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http://hdl.handle.net/20.500.12188/9608| Title: | The antioxidant N-acetylcysteine prevents accelerated atherosclerosis in uremic apolipoprotein E knockout mice | Authors: | Ivanovski, Ognen Szumilak, Dorota Nguyen-Khoa, Thao Ruellan, Nadya Phan, Olivier Lacour, Bernard Descamps-Latscha, Béatrice Drüeke, Tilman B Massy, Ziad A |
Issue Date: | Jun-2005 | Publisher: | Elsevier BV | Journal: | Kidney international | Abstract: | Cardiovascular disease is the most frequent cause of mortality in chronic renal failure (CRF). Therefore, it is important to identify appropriate treatment measures. The antioxidant N-acetylcysteine (NAC) has been shown to reduce cardiovascular events in hemodialysis patients. Here we examine a possible direct effect of NAC supplementation on uremia-enhanced atherosclerosis in apolipoprotein E-deficient (apoE(-/-)) mice. | URI: | http://hdl.handle.net/20.500.12188/9608 | ISSN: | 0085-2538 | DOI: | 10.1111/j.1523-1755.2005.00332.x |
| Appears in Collections: | Faculty of Medicine: Journal Articles |
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