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Title: Effect of synbiotic soymilk on intestinal microbiota and lipid profile in adult spontaneously hypertensive rats
Other Titles: Влијание на ферментирано соја млеко на цревната микрофлора и липиден профил кај спонтано хипертензивни стаорци
Authors: Jurhar Pavlova, Maja 
Panovski, Nikola 
Mladenovska K
Petreska Ivanovska T
Tosevska K 
Cekovska, Svetlana 
Petrovska, Milena 
Keywords: L. casei
Synergy 1
spontaneously hypertensive rats
intestinal microbiota
lipid profile
Issue Date: 2015
Publisher: SHMSHM/AAMD
Journal: MEDICUS
Abstract: The aim of the study was to examine the influence of a new synbiotic fermented soymilk on microbiota and lipid profile in rats. In addition body weight, and stool consistency were also investigated. Мaterial and methods: Soy milk fortified with prebiotic (Synergy1) was fermented with probiotic L casei-01. The viable L casei-01 counts in fermented end product were 11.49±0.13 log10 cfu mL-1. 1 ml of synbiotic fermented soymilk was administered daily to six months old male spontaneously hypertensive rats (SHR’s). After 4 weeks treatment, jejunal, illeal, colon and fecal samples were analyzed for Lactobacillus spp, E coli, Enterococcus spp and Staphylococcus spp viable counts. Cholesterol, triglycerides and HDL concentrations in blood samples were determined. Results: The significantly higher viable Lactobacillus spp counts followed with significantly decreased E coli and Enterococcus spp counts in all samples were observed in treated vs. control group. Staphylococcus spp counts were significantly decreased in colon samples. The difference in lipide profile was insignificant. In conclusion, synbiotic fermented soymilk significantly improved the composition of the intestinal microbiota in rats. The lipid profile of healthy adult spontaneously hypertensive rats was not altered.
ISSN: 1409-6366
Appears in Collections:Faculty of Medicine: Journal Articles

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