Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12188/25014
DC Field | Value | Language |
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dc.contributor.author | Kubelka, Katerina | en_US |
dc.contributor.author | Basheska, Neli | en_US |
dc.contributor.author | Yashar, Genghis | en_US |
dc.contributor.author | Prodanova, Irina | en_US |
dc.contributor.author | Ivkovski, Ljube | en_US |
dc.contributor.author | Zografski, George | en_US |
dc.date.accessioned | 2022-12-19T13:07:45Z | - |
dc.date.available | 2022-12-19T13:07:45Z | - |
dc.date.issued | 2001-09 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12188/25014 | - |
dc.description.abstract | Introduction: Benign and malignant pigmented lesions (PL) of the FGT are uncommon, predominantly affecting the vulva. Methods: We report the clinical and pathological features of the 15 PL of the FGT retrieved in a 12-year, retrospective analysis at our Department. Patient records and archival pathology specimens of 7 benign and 8 malignant PL of the FGT, were reviewed. Results: The mean age of all patients was 47 (range, 28-67). Three patients had vulvar nevi (2 intradermal and 1 dysplastic), while blue nevi ranging 2-10 mm in diameter were accidentally discovered in the endocervix of the hysterectomy specimens in four other patients. Vulvar primary malignant melanomas (PMMs) were uncommon (4 cases), comprising 2.5% of female PMMs and 4.3% of all vulvar malignancies diagnosed between 1989 and 2000. Contrary to other studies, all vulvar PMM in our series were of nodular type, ranging 3-13 mm in depth according to Breslow and III-IV level according to Clark. Within the same period, two patients with malignant PL of the uterine cervix were detected, accounting for 0.13% of all females with malignant cervical neoplasms. One of them had a PMM diagnosed in advanced clinical stage (FIGO III), and the other patient had an unusual pigmented squamous cell carcinoma in liB postoperative stage. There were also 2 cases of delayed unilateral ovarian metastases of cutaneous PMM. The diagnosis in all cases of non-vulvar pigmented lesions was confirmed by immunohistochemistry. Conclusions: Although uncommon, PL especially those affecting rare localizations must be considered as diagnostic possibility in FGT. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer | en_US |
dc.relation.ispartof | Virchows Archiv | en_US |
dc.subject | female genital tract | en_US |
dc.subject | pigmented lesion | en_US |
dc.subject | nevus | en_US |
dc.subject | blue nevus | en_US |
dc.subject | malignant melanoma | en_US |
dc.subject | histopathology | en_US |
dc.subject | immunohistochemistry | en_US |
dc.title | Benign and malignant pigmented lesions of the female genital tract (FGT). Report of 15 cases. | en_US |
dc.type | Proceeding article | en_US |
dc.relation.conference | 18th European Congress of Pathology, September 8-13, 2001, Berlin, Germany. | en_US |
dc.identifier.doi | 10.1007/BF02698641 | - |
item.grantfulltext | open | - |
item.fulltext | With Fulltext | - |
crisitem.author.dept | Faculty of Medicine | - |
Appears in Collections: | Faculty of Medicine: Conference papers |
Files in This Item:
File | Description | Size | Format | |
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ECP 2001 pp335-6.pdf | 473.7 kB | Adobe PDF | View/Open | |
ECP 2001 cover.pdf | 75.39 kB | Adobe PDF | View/Open |
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