Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12188/33517
Title: Podocalyxin and kidney diseases
Authors: Kostovska, Irena 
Keywords: podocalyxin
podocyte
renal glomerulus
diabetic nephropathy
kidney diseases
Issue Date: Apr-2025
Publisher: Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine
Journal: The Ukrainian Biochemical Journal
Abstract: Selectivity of blood filtration by the renal glomerulus is largely determined by the presence in its visceral epithelium of the terminally differentiated “octopus-like” cells called podocytes. Podocalyxin (PoDXL) is a major transmembrane glycoprotein located on the podocytes’ apical surface. Recently, the appearance of PoDXL in urine has been considered a marker of nephropathy. the purpose of this review article is to analyze the data of studies on the structural and functional features of podocalyxin and its value in diagnostic, prognostic and potential therapeutic relevance in most common kidney diseases.
URI: http://hdl.handle.net/20.500.12188/33517
ISSN: 2413-5003
Appears in Collections:Faculty of Medicine: Journal Articles

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