Diagnostic value of brush border enzymes of the proximal renal tubules in rheumatoid arthritis

Journal
Clinical laboratory
Date Issued
2011
Author(s)
Masin-Spasovska, Jelka
Nada, Marina
Calovski, Jordan
Osmani, Baskim
Sotirova, Tatjana
Dukovski, Dusko
Ljatifi, Arif
Abstract
Proximal tubules of the kidney have a dominant function in the excretion of different enzymes in the urine. These enzymes can be used as markers for secondary renal damage under the action of different diseases, medicines, and toxins. The aim of this study was to evaluate the values of alanine aminopeptidase (AAP), gamma-glutamyl transferase (gamma-GT), and beta2 microglobulin (beta2m) in urine of patients with untreated rheumatoid arthritis (RA) and to define the possible association between untreated rheumatoid arthritis and tubular function at the brush border region.
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