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dc.contributor.authorKostadinova Petrova, Irenaen_US
dc.contributor.authorMitevska, Elidaen_US
dc.contributor.authorBiljana Janeskaen_US
dc.description.abstractBACKGROUND:In forensics bruises as injuries take an important part in the interpretation of the causes of death. Since activating the inflammatory response of the body in their formation, histological analysis of the bruised tissue can provide data on the determination the time when the injury occurred.AIM:The aim of this study is to compare the histological features of 1-day and 5-days old bruises.MATERIAL AND METHODS:Bruised human skin samples, 1-day old in group A and 5-day-old in group B, obtained at autopsy from individuals who died from a violent death, were analyzedin this study. The qualitativemicroscopic analysis was performedon serial paraffin sections of tissues stained with Hematoxylin-eosin and Pearls Prussian Blue method, using a light microscope connected to a digital camera.RESULTS:Qualitative histological analysis of the studied group A presented with fresh bruises, less than 24 hours old, showed ruptured smaller vessels and extravasated red blood cells intheconnectivetissue of the skin, with subsequent expansion and infiltration of fibrous septa of the skin. In the area of bleeding an initial infiltration by macrophages was observed. In the studied group B, presented with bruises 3-7 days old, histological analysis showed a marked presence of hemosiderin-ladenmacrophages and presence of hematoidin granules in the area of bleeding, as well as ruptured small blood vessels and red blood cells extravasation in the dilated fibrous septa. CONCLUSION: A detailed analysis of tissue changes in bruises every day from the initiation until their recovery, a detailed description of the histological finding can be given, which will be supported in the precise determination of the age of the injuries themselvesen_US
dc.publisherID Design 2012/Scienfitic Foundation SPIROSKIen_US
dc.relation.ispartofOpen Access Macedonian Journal of Medical Sciencesen_US
dc.subjecthistological characteristicsen_US
dc.titleHistological Characteristics of Bruises with Different Ageen_US
item.fulltextWith Fulltext- of Medicine- of Medicine-
Appears in Collections:Faculty of Medicine: Journal Articles
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