Faculty of Veterinary Medicine
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Skopje
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Item type:Publication, Health benefits and risks of fermented foods-the PIMENTO initiative(Frontiers Media SA, 2024) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Using Species-Specific Protocols for the Welfare Assessment of Elephants in the Skopje Zoo(Macedonian Veterinary Review, 2022-05); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Impact of cholesteroldietonmitochondrial 18 kda translocator protein (TSPO) in the aorta of apoEknockout mice.(2009); Dosic-Markovska B - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Analysis of 226Ra, 232Th 40К and 137Cs in samples of soil from some areas of Republic of Macedonia by using gamma spectrometry(Mac Vet Rev, 2013-10-15); ; ; Stojanovska-Dimzoska Biljana - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Virulence genes of Escherichia coli vaginal isolates associated with postpartum dysgalactia syndrome in sows(Journal of Swine Health and Production, 2021-11); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Seroprevalence of Toxoplasma gondii infection in farmed saws in Republic of Macedonia(Faculty of Veterinary medicine in Skopje, 2016-09); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Anti-inflammatory properties of L. casei loaded whey protein-alginate microparticles in animal model of colitis(2014) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Histopathological changes of the kidneys in T-2 mycotoxicosis in broilers(2014) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Histopathological and immunohistochemical examibation on the colon of rats with TNBS-induced colitis after administration of functional food containing microencapsulated synbiotic(2016); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Field surveys in Croatia and North Macedonia reveal two novel phleboviruses circulating in sandflies(Microbiology Society, 2021-11); Sandfly-borne phleboviruses are distributed widely throughout the Mediterranean Basin, presenting a threat to public health in areas where they circulate. However, the true diversity and distribution of pathogenic and apathogenic sandfly-borne phleboviruses remains a key issue to be studied. In the Balkans, most published data rely on serology-based studies although virus isolation has occasionally been reported. Here, we report the discovery of two novel sandfly-borne phleboviruses, provisionally named Zaba virus (ZABAV) and Bregalaka virus (BREV), which were isolated in Croatia and North Macedonia, respectively. This constitutes the first isolation of phleboviruses in both countries. Genetic analysis based on complete coding sequences indicated that ZABAV and BREV are distinct from each other and belong to the genus Phlebovirus, family Phenuiviridae. Phylogenetic and amino acid modelling of viral polymerase shows that ZABAV and BREV are new members of the Salehabad phlebovirus species and the Adana phlebovirus species, respectively. Moreover, sequence-based vector identification suggests that ZABAV is mainly transmitted by Phlebotomus neglectus and BREV is mainly transmitted by Phlebotomus perfiliewi. BREV neutralizing antibodies were detected in 3.3% of human sera with rates up to 16.7% in certain districts, demonstrating that BREV frequently infects humans in North Macedonia. In vitro viral growth kinetics experiments demonstrated viral replication of both viruses in mammalian and mosquito cells. In vivo experimental studies in mice suggest that ZABAV and BREV exhibit characteristics making them possible human pathogens.