PREVALENCE OF BACTERIAL VAGINOSIS

Abstract

Bacterial vaginosis is a disorder in the composition of the vaginal flora that leads to a decrease in the number of hydrogen peroxide-producing lactobacilli and a predominance of various anaerobic bacteria. A retrospective cohort study, performed on a series of 192 patients aged 20 to 59 years, divided into two groups: study and control. The study group included 128 sexually active women with a Pap smear that showed the presence of a squamous intraepithelial lesion or squamous invasive cervical cancer. The control group included 64 sexually active women with a normal PAP test. In all women we done: Nugent's score system, and as indicated, all women in the study group and colposcopic cervical biopsy with endocervical curettage for histopathological analysis. Bacterial vaginosis was detected in 43.75% of patients with squamous cell abnormalities of the cervix and in 12.50% of patients with normal cervical cytology. Data analysis showed: correlation between the presence of bacterial vaginosis and the occurrence of squamous cell abnormalities of the cervix (chi-square test = 4.1906, p <0.05); increase in the presence of bacterial vaginosis with increasing cytopathological (chi-square test = 12,198, p˂0.05) and histopathological (chi-square test = 6.3434, p˂0.05) degree of cervical lesion and that bacterial vaginosis was most common in patients under 30 years of age (57.14%; 16/28). There is a statistically significant correlation between the modalities, the presence of bacterial vaginosis and the absence of bacterial vaginosis between the study and the control group (chi-square test = 18.75, p˂0.05). The percentage difference between the modalities presence of bacterial vaginosis and absence of bacterial vaginosis between the study and the control group was statistically insignificant for p˃0.05 (p = 0.1863, t = 1.9799, 95% CI = -138.8260-54,260). Our study showed an association between bacterial vaginosis and squamous cell abnormalities of the cervix.