Respiratory symptoms, COPD, and work ability in workers exposed to phenolic resins

Abstract

Objective. To evaluate the prevalence of respiratory symptoms and COPD, and level of work ability index in workers exposed to phenolic resins. Methods. This cross-sectional study involved 45 male workers exposed to phenolic resins (mean age 48.2±7.5 years, mean exposure duration 21.3±8.6 years, 40% smokers). Additionally, 50 male office workers (mean age 46.2±8.2 years, mean job duration 20.7±9.2 years, 38% smokers) were examined as a control. Evaluation of examined subjects included completion of a questionnaire on respiratory symptoms in the last 12 months, spirometry, job exposure matrices for evaluation of occupational exposure, and Work Ability Index (WAI). Results. Compared with office workers, exposed workers had more frequently cough (17.8% vs. 6%), phlegm (15.6% vs. 6%), and dyspnoea (13.3% vs. 6%) (p<0.05). Spirometry showed significantly lower MEF75, MEF50, and MEF25 in exposed workers. COPD was significantly more frequent in exposed workers (13.3% vs. 6%, p<0.05). Regular exposure to phenolic resins significantly increased COPD risk (OR=2, 95%CI 1.7-2.3). Mean WAI score was significantly lower in exposed workers (34.5±5.2) than in controls (44.9±6.5) (t=-7.9; p<0.01). Mean WAI score was significantly lower in workers with COPD in both groups. Conclusion. Our data emphasize important role of occupational exposure to phenolic resins in the development of respiratory symptoms, COPD, and WAI reduction.