disease and patients in remission, and to assess the predictive value of BMD on incidence of fractures. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, DIAGNOSTIC UTILITY OF ANTI-CCP ASSAY IN PATIENTS WITH RHEUMATOID ARTHRITIS(Macedonian Association of Anatomists and Morphologists, 2021-12); ; ; Krstevska Balkanov, SvetlanaIntroduction: The purpose of this research was to compare the diagnostic values of laboratory variables, to present quantitative evaluations of the diagnostic test with reference value for anti-cyclic citrullinated peptide (anti-CCP2) antibodies, rheumatoid factor (RF), Creactive protein (CRP), and DAS 28 index in early diagnosis of untreated rheumatoid arthritis (RA). Material and methods: Using the ELISA method of DIA-STAT™ Anti CCP (Axis-Shield Diagnostics), sera of 70 participants were examined (35 untreated patients with RA and 35 subjects from the healthy control group). RF and CRP were determined with the agglutination test (Latex test) in the same participants. At the same time, we determined the sensitivity, specificity, predictive value for positive and negative test and accuracy. Results: Presence of anti-CCP 2 antibodies was 65.71%, 23/35 patients, while RF was present in 17/35 (48.57%). Twelve patients were anti-CCP2 and RF positive, 11 were antiCCP2 positive, but RF negative. Five patients were anti-CCP2 negative and RF positive. In the healthy control group, one patient was anti-CCP2 positive, while 2 patients were RF positive. Conclusion: Anti-CCP2 antibodies have higher sensitivity and specificity than RF in early RA - Some of the metrics are blocked by yourconsent settings
Item type:Publication, C-REACTIVE PROTEIN - THE MOST USEFUL REACTANT OF ACUTE PHASE IN RHEUMATOID ARTHRITIS(Macedonian Association of Anatomists, 2023); ;