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Title: Granular cell tumor of the breast: a case report and review of literature
Authors: Filipovski, Vanja
Banev, Saso
Janevska, Vesna 
Dukova, Blagica 
Keywords: granular cell tumor
rare benign neoplasm
cytoplasmic granule
Issue Date: 10-Aug-2009
Publisher: BioMed Central
Journal: Cases Journal
Abstract: A 22-year-old female patient presented with a breast mass lesion with a clinical suspicion of a fibroadenoma. Histological evaluation revealed a rare benign neoplasm - granular cell tumor. Granular cell tumor is rare neoplasm that may arise in virtually any body site, and in 5% it occurs in the breast. The histogenesis of this tumor is still rather controversial and currently the most acceptable theory is a Schwann cell origin. The main histological feature is granular cytoplasm of the tumor cells. From a clinical point of view there is a similarity between granular cell tumor and mammary carcinoma on mammography and ultrasound. Pathohistologically, sometimes, differential diagnostic difficulties exist concerning apocrine carcinoma, histiocytic lesions and metastatic neoplasms.
Appears in Collections:Faculty of Medicine: Journal Articles

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