Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12188/16821
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bosilkovski, Mile | en_US |
dc.contributor.author | Kirovska, Valerija | en_US |
dc.contributor.author | Grozdanovski, Krsto | en_US |
dc.contributor.author | Vidinic, Ivan | en_US |
dc.contributor.author | Demiri, Ilir | en_US |
dc.contributor.author | Labachevski, Nikola | en_US |
dc.date.accessioned | 2022-03-03T09:52:20Z | - |
dc.date.available | 2022-03-03T09:52:20Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Mile B, Valerija K, Krsto G, Ivan V, Ilir D, Nikola L. Doxycycline-rifampin versus doxycycline-rifampingentamicin in treatment of human brucellosis. Trop Doct. 2012;42(1):13-7. | en_US |
dc.identifier.uri | http://hdl.handle.net/20.500.12188/16821 | - |
dc.description.abstract | This prospective, non-randomized trial, compared the efficacy and tolerance of a doxycycline-rifampin regimen, administered for 45 days, versus doxycycline-rifampin given for 45 days plus gentamicin for the first 7-10 days, in the treatment of human brucellosis. Of 238 patients that were initially included in the study, 181 were finally evaluated. Ninety-four were treated with the doxycycline-rifampin and 87 with the doxycycline-rifampin-gentamicin regimens. In the doxycycline-rifampin group: relapses were noted in 13 (13.8%) patients; therapeutic failures in five (5.3%); and mild adverse effects in 28 (29.8%). In the doxycycline-rifampin-gentamicin group: four (4.6%) relapsed; and five (5.7%) therapeutic failures were registered. Mild adverse effects were registered in 29 (33.3%) patients. The doxycycline-rifampin-gentamicin regimen demonstrated a significantly lower relapse rate compared to the doxycycline-rifampin combination (P = 0.034). We conclude that adding gentamicin for the first 7-10 days to the standard oral doxycycline-rifampin regimen can decrease the rate of relapses. | en_US |
dc.publisher | SAGE Publications | en_US |
dc.relation.ispartof | Tropical Doctor | en_US |
dc.title | Doxycycline-rifampin versus doxycycline-rifampingentamicin in treatment of human brucellosis. | en_US |
dc.type | Article | en_US |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
Appears in Collections: | Faculty of Medicine: Journal Articles |
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