Dilated cardiomyopathy in acromegaly - Case report

Abstract

Introduction: Patients diagnosed with acromegaly develop many cardiovascular complications such as hypertension, arrhythmia, systolic and diastolic dysfunction, valvular dysfunction and heart failure. Dilated cardiomyopathy (DCM) with systolic and diastolic dysfunction is relatively rare but is associated with high mortality to 60%. In MCC the heart muscle gradually dilate and the dysfunction that develops is irreversible. It is therefore necessary early diagnosis and treatment of acromegaly by removal of the tumor and drug treatment with drugs that prevent the heart failure. Material and methods: We present a case of acromegaly diagnosed at the patient at the age of 27 with pituitary macroadenom, hipopituitarizam, diabetes,insipiden diabetes and atrophy of the optic nerve. The patient was subjected to endoscopic surgery but the disease remained active and she was treated with radiotherapy. Our patient has ignored the underlying disease and didn’t call in to the review and controls. The patient was hospitalized with difficult situation of heart failure with anasarca, hypertension, fatigue and severe left ventricular dysfunction with global hypocinesia in the Clinic for Cardiology. She was treated with diuretics, cardiotonics, vasodilators and hormone replacement therapy. Conclusion: Early diagnosis and prompt treatment of acromegaly can prevent irreversible cardiomyopathy. The problem is greater, if it is associated with other morbidities such as hypertension and diabetes.