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Title: Red Blood Cell Variables in Children and Adolescents regarding the Age and Sex
Authors: Jasmina Pluncevic Gligoroska 
Gontarev, Serjoza
Shukova Stojmanova, Daniela
Dejanova, Beti 
Todorovska, Lidija 
Manchevska, Sanja 
Keywords: red blood cells,
hematological indices,
Issue Date: Apr-2019
Publisher: Tehran University of Medical Sciences
Journal: Iranian Journal of Public Health
Abstract: Background: This study aimed to assess the basic red blood cell variables and hematological indices in children and adolescents and analyze the differences regarding age and sex. Methods: Overall, 320 young participants, age 8 to 18 years, were enrolled at Laboratory of sport’s medicine, Medical Faculty, Skopje during the 2016. Capillary blood samples were drawn and following hematologic parameters were measured: the red blood cell count (RBC), hemoglobin concentration (Hb), hematocrit level (Hct) and hematological indexes: mean corpuscular volume (MCV), mean hemoglobin concentration (MCH), mean corpuscular hemoglobin concentration (MCHC) and red cell distribution width (RDW). Results: RBC variables in male group showed high statistical level of significance between age different groups (P=0.001) for all studied parameters except MCHC (P=0.423) and RDW (P=0.174). ANOVA test and multivariate tests in female group showed that there was no significant difference for all hematological parameters between age different groups. Regarding the sex differences, male participants had significantly higher red blood count (P<0.001), hemoglobin content (P<0.001) and hematocrit (P<0.001). Conclusion: Hematological parameters in adolescent as inhomogeneous population are not quantified sufficiently, especially hematological indices. RBC variables, regardless of the age, differ very much between male and female subjects, in favor of the male subjects. Hematological indices were insignificantly higher in males. Regarding the age RBC variables showed significant inter-groups differences only within male adolescents. While with girls, ages span 8 to 18 yr, we did not find significant differences for most of the hematological variables.
Appears in Collections:Faculty of Medicine: Journal Articles

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