Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12188/29277
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bitoljanu, Natasha | en_US |
dc.contributor.author | Ivcheva, Ana | en_US |
dc.contributor.author | Belakaposka Srpanova, Viktorija | en_US |
dc.contributor.author | CHakar, LJupcho | en_US |
dc.contributor.author | Siamkouri, Rosica | en_US |
dc.contributor.author | Stankov, Aleksandar | en_US |
dc.contributor.author | Pavlovski, Goran | en_US |
dc.contributor.author | Risteski, Sasho | en_US |
dc.contributor.author | Jakjovski, Zlatko | en_US |
dc.date.accessioned | 2024-02-12T12:47:56Z | - |
dc.date.available | 2024-02-12T12:47:56Z | - |
dc.date.issued | 2023 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12188/29277 | - |
dc.description.abstract | Accurate estimation of wound age is a very important task in forensic medicine field, because it can helps in reconstruction of crime scene. IL-1β is proinflamatory cytokine and plays a major role in wound healing process. The aim of the study is to develop a method for the reliable estimation of dermal injury age. In this study the expression of IL-1β mRNA was evaluated by real-time PCR at skin human wounds with different post-injuried period. We collected 27 human skin wound samples from forensic autopsy cases at our Institute. In our study were include samples from lacerations, incised wounds and stab wounds, with a known time of injury and death. Wound samples were divided into five groups: control group (n=5); first group consisted of cases with immediate death (n=7); second group consisted of cases with survival from 1 hour to 6 hours (n=5); the third group comprised cases with survival from 6 hours to 72 hours (n=3); the fourth group comprised cases with survival from 72 hours to 168 hours (n=7). In this study we detected increased expression levels of IL-1 β mRNA in the second group with survival time from 1 to 6 hours. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Macedonian Association of Anatomists and Morphologists | en_US |
dc.relation.ispartof | JMS - Journal of Morphological Sciences | en_US |
dc.subject | IL-1β | en_US |
dc.subject | wound age | en_US |
dc.subject | real-time PCR | en_US |
dc.subject | autopsy cases | en_US |
dc.subject | human dermal injuries | en_US |
dc.title | TIME-DEPENDENT EXPRESSION OF IL-1β mRNA - A PRELIMINARY STUDY FOR POSSIBLE WOUND AGE MARKER | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.55302/jms2361121b | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
Appears in Collections: | Faculty of Medicine: Journal Articles |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.