Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12188/9885
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Maja Tankoska | en_US |
dc.contributor.author | Avdi Murtezani | en_US |
dc.contributor.author | Konstandina Kuzevska-Maneva | en_US |
dc.contributor.author | Marina Krstevska-Konstantinova | en_US |
dc.date.accessioned | 2021-01-15T09:26:59Z | - |
dc.date.available | 2021-01-15T09:26:59Z | - |
dc.date.issued | 2020-02-20 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12188/9885 | - |
dc.description.abstract | There is a small number of studies that have reported abnormalities in endocrine function after a long-term gonadotropin-releasing hormone agonist (GnRHa) treatment in girls. This treatment is considered as safe and effective by most authors. We report our second case of unusual outcome of long-term GnRHa therapy in a girl with central precocious puberty (CPP) of idiopathic or familial etiology. She has received monthly depot of injections of triptorelin for a time period of 4 years. We have examined thyroid function by measuring serum levels of thyrotropin (TSH), thyroxine (T4), thyroid antibodies and ultrasound of thyroid gland. At the age of 11 years she developed a mild goiter and presented with autoimmune thyroiditis, having elevated thyroid antibodies and ultrasound of thyroid gland typical for Hashimoto thyroiditis. Having in mind these two cases, we suggest a closer monitoring of thyroid function in girls with CPP, before and during therapy with GnRH agonist. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Институт за јавно здравје на Р Северна Македонија = Institute of Public Health of R North Macedonia | en_US |
dc.relation.ispartof | Archives of Public Health = Архиви на јавното здравје | en_US |
dc.title | Autoimmune thyroiditis after long term gonadotropin- releasing hormone agonist treatment for central precocious puberty: case report | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.3889/aph.2020.4477 | - |
dc.identifier.url | https://www.id-press.eu/aph/article/download/4477/4314 | - |
dc.identifier.url | https://www.id-press.eu/aph/article/download/4477/4314 | - |
dc.identifier.volume | 12 | - |
dc.identifier.issue | 1 | - |
dc.identifier.fpage | 62 | - |
dc.identifier.lpage | 65 | - |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
Appears in Collections: | Faculty of Medicine: Journal Articles |
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