The use of topical dorzolamide in uveitis patients with CME

Abstract

Purpose: THE AIM OF THIS PILOT STUDY WAS TO ASSESS THE EFFECTIVENESS OF DORZOLAMIDE FOR THE MANEGEMEND OF INFALMATORUM CHRONIC CYSTOID MACULAR EDEMA. Method: TEN PATIENTS (16 EYES )WITH UVEITIS-INDUCED CME RECEIVED 2% DORZOLAMIDE DROPS T.I.D. IN ADDITION TO THE THEIR NORMAL MEDICATION.AT EACH VISIT,BEST CORECTIED VISUAL ACUITY WAS MEASURED AND A FLUORESCEIN ANGIOGRAM WAS OBTAINED. Results: NO PATIENT SHOWED WORSENING OF THE CLINICAL FINDINGS.VISUAL ACUITY WAS IMPROVED BY 2 LINES OR BETTER IN 50%. VISUAL ACUITY COULD NOT BE IMPROVED IN THE REST OF THEM.IMPROVEMENT IN THE AMOUNT OF FLURESCEIN LEAKAGE COULD BE OBSERVED IN 12 EYES (7 PATIENTS). Conclusions: TOPICAL DORZOLAMIDE MAY INFLUENCE THE OUTCOME OF CME IN UTEITIS PATIENTS IN ADDITION TO ITS OCULAR HIPOTENSIVE EFFECTS.