Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12188/24887
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dc.contributor.authorDabeski, Drageen_US
dc.contributor.authorDanilovski, Draganen_US
dc.contributor.authorBasheska, Nelien_US
dc.contributor.authorAntovska, Vesnaen_US
dc.contributor.authorStojovski, Marjanen_US
dc.contributor.authorOgnenoska-Jankovska, Biljanaen_US
dc.contributor.authorSima, Anetaen_US
dc.contributor.authorPopovska, Zoraen_US
dc.date.accessioned2022-12-13T13:50:46Z-
dc.date.available2022-12-13T13:50:46Z-
dc.date.issued2016-09-
dc.identifier.urihttp://hdl.handle.net/20.500.12188/24887-
dc.descriptionProceeding & Abstracts of the 2nd Macedonian Congress of Pathology with International Participation, September 1-4, 2016, Ohrid, Macedonia, 2016:118.en_US
dc.description.abstractObjective: The objective of our study was to investigate the correlation between cytology and cervical biopsy findings in women with squamous cell abnormalities on cervical cytology. Material and Methods: A comparative retrospective study was conducted in the period from September 2015 to March 2016 in a series of 184 sexually active women, aged from 20 to 60 years, with squamous cell abnormalities in the liquid-based cytology test. In all women, cervical biopsy with endocervical curettage was performed colposcopically for histopathological analysis. Results: Cytologically, there were 118 (64.13%) atypical squamous cells of undetermined significance (ASC-US), 22 (11.96%) low-grade squamous intraepithelial lesions (LSIL), 38 (20.65%) high-grade squamous intraepithelial lesions (HSIL) and 6 (3.26%) invasive squamous cell carcinoma cases. According to the histopathological findings in the cervical biopsy and/or endocervical curettage material in 108 (58.70%) women only nonneoplastic lesions were diagnosed. Twenty-four (13.04%) women had histologically confirmed LSIL, 42 (22.83%) had HSIL and in 10 (5.43%) cases invasive SCC was confirmed. For all squamous cell abnormalities, the sensitivity of the liquid-based cytology test in LSIL and higher grade lesions was 58.70% (108/184) and false positivity was 41.30% (76/184). Excluding ASC-US lesions, the sensitivity of the liquid-based cytology test was 78.80% (52/66) and the false positivity was 21.21% (14/66). The positive predictive value was 100% (6/6) for invasive SCC, 68.42% (26/38) for HSIL and 31.82% (7/22) for LSIL. Conclusions: The high sensitivity of the liquid-based cytology test for HSILs shows that it is an effective screening test for cervical cancer and its precursor lesions.en_US
dc.language.isoenen_US
dc.publisherMacedonian Association of Pathologyen_US
dc.subjectuterine cervixen_US
dc.subjectsquamous intraepithelial lesions (SIL)en_US
dc.subjectsquamous cell carcinomaen_US
dc.subjectcytologyen_US
dc.subjecthistologyen_US
dc.titleCorrelation between cytopathology and histopathology in women with squamous cell abnormalities of the uterine cervixen_US
dc.typeProceeding articleen_US
dc.relation.conference2nd Macedonian Congress of Pathology with International Participation, September 1-4, 2016, Ohrid, Macedoniaen_US
item.fulltextWith Fulltext-
item.grantfulltextopen-
crisitem.author.deptFaculty of Medicine-
crisitem.author.deptFaculty of Medicine-
crisitem.author.deptFaculty of Medicine-
crisitem.author.deptFaculty of Dentistry-
crisitem.author.deptFaculty of Medicine-
Appears in Collections:Faculty of Medicine: Conference papers
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