Histological positivity of resection margins as risk factor for occurrence of early postoperative complications in patients undergoing ileocolic resection due to complications from Crohn's disease

Abstract

Crohn’s disease (CD) is a chronic inflammatory condition of the gastrointestinal tract that can lead to strictures, inflammatory masses, fistulas, abscesses, hemorrhage and cancer. This disease commonly affects the small bowel, colon, rectum or anus. Less commonly, it affects the stomach, esophagus and mouth. Often, the disease affects multiple areas of the gastrointestinal tract simultaneously. The cause of CD is not known and there is no curative treatment. Current medical and surgical treatments are effective in controlling the disease, but even with optimal treatment, recurrences and relapses are frequent.Various risk factors specific for the patients withconditions related to the CD can influence the outcome of the surgical treatment in the postoperative period. Those risk factors can be preoperative laboratory markers of inflammation such as WBC and CRP values, phlegmona of the anterior abdominal wall, preoperative interintestinal abscessand positive resection margins.We presentourinitial 5-year results ofthe Clinic for Digestive Surgery in Skopje,regarding the impact of histological resection margins onthe emergence of the early postoperative complications in patients undergoing ileocolic resection due to Crohn's disease. The statistical program SPSS 19.0was used for quantitative analysis and processing of the data.All statistically significant differences were discussed at a statistically significant level of p <0.05