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Title: Circulation of Crimean-Congo Hemorrhagic Fever Virus in the former Yugoslav Republic of Macedonia revealed by screening of cattle sera using a novel enzyme-linked immunosorbent assay
Authors: Mertens, Marc
Vatansever, Zati
Mrenoshki, Slavcho 
Krstevski, Kiril 
Stefanovska, Jovana 
Djadjovski, Igor
Cvetkovikj, Iskra 
Farkas, Robert
Schuster, Isolde
Donnet, Fabien
Comtet, Loic
Tordo, Noël
Ben Mechlia, Mohamed
Balkema-Buschmann, Anne
Mitrov, Dine 
Groschup, Martin H
Issue Date: Mar-2015
Publisher: Public Library of Science (PLoS)
Journal: PLoS neglected tropical diseases
Abstract: There are only few assays available for the detection of Crimean-Congo Hemorrhagic Fever Virus (CCHFV)-specific antibodies in animals, and data about diagnostic sensitivity and specificity are incompletely documented for most of these tests. This is unfortunate since CCHFV antibodies in animals can be used as indicator for virus circulation in a geographic area and therewith potential risk of human exposure. This paper therefore reports on a novel ELISA for the detection of CCHFV-specific antibodies in cattle and on its application for testing ruminant sera from the Former Yugoslav Republic of Macedonia.
DOI: 10.1371/journal.pntd.0003519
Appears in Collections:Faculty of Veterinary Medicine: Journal Articles

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