Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12188/15283
DC Field | Value | Language |
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dc.contributor.author | Trajkova, Sanja | en_US |
dc.contributor.author | Stojanovska, Simona | en_US |
dc.contributor.author | Ridova, Nevenka | en_US |
dc.contributor.author | Krstevska balkanov, Svetlana | en_US |
dc.contributor.author | Pivkova Veljanovska, Aleksandra | en_US |
dc.contributor.author | Cevreska, Lidija | en_US |
dc.contributor.author | Popova-Labacevska, Marija | en_US |
dc.contributor.author | Panovska Stavridis, Irina | en_US |
dc.date.accessioned | 2021-10-19T11:47:43Z | - |
dc.date.available | 2021-10-19T11:47:43Z | - |
dc.date.issued | 2021-09-11 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12188/15283 | - |
dc.description.abstract | <jats:p>Introduction: Since December 2019, multiple human cases of novel coronavirus infection were reported, representing with upper respiratory symptoms (influenza-like presentation). The virus was named the Severe acute respiratory system coronavirus 2 (SARS-COV-2). Studies have reported cases of patients with COVID-19 infection, including development of several autoimmune events that suggests that infection with SARS CoV-2 may be associated with initiation of autoimmune hematological autoimmune disorders. Aim: Review the hematological autoimmune phenomenon after infection with SARS-COV-2 in order to assist into the pathogenic mechanisms, clinical manifestations and treatment of this group of patients. Materials and methods: This is a retrospective study that includes 21 patients with autoimmune diseases like secondary immune thrombocytopenia (ITP), autoimmune hemolytic anemia( AIHA) and thrombotic thrombocytopenic purpura (TTP) that have emerged after COVID-19 infection. The patients were diagnosed and treated at the University Clinic of Hematology for a period of time from January 2020 to April 2021. Results: The most common hematologic autoimmune disorder was ITP in 13 cases (62%) followed by AIHA in 5 cases (24%) and TTP in 3 individuals (14%). The mean time of onset of the hematologic auto-immune presentations was 18,4 ± 10,3 days. The therapy of this conditions in patients with COVID-19 infection requires an individualized approach to achieve a precise balance between the risk of severe bleeding and of thromboembolic events. Conclusion: Causal relationship between COVID-19 infection and these autoimmune events still requires further studies. We should all have in mind the risk of development of hematologic autoimmune disorders in infected patients. </jats:p> | en_US |
dc.language.iso | en | en_US |
dc.publisher | Scientific Foundation SPIROSKI | en_US |
dc.relation.ispartof | Open Access Macedonian Journal of Medical Sciences | en_US |
dc.title | Hematologic Autoimmune Manifestation Secondary to Coronavirus Disease 19 Infection – A Single-Center Experience | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.3889/oamjms.2021.6766 | - |
dc.identifier.url | https://oamjms.eu/index.php/mjms/article/download/6766/6047 | - |
dc.identifier.url | https://oamjms.eu/index.php/mjms/article/download/6766/6047 | - |
dc.identifier.volume | 9 | - |
dc.identifier.issue | B | - |
dc.identifier.fpage | 940 | - |
dc.identifier.lpage | 944 | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
crisitem.author.dept | Faculty of Medicine | - |
Appears in Collections: | Faculty of Medicine: Journal Articles |
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