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http://hdl.handle.net/20.500.12188/33517
Title: | Podocalyxin and kidney diseases | Authors: | Kostovska, Irena | Keywords: | podocalyxin podocyte renal glomerulus diabetic nephropathy kidney diseases |
Issue Date: | Apr-2025 | Publisher: | Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine | Journal: | The Ukrainian Biochemical Journal | Abstract: | Selectivity of blood filtration by the renal glomerulus is largely determined by the presence in its visceral epithelium of the terminally differentiated “octopus-like” cells called podocytes. Podocalyxin (PoDXL) is a major transmembrane glycoprotein located on the podocytes’ apical surface. Recently, the appearance of PoDXL in urine has been considered a marker of nephropathy. the purpose of this review article is to analyze the data of studies on the structural and functional features of podocalyxin and its value in diagnostic, prognostic and potential therapeutic relevance in most common kidney diseases. | URI: | http://hdl.handle.net/20.500.12188/33517 | ISSN: | 2413-5003 |
Appears in Collections: | Faculty of Medicine: Journal Articles |
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File | Size | Format | |
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Kostovska Review UBJ.pdf | 1.05 MB | Adobe PDF | View/Open |
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