Pavkovikj, Marica
Preferred name
Pavkovikj, Marica
Official Name
Pavkovikj, Marica
Alternative Name
Pavkovic, Marica
Main Affiliation
Email
marica.pavkovic@medf.ukim.edu.mk
pavkovicm@yahoo.com
65 results
Now showing 1 - 10 of 65
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Item type:Publication, Special Conditions in Venous Thrombembolism - Case Series(Macedonian Academy of Sciences and Arts/Walter de Gruyter GmbH, 2019-10-01); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Tumor necrosis factor gene polymorphisms in adult patients with autoimmune hemolytic anemia(Wiley, 2017-06); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, CML-053 Health-Related Quality of Life in Macedonian Patients with Chronic Myeloid Leukemia Treated with Tyrosine Kinase Inhibitors: EQ-5D-5L Assessment(Elsevier BV, 2024-09); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Autoimmune hemolytic anemia in a covid 19 patient(Department of Anaesthesia and Reanimation, Faculty of Medicine, "Ss. Cyril and Methodius" University, Skopje, 2021-10); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Long-Term Efficacy of Treatment in Elderly Patients With Hodgkin Lymphoma: A Retrospective Analysis(Elsevier BV, 2024-09); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, FC gamma receptor polymorphisms in patients with immune thrombocytopenia(Taylor & Francis, 2018-04); ; ; ; Aleksandar StojanovicImmune thrombocytopenia (ITP) is an autoimmune blood disease of unknown etiology. The aim of our study was to investigate a possible role of FCGR2A and FCGR3A polymorphisms in the development of primary ITP. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Health-Related Quality of Life in Macedonian Patients with Chronic Myeloid Leukemia Treated with Tyrosine Kinase Inhibitors: EQ-5D-5L Assessment(Elsevier BV, 2024-09); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, HL-210 Long-Term Efficacy of Treatment in Elderly Patients With Hodgkin Lymphoma: A Retrospective Analysis(Elsevier BV, 2024-09); ; ; Genadieva Stavrik, Sonja - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Bgl II POLYMORHISM OF THE α2β1 INTEGRIN GENE IN MACEDONIAN POPULATION(2010-06-15); ; ; Glycoprotein (GP) Ia/IIa or α2β1 integrin is a platelet receptor for collagen and it mediates platelet adhesion to vascular subendothelium and is involved in thromb formation. Genetic polymorphism of α2β1 known as Bgl II affects the density of platelet GP Ia/IIa receptor on the platelet surface. Recent studies had shown relationship between this polymorphism and the risk of myocardial infarction, stroke, as well as diabetic retinopathy. The aim of this study was to determine the frequency of this polymorphism in Macedonian healthy population. We genotyped 217 healthy Macedonian individuals using the method of RFLP (restriction fragment length polymorphism). The allele frequencies in this study were 0.32 for Bgl II (+) allele and 0.67 for Bgl II (-). Distribution of Bgl II genotypes in Macedonian population was Bgl II (+/+) =16/217 (7.3%), Bgl II (+/-) =107/217 (49.3%) and Bgl II (-/-) =94/217 (43.3%). Our results showed a slightly lower proportion of the Bgl II (+) allele (0.32) in Macedonian population, but not significantly different from other Caucasian population. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Changes of the lysozyme level in the serum and organs of the aging rats("Ss Cyril and Methodius"University, Faculty of Medicine, Skopje, Institute for Immunology, 1997); ; ; ; The enzyme lysozyme or muramidase (E.C.3.2.2.17) catalyzes the hydrolysis 1,4-b glycoside linkages between N-acetylmuraminic acid and N-acetyl glucosamine in peptidoglycans. Lysozyme is part of the congenital immunity and has bactericide activity maily on gram (+) bacteria, although there is evidence of his activity on gram (-) bacteria, too. Lysozyme catalyzes not only the breakdown of the peptidoglucan from the bacterial wall, but it also influences on the complement as well as on the synthesis of the antibodies. The aim of this paper was to find out the changes in the activity of lysozyme during the process of aging. The investigation was performed on 68 male Wistar rats divided into 6 groups. The first group (n=13) was 1 month old, the second (n=13) was 3 months old, the third (n=11) 6 months, fourt (n=12) 9 months, the fifth (n=12) 12 months and the sixt (n=7) was 18months old.The lysozyme activity was examined in the serum and organs on lysoplates modifided for our conditions. The analyses have shown that the present changes in the lysozyme activity in the epididymis, mesenterium and testis are not statisticaly significant. The activity of lysozyme in te serum is significantly increased (p<0.005) in the second group whereas in the spleen (p<0.01) and in the kidney (p<0.001)it was higher in the fourth group. Lysozyme showed significant increase (p<0.007) in the lungs in the second and fourth group and in the thymus in the fifth group (p<0.001). The results have shown that the process of the aging has influenced on the lysozyme activity in certain tissues. This activity is increased and is very apparent in the serum as early as in third month, whereas in the other tissues it appears in the ninth month.Thera are still no reliable data for the appearance of these changes, but there is no mutual mechanism for all of them.