Faculty of Pharmacy
Permanent URI for this communityhttps://repository.ukim.mk/handle/20.500.12188/17
Browse
39 results
Search Results
- Some of the metrics are blocked by yourconsent settings
Item type:Publication, Comparative Modeling Approaches in the Development and Evaluation of Silica Nanoparticles as 5-Fluorouracil Carriers using PLS, DoE and GBR(Springer Science and Business Media LLC, 2025-11-24); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Comparative Modeling Approaches in the Development and Evaluation of Silica Nanoparticles as 5-Fluorouracil Carriers using PLS, DoE and GBR(Springer Science and Business Media LLC, 2025-11-24); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, 3D printed extended-release hydrochlorothiazide tablets(Elsevier BV, 2025-03-01); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Micro-Raman Spectroscopy for Detection of Label-Free and Oil Red O Labeled PEGylated Nanoliposomes in hCmec/D3 Cell Internalization Studies(Croatian Chemical Society, 2022-12); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Comparative Studies of the Uptake and Internalization Pathways of Different Lipid Nano-Systems Intended for Brain Delivery(MDPI AG, 2023-08-03); Lipid nano-systems were prepared and characterized in a series of well-established in vitro tests that could assess their interactions with the hCMEC/D3 and SH-SY5Y cell lines as a model for the blood-brain barrier and neuronal function, accordingly. The prepared formulations of nanoliposomes and nanostructured lipid carriers were characterized by z-average diameters of ~120 nm and ~105 nm, respectively, following a unimodal particle size distribution (PDI < 0.3) and negative Z-potential (-24.30 mV to -31.20 mV). Stability studies implied that the nano-systems were stable in a physiologically relevant medium as well as human plasma, except nanoliposomes containing poloxamer on their surface, where there was an increase in particle size of ~26%. The presence of stealth polymer tends to decrease the amount of adsorbed proteins onto a particle's surface, according to protein adsorption studies. Both formulations of nanoliposomes were characterized by a low cytotoxicity, while their cell viability was reduced when incubated with the highest concentration (100 μg/mL) of nanostructured lipid formulations, which could have been associated with the consumption of cellular energy, thus resulting in a reduction in metabolic active cells. The uptake of all the nano-systems in the hCMEC/D3 and SH-SY5Y cell lines was successful, most likely following ATP-dependent internalization, as well as transport via passive diffusion. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Nanotechnology - a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer(BEILSTEIN INSTITUT, 2023-02-22) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Formulation and characterization of snail slime-chitosan microparticles with herbal extracts intended for treatment of chronic wounds(2022); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Evaluation of antioxidant properties of herbal mixture and CBD oil for the treatment of chronic wound(Macedonian pharmaceutical association, 2022); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Pharmacy students' experience during the Covid-19 pandemic and its impact on their health, academic endeavors and overall perceptions-a study(Macedonian pharmaceutical association, 2022); Slaveska Raicki, Renata - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Knowledge, opinions and attitudes of the general population in the Republic of N. Macedonia about vaccines and vaccination(Macedonian pharmaceutical association, 2022); ; ;