Bilateral near-total calcification of vas deferens in young male

Abstract

Bilateral calcification of vas deferens is an uncommon condition, particularly in young males. Only a few case reports are published for this condition in young males, and what they have in common is diabetes mellitus. A 33-year old man presented with dull pain in the right inguinal region. The patient has had history of insulin dependent diabetes mellitus type I for thirty years. He complained of dull pain in the right inguinal region. The pain started about ten years ago, but it has grown stronger and more frequent in the last two months. CT scan was performed which confirmed the presence of calcification along almost the entire length of the vas deferens, starting from testes to the prostate with prostatic calcification. Androflor Screen test was made to detect the total bacterial DNA, and pathological levels of Bacteroides spp./Porphyromaonas spp./Prevotella spp. were detected and antibiotic treatment was prescribed. Calcification of the vas deferens is relatively specific to DM and 70% of males who had vas calcification also had diabetes. There are other etiologies associated with the calcification of vas deferens such as chronic infections and inflammations, but it can also be seen as a manifestation of aging. The calcification may also be associated with infertility. Pathologically, diabetic vas deferens calcification can be differentiated from the chronic inflammatory type. Chronic inflammatory calcification is usually intraluminal which may be unilateral and segmental, while the calcification seen in diabetes is usually mural and symmetrical. Unfortunately, currently there are no available curative treatment option for this condition. Diabetes is the primary cause of bilateral calcification of the vas deferens in young males, which can lead to infertility. Bearing this in mind, it's important to inform patients about the associated risks and advise them to take necessary precautions.