Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12188/28815
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dc.contributor.authorArnaudova Danevska, Ivanaen_US
dc.contributor.authorJakjovska, Tatjanaen_US
dc.contributor.authorZendelovska, Dragicaen_US
dc.contributor.authorAtanasovska, Emilijaen_US
dc.contributor.authorDzekova Vidimliski, Pavlinaen_US
dc.contributor.authorPetrushevska, Marijaen_US
dc.contributor.authorBoshkovska, Katerinaen_US
dc.contributor.authorPopova, Goricaen_US
dc.contributor.authorTasevska, Elena Gjinovskaen_US
dc.contributor.authorBalkanov, Trajanen_US
dc.date.accessioned2023-12-12T12:05:41Z-
dc.date.available2023-12-12T12:05:41Z-
dc.date.issued2023-03-01-
dc.identifier.urihttp://hdl.handle.net/20.500.12188/28815-
dc.description.abstractBackground/aim: Allergic rhinitis (AR) is characterized by chronic inflammation of the nasal mucosa. Under the influence of exogenous factors - allergens, reactive oxygen species (ROS) are released during cellular metabolism. They induce a series of pathological changes in the mucosa. Oxidative stress is а result of an imbalance between the production of ROS and the ability to neutralize them. The aim of this study is to compare the levels of oxidative stress between healthy children and children with allergic rhinitis. Material and methods: A total number of 60 children were included (30 healthy children and 30 children with AR). The oxidative stress index was determined by using the FRAS 5 (Free Radical Analytical System) Bravo system. Demographic characteristics, medical history, children's living conditions and eating habits were obtained from the questionnaire. Anthropometric measurements and the absolute number of eosinophils in the peripheral smear were performed on each child. Results: This study showed high oxidative stress index and a significantly higher value of the absolute number of eosinophils in the peripheral smear in children with AR in comparison to healthy children (p<0.05). The group of children with AR had more atopic characteristics and was more exposed to passive smoking than healthy children. Conclusion: Compared to healthy children, children with AR have a high index of oxidative stress, despite of the very high mean value of the concentration of water-soluble antioxidants in serum (PAT test) in the group of children with AR.en_US
dc.language.isoenen_US
dc.publisherWalter de Gruyter GmbHen_US
dc.relation.ispartofPrilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)en_US
dc.titleComparison of Oxidative Stress Levels in Healthy Children and Children with Allergic Rhinitisen_US
dc.typeArticleen_US
dc.identifier.doi10.2478/prilozi-2023-0003-
dc.identifier.urlhttps://www.sciendo.com/pdf/10.2478/prilozi-2023-0003-
dc.identifier.volume44-
dc.identifier.issue1-
dc.identifier.fpage17-
dc.identifier.lpage26-
item.fulltextNo Fulltext-
item.grantfulltextnone-
crisitem.author.deptFaculty of Medicine-
crisitem.author.deptFaculty of Medicine-
crisitem.author.deptFaculty of Medicine-
crisitem.author.deptFaculty of Medicine-
crisitem.author.deptFaculty of Medicine-
crisitem.author.deptFaculty of Medicine-
crisitem.author.deptFaculty of Medicine-
crisitem.author.deptFaculty of Medicine-
Appears in Collections:Faculty of Medicine: Journal Articles
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