Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12188/1619
DC Field | Value | Language |
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dc.contributor.author | Gulaboski, Rubin | en_US |
dc.contributor.author | Bogeski, Ivan | en_US |
dc.contributor.author | Kokoskarova, Pavlinka | en_US |
dc.contributor.author | Haeri, Haleh H | en_US |
dc.contributor.author | Mitrev, Sasa | en_US |
dc.contributor.author | Stefova, Marina | en_US |
dc.contributor.author | Stanoeva, Jasmina Petreska | en_US |
dc.contributor.author | Markovski, Velo | en_US |
dc.contributor.author | Mirčeski, Valentin | en_US |
dc.contributor.author | Hoth, Markus | en_US |
dc.contributor.author | Kappl, Reinhard | en_US |
dc.date.accessioned | 2019-03-11T09:44:11Z | - |
dc.date.available | 2019-03-11T09:44:11Z | - |
dc.date.issued | 2016-10 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12188/1619 | - |
dc.description.abstract | Coenzyme Q-0 (CoQ-0) is the only Coenzyme Q lacking an isoprenoid group on the quinoid ring, a feature important for its physico-chemical properties. Here, the redox behavior of CoQ-0 in buffered and non-buffered aqueous media was examined. In buffered aqueous media CoQ-0 redox chemistry can be described by a 2-electron-2-proton redox scheme, characteristic for all benzoquinones. In non-buffered media the number of electrons involved in the electrode reaction of CoQ-0 is still 2; however, the number of protons involved varies between 0 and 2. This results in two additional voltammetric signals, attributed to 2-electrons-1H(+) and 2-electrons-0H(+) redox processes, in which mono- and di-anionic compounds of CoQ-0 are formed. In addition, CoQ-0 exhibits a complex chemistry in strong alkaline environment. The reaction of CoQ-0 and OH(-) anions generates several hydroxyl derivatives as products. Their structures were identified with HPLC/MS. The prevailing radical reaction mechanism was analyzed by electron paramagnetic resonance spectroscopy. The hydroxyl derivatives of CoQ-0 have a strong antioxidative potential and form stable complexes with Ca(2+) ions. In summary, our results allow mechanistic insights into the redox properties of CoQ-0 and its hydroxylated derivatives and provide hints on possible applications. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier BV | en_US |
dc.relation.ispartof | Bioelectrochemistry (Amsterdam, Netherlands) | en_US |
dc.subject | Coenzyme Q-0 Voltammetry EPR Hydroxyl benzoquinones Antioxidants Calcium binding | en_US |
dc.title | New insights into the chemistry of Coenzyme Q-0: A voltammetric and spectroscopic study | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1016/j.bioelechem.2016.05.008 | - |
dc.identifier.url | https://api.elsevier.com/content/article/PII:S156753941630069X?httpAccept=text/plain | - |
dc.identifier.url | https://api.elsevier.com/content/article/PII:S156753941630069X?httpAccept=text/xml | - |
dc.identifier.volume | 111 | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
crisitem.author.dept | Faculty of Natural Sciences and Mathematics | - |
Appears in Collections: | Faculty of Natural Sciences and Mathematics: Journal Articles |
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