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http://hdl.handle.net/20.500.12188/30585| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Samardjiski, Igor | en_US |
| dc.contributor.author | Simeonova Krstevska, Slagjana | en_US |
| dc.contributor.author | Livrinova, Vesna | en_US |
| dc.contributor.author | Todorovska, Irena | en_US |
| dc.contributor.author | Paneva, I. | en_US |
| dc.contributor.author | Joksimovich, Marija | en_US |
| dc.contributor.author | Atanasova Boshku, Aleksandra | en_US |
| dc.date.accessioned | 2024-06-14T08:16:17Z | - |
| dc.date.available | 2024-06-14T08:16:17Z | - |
| dc.date.issued | 2024-02 | - |
| dc.identifier.uri | http://hdl.handle.net/20.500.12188/30585 | - |
| dc.description.abstract | Preeclampsia (PE) is a multisystem disorder in pregnancy with a specific collection of signs and symptoms as a result of serious dysfunction of multiple organs. Abnormal placentation in the first trimester, most likely triggers the disbalance of the placental anti-angiogenic factor soluble fms-like tyrosine kinase-1(sFlt-1) and pro-angiogenic placental growth factor (PlGF), which result in systemic endothelial dysfunction (injury) to progressive end-organ damage. According the PROGNOSIS study, the cut-off value of the sFlt-1/PlGF ratio over 85 confirms the suspected PE and proved to be useful in preeclampsia diagnosis. A severely elevated sFlt-1/PlGF ratio is associated closely with the need to deliver within 48hours. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Elsevier BV | en_US |
| dc.relation.ispartof | European Journal of Obstetrics & Gynecology and Reproductive Biology | en_US |
| dc.title | Postpartum decline in sflt-1/plgf ratio confirms placental source of angiogenic imbalance and endothelial dysfunction in preeclampsia | en_US |
| dc.type | Article | en_US |
| dc.identifier.doi | 10.1016/j.ejogrb.2023.08.029 | - |
| dc.identifier.url | https://api.elsevier.com/content/article/PII:S0301211523003354?httpAccept=text/xml | - |
| dc.identifier.url | https://api.elsevier.com/content/article/PII:S0301211523003354?httpAccept=text/plain | - |
| dc.identifier.volume | 293 | - |
| dc.identifier.fpage | 5 | - |
| item.grantfulltext | none | - |
| item.fulltext | No Fulltext | - |
| crisitem.author.dept | Faculty of Medicine | - |
| crisitem.author.dept | Faculty of Medicine | - |
| crisitem.author.dept | Faculty of Medicine | - |
| Appears in Collections: | Faculty of Medicine: Journal Articles | |
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