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http://hdl.handle.net/20.500.12188/30935
Title: | DIAGNOSTIC CHALLENGE IN DISTINGUISHING BENIGN FROM RARE MALIGNANT UTERINE PATHOLOGY – A CASE REPORT OF A MYXOID LEIOMYOSARCOMA | Authors: | Dimitrov, Goran Tofiloska, Valentina Dzikova, Elena Gjoreski, Josif Biljan, Aleksandra |
Keywords: | leiomyosarcoma sarcoma rare uterus uterine malignancy |
Issue Date: | 2023 | Publisher: | SHMSHM - AAMD | Journal: | Medicus | Abstract: | Leiomyosarcomas are rare aggressive soft tissue tumors, which account for 1 to 2% of all uterine malignancies. Due to their infrequency, as well as the difficulty to distinguish them from leiomyomas, the diagnosis is often made postoperatively. We report a case of a 38-year-old patient who was treated at the University Clinic for Obstetrics and Gynecology – Skopje for an enlarging uterine fibroid, for which she had undergone a myomectomy. The histopathology report showed that it was a case of a myxoid leiomyosarcoma, FIGO Stage IB, involving margins. She was admitted for a reoperation which consisted of a total hysterectomy, bilateral adnexectomy, selective lymphadenectomy and staging. The final postoperative clinical stage was FIGO IB. Leiomyosarcomas are generally less responsive to chemotherapy or radiation, most often have a poor prognosis and a high risk of recurrence. Surgery is the most significant treatment modality. The prognosis primarily depends on the FIGO stage, as the most important independent variable associated with survival. | URI: | http://hdl.handle.net/20.500.12188/30935 |
Appears in Collections: | Faculty of Medicine: Journal Articles |
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File | Description | Size | Format | |
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medicus-gusht-2023.pdf.crdownload | 3.5 MB | Adobe PDF | View/Open |
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